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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS11740 [old locus tag: NWMN_2033 ]
  • pan locus tag?: SAUPAN005424000
  • symbol: NWMN_RS11740
  • pan gene symbol?: —
  • synonym:
  • product: N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS11740 [old locus tag: NWMN_2033 ]
  • symbol: NWMN_RS11740
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 2250306..2251166
  • length: 861
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (2250306..2251166) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_2033

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGGCTAAAGAACTTTGTTTTGAAGGTATCACTTTAAAAGCATTTGATGAACAATATCGT
    TCAGCAATTAATGATTTTGACTTGAATGAAAGACAACAAATATATTCATCTTTACCTAAA
    GAAGTTATTGATGATGCAATTAATGATGCTGATAGGATTGCTAACGTAGCAATAAACGAT
    AAAAATGAAGTGGTGGGCTTTTTTGTATTACATCGTTACTATCAGCATGAAGGTTATGAT
    ACACCTGAAAATGTCGTTTATATTCGTTCATTATCGATTAATGAAAAATATCAAGGTTTT
    GGATATGGCACGAAAATAATGATGTCATTGCCGCAATATGTTCAAGGTGTATTTCCTGAT
    TTTAATCATCTATATCTAGTAGTAGATGCGGAAAATGACAATGCTTGGAACCTATACGAA
    CGTGCTGGATTCATGCATACAGCGACTAAAGAAGAAGGACCAATTGGCAAAGAACGACTA
    TATTACTTGGACTTAGATTCAAAACATGTTTCATCATTAAAGCTTGAAGAAGAAAGTCGT
    TCAGAAGTGACCAATGTACATATCATTAATTTAATGATTGATGGCCAAAAGGTTGGCTTT
    ATCGCATTGGAGCAGATTGGTGAACGCATGAACATTGCTGCTATTGAAGTGGATAAATCA
    TATCGCTTTAATGGTATTGGTTCAAGTGCTCTGCGACAATTGCCAACTTACTTAAGAAAA
    AACTATGACAACCTTAATGTGATTACGATGATTCTGTTTGGAGAGAATAATGATTTTAAA
    CCATTATGTTTAAATAGTAATTTCGTTGAAATCGAACAAACTGATGATTATGTCGTTTTC
    GAAAAATATTTAAATTACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    861

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS11740 [old locus tag: NWMN_2033 ]
  • symbol: NWMN_RS11740
  • description: N-acetyltransferase
  • length: 286
  • theoretical pI: 4.45913
  • theoretical MW: 33110
  • GRAVY: -0.377273

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 58.5)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 26.4)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 18.8)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 72.9)
    and 10 more
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 46.5)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 46.1)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 29.5)
    Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 25.1)
    FR47; FR47-like protein (PF08445; HMM-score: 24.5)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 22)
    GNAT_acetyltr_2; GNAT acetyltransferase 2 (PF13718; HMM-score: 18)
    GAF (CL0161) GAF_3; GAF domain (PF13492; HMM-score: 15.4)
    no clan defined Phage_RpbA; Phage RNA polymerase binding, RpbA (PF10789; HMM-score: 13.6)
    Acetyltrans (CL0257) Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 12.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002243
    • TAT(Tat/SPI): 0.000179
    • LIPO(Sec/SPII): 0.000367
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAKELCFEGITLKAFDEQYRSAINDFDLNERQQIYSSLPKEVIDDAINDADRIANVAINDKNEVVGFFVLHRYYQHEGYDTPENVVYIRSLSINEKYQGFGYGTKIMMSLPQYVQGVFPDFNHLYLVVDAENDNAWNLYERAGFMHTATKEEGPIGKERLYYLDLDSKHVSSLKLEEESRSEVTNVHIINLMIDGQKVGFIALEQIGERMNIAAIEVDKSYRFNGIGSSALRQLPTYLRKNYDNLNVITMILFGENNDFKPLCLNSNFVEIEQTDDYVVFEKYLNY

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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