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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1393
  • pan locus tag?: SAUPAN004145000
  • symbol: SA1393
  • pan gene symbol?: ccpN
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1393
  • symbol: SA1393
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1599418..1600041
  • length: 624
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATAGAACTCAGTCAAAGACAAGAACGAATCATCGAAATTGTTAAAACTAAAGGACCCATT
    ACTGGTGAACAAATAGCAGATAAGTTGAATTTAACAAGAGCAACGCTTAGACCAGATTTA
    GCGATATTAACAATGTCAGGTTTTTTAGAAGCGCGTCCCCGAGTTGGATATTATTATTCA
    GGTAAATCAAAAGGCAAATTTTTTAATGAAAAACTTCGACAATTTGAGGTTAAGGACTAT
    ATGTCTCAACCTGTTGTGCTAAGAGAGAATACAACAGTTTATGACGCTATTTGTACAATT
    TTTTTAGAAGATGTAAGTACATTATTTATTATTAATGAAGATAACGATTTTGTTGGTGTG
    TGTTCAAGAAAAGATTTATTAAGAGCTTCAATGATTGGAGCAGATATTCATACAGTACCT
    ATCAGTGTAAATATGACACGTATGCCTAATGTCACTTATTTAGAGGAAAGCGAATTAGTC
    ATATACGCAGCAGATAGAATGATTGAAAAAGAAATTGATTCGATTCCAATTGTAAGAAAA
    AAAGATAATCAAAAGTATGAAGTAATTGGAAGAATTTCCAAAACAACAATAGCTAAGTTA
    TTAGTAGCATTATATAAAGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    624

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1393
  • symbol: SA1393
  • description: hypothetical protein
  • length: 207
  • theoretical pI: 8.1547
  • theoretical MW: 23708.4
  • GRAVY: -0.17971

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Sugars sugar isomerase, KpsF/GutQ family (TIGR00393; HMM-score: 27.9)
    and 3 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis inosine-5'-monophosphate dehydrogenase (TIGR01302; EC 1.1.1.205; HMM-score: 18.7)
    Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 17.9)
    Metabolism Amino acid biosynthesis Serine family cystathionine beta-synthase (TIGR01137; EC 4.2.1.22; HMM-score: 14.1)
  • TheSEED  :
    • Transcriptional repressor CcpN, MarR family
  • PFAM:
    no clan defined CBS; CBS domain (PF00571; HMM-score: 54.4)
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 49.5)
    and 11 more
    HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 25.6)
    MarR; MarR family (PF01047; HMM-score: 20.4)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 16.5)
    HTH_Mga; M protein trans-acting positive regulator (MGA) HTH domain (PF08280; HMM-score: 15.4)
    GntR; Bacterial regulatory proteins, gntR family (PF00392; HMM-score: 14.2)
    TFIIE_alpha; TFIIE alpha subunit (PF02002; HMM-score: 13.6)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 13.6)
    HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 13.1)
    DUF977; Bacterial protein of unknown function (DUF977) (PF06163; HMM-score: 12.8)
    HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 12.6)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006653
    • TAT(Tat/SPI): 0.00173
    • LIPO(Sec/SPII): 0.001151
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MELSQRQERIIEIVKTKGPITGEQIADKLNLTRATLRPDLAILTMSGFLEARPRVGYYYSGKSKGKFFNEKLRQFEVKDYMSQPVVLRENTTVYDAICTIFLEDVSTLFIINEDNDFVGVCSRKDLLRASMIGADIHTVPISVNMTRMPNVTYLEESELVIYAADRMIEKEIDSIPIVRKKDNQKYEVIGRISKTTIAKLLVALYKE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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