Jump to navigation
Jump to search
NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL0566 [new locus tag: SACOL_RS02940 ]
- pan locus tag?: SAUPAN002286000
- symbol: nupC
- pan gene symbol?: nupC
- synonym:
- product: nucleoside permease NupC
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL0566 [new locus tag: SACOL_RS02940 ]
- symbol: nupC
- product: nucleoside permease NupC
- replicon: chromosome
- strand: -
- coordinates: 586624..587838
- length: 1215
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3237616 NCBI
- RefSeq: YP_185454 NCBI
- BioCyc: see SACOL_RS02940
- MicrobesOnline: 912047 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201ATGCATATTCTAATTGGGATTATCGGAATTATCTTCTTTTTAGCACTTGCGTTTCTATTT
AGCTCAGACAGGAAAAATATTCGCTGGAAATATGTAGGAATTTTACTTGCAATTCAGCTT
ATCTTTGCATTTATCTTGCTTAAAACTACAATGGGAATCAAGGTTATTGGTGGTATTTCA
AACGGTTTTAACTACTTATTATTAAAAGCAGCAGATGGTGTTAACTTTGTATTCGGTGGT
ATTCAATATATCGATCCTAAGCAACCACCATTCTTCTTCAGTGTATTATTACCTATCGTA
TTTATTTCAGCGATTATCGGTATCCTTCAATACACAAAGATTTTACCTTTAATCATTAAT
GTTTTAGGATTCTTAATTTCTAAAATTAATGGTATGGGACGTTTAGAATCATACAATGCA
GTTGCTGCAGCAATTTTGGGACAATCTGAAGTATTTATTTCAATTAAAAAACAATTACCA
TACATACCTAAGCAACGTTTATACACATTAACAGCTTCAGCAATGTCGACTGTTTCTGCT
TCAATTATCGGTGCATACTTTACCTTAATTGAACCTAAATATGTTGTAACGGCTGTTGTC
TTAAACTTATTTGGTGGTTTCATCATCGCTTCAATTATTAACCCTTATAAAGTTAATGAA
GAAGATGACAAATTATTAGTTGAAGAAACTGAAGAAAGACAACAATCATTCTTCGAAATG
CTAGGAGAATATATTTTAGATGGATTTAAAGTAGCTGTCATTGTAGGCGCAATGTTAATC
GGATACATTGCCATTATCGCTCTATTAAATGGAATTGTAAGCAATATCTTTAGTACAGTT
TCAGGTGGCGCTATTTCTTGGGATTTCCAAACATTAATTGGTTTTGTCTTTGCACCATTT
GCATTCTTAGTCGGTGTGCCATGGCAAGATGCAGTTCAAGCCGGTTCAGTTATGGCGACA
AAACTATTATCTAACGAATTTGTAGCAATGCAAGCACTTGGTAAACTTAGTGATTTATCT
GAACACGCAAAAGGTGTTACATCTGTATTCTTAGTATCATTTGCTAACTTTAGCTCTATC
GGTATTATTTCAGGTGCGATTAAATCACTTAATGACAAAAAAGGAGATACAGTTGCCCGC
TTTGGTTTGAAATTATTATTCGGTGCAACACTAGTATCTTTCATTTCAGCTGCAATCGCT
GGATTCTTTATTTAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
960
1020
1080
1140
1200
1215
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL0566 [new locus tag: SACOL_RS02940 ]
- symbol: NupC
- description: nucleoside permease NupC
- length: 404
- theoretical pI: 9.44764
- theoretical MW: 43804.7
- GRAVY: 0.870792
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Nucleosides, purines and pyrimidines nucleoside transporter, NupC family (TIGR00804; HMM-score: 433.4)
- TheSEED :
- Nucleoside permease NupC
and 1 more - PFAM: no clan defined Nucleos_tra2_C; Na+ dependent nucleoside transporter C-terminus (PF07662; HMM-score: 210.9)and 2 moreNucleos_tra2_N; Na+ dependent nucleoside transporter N-terminus (PF01773; HMM-score: 75.6)Gate; Nucleoside recognition (PF07670; HMM-score: 25)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 10
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0
- Signal peptide possibility: -0.5
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.011503
- TAT(Tat/SPI): 0.000267
- LIPO(Sec/SPII): 0.060914
- predicted transmembrane helices (TMHMM): 10
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MHILIGIIGIIFFLALAFLFSSDRKNIRWKYVGILLAIQLIFAFILLKTTMGIKVIGGISNGFNYLLLKAADGVNFVFGGIQYIDPKQPPFFFSVLLPIVFISAIIGILQYTKILPLIINVLGFLISKINGMGRLESYNAVAAAILGQSEVFISIKKQLPYIPKQRLYTLTASAMSTVSASIIGAYFTLIEPKYVVTAVVLNLFGGFIIASIINPYKVNEEDDKLLVEETEERQQSFFEMLGEYILDGFKVAVIVGAMLIGYIAIIALLNGIVSNIFSTVSGGAISWDFQTLIGFVFAPFAFLVGVPWQDAVQAGSVMATKLLSNEFVAMQALGKLSDLSEHAKGVTSVFLVSFANFSSIGIISGAIKSLNDKKGDTVARFGLKLLFGATLVSFISAAIAGFFI
⊟Experimental data[edit | edit source]
- experimentally validated: PeptideAtlas
- protein localization: Integral membrane [1] [2]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator: CcpA regulon
CcpA (TF) important in Carbon catabolism; RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e) - ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)