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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2052 [new locus tag: SACOL_RS10740 ]
  • pan locus tag?: SAUPAN005330000
  • symbol: SACOL2052
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2052 [new locus tag: SACOL_RS10740 ]
  • symbol: SACOL2052
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2118160..2118615
  • length: 456
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAATAATGACAAACTTCAGCGAATGGTTGAGAATCTTTCGGAAGAAAAATTTGGACGT
    ACGTTTCGACATTGTGCATATTTTAATAAAAGGTTACGTACAACAGGCGGACGTTATCTT
    TTAAAGTCCCATGATATTGAAATTAATCCAAAACAATATGAGCATTATGGAGAAGATGCT
    GTTGTAAAAATTATACTGCACGAATTGTGTCATTATCACTTGCATATTGCTGGTAAAGGT
    TATCAACATAAAGATCAAGATTTTAAACGATTGAGCCAACAGGTTGGAGCGCCTAGATTT
    TGTAACAGCATTGAAAGCTATCAACAACGGGCAAATTATGAATATTATTGCACTAAATGT
    CATGCAAAATATATACGTATCCGTAAAGTTGATACGAATCGTATGCGTTGCGGACATTGC
    AATGGAAAATTAAGAATGAAAAGACAATTGAAATAA
    60
    120
    180
    240
    300
    360
    420
    456

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2052 [new locus tag: SACOL_RS10740 ]
  • symbol: SACOL2052
  • description: hypothetical protein
  • length: 151
  • theoretical pI: 10.0258
  • theoretical MW: 18185.8
  • GRAVY: -1.01589

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 21.5)
  • TheSEED  :
    • Putative metallopeptidase (Zinc) SprT family
    CBSS-393131.3.peg.612  Putative metallopeptidase (Zinc) SprT family
  • PFAM:
    Peptidase_MA (CL0126) SprT-like; SprT-like family (PF10263; HMM-score: 57)
    and 5 more
    Zn_Beta_Ribbon (CL0167) Zn_ribbon_SprT; SprT-like zinc ribbon domain (PF17283; HMM-score: 41.6)
    Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 21.2)
    no clan defined FlhC; Flagellar transcriptional activator (FlhC) (PF05280; HMM-score: 13.7)
    Zn_Beta_Ribbon (CL0167) zinc_ribbon_12; Probable zinc-ribbon domain (PF11331; HMM-score: 10.6)
    zf-RRN7; Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 (PF11781; HMM-score: 10.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Zn2+
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00798
    • TAT(Tat/SPI): 0.000876
    • LIPO(Sec/SPII): 0.001434
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNNDKLQRMVENLSEEKFGRTFRHCAYFNKRLRTTGGRYLLKSHDIEINPKQYEHYGEDAVVKIILHELCHYHLHIAGKGYQHKDQDFKRLSQQVGAPRFCNSIESYQQRANYEYYCTKCHAKYIRIRKVDTNRMRCGHCNGKLRMKRQLK

⊟Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
  • protein localization: Cytoplasmic [1] [2]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)
  2. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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