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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS11130 [old locus tag: NWMN_1929 ]
  • pan locus tag?: SAUPAN005193000
  • symbol: NWMN_RS11130
  • pan gene symbol?: —
  • synonym:
  • product: succinyl-diaminopimelate desuccinylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS11130 [old locus tag: NWMN_1929 ]
  • symbol: NWMN_RS11130
  • product: succinyl-diaminopimelate desuccinylase
  • replicon: chromosome
  • strand: +
  • coordinates: 2135868..2137091
  • length: 1224
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (2135868..2137091) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1929

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGACAACTTTTAGTGAAAAAGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAA
    ACTGAAAATAATAATGAAATAGACGTTTGTAATTATTTAACAGATTTATTCGACAAGTAC
    GATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCGCCAATATCGTTGCAGAAATC
    GGTAACGGCTCACCTATACTCGCATTGAGTGGTCATATGGATGTTGTTGATGCAGGAAAT
    CAAGATAATTGGTCATATCCCCCTTTTCAACTGACAGAAAAAGATGGCAAATTATATGGC
    CGAGGCACTACAGATATGAAAGGCGGTTTAATGGCTTTGGTCGTATCTCTAATCGAATTA
    AAAGAACAAAATGAATTGCCTCATGGAACGATTAGATTACTGGCTACTGCTGGCGAAGAG
    AAAGAACAAGAAGGTGCCAAATTATTAGCTGATAAAGGCTATTTAGACGATGTCGATGGC
    TTAATTATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAGGGGTCTATGTCA
    TGTAAAGTAACTGCAACTGGTAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAAT
    GCAATTGATACACTGCTTGAATTTTATAATCTATTTAAAGAAAAATATTCAGAGCTTAAA
    CAACAAGATACTAAACATGAATTAGATGTTGCGCCTATGTTCAAATCATTGATTGGAAAA
    GAAATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATA
    AATGGCGGCAAACAATTTAACTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGA
    CCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTTTCCAAAATATCATTAATGAT
    GTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAATCACCGACCTGTAACAAGCGAT
    AAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAGAACAAGAC
    GAAATATTTGTTTCAGCGCTTGTAGGTGCAACAGATGCCTCTAGTTTCTTAGGAGATAAT
    AAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATCCATTAATGGCACATCAAATC
    GATGAATATATTGAAAAAGATATGTATCTGAAATATATTGATATTTTTAAAGAGGCTTCC
    ATTCAATATTTAAAAGAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1224

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS11130 [old locus tag: NWMN_1929 ]
  • symbol: NWMN_RS11130
  • description: succinyl-diaminopimelate desuccinylase
  • length: 407
  • theoretical pI: 4.27856
  • theoretical MW: 45097.3
  • GRAVY: -0.329975

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase, ArgE/DapE family (TIGR01910; EC 3.4.-.-; HMM-score: 300.7)
    and 11 more
    Metabolism Amino acid biosynthesis Glutamate family acetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 167.9)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01246; EC 3.5.1.18; HMM-score: 134.5)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 122)
    putative selenium metabolism hydrolase (TIGR03526; HMM-score: 114.6)
    N-acetyl-ornithine/N-acetyl-lysine deacetylase (TIGR01902; HMM-score: 100.7)
    putative dipeptidase (TIGR01887; EC 3.4.13.-; HMM-score: 95.3)
    N-acyl-L-amino-acid amidohydrolase (TIGR01880; EC 3.5.1.14; HMM-score: 78.3)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides amidohydrolase (TIGR01891; HMM-score: 75.6)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides dipeptidase PepV (TIGR01886; EC 3.4.13.-; HMM-score: 51.8)
    peptidase T-like protein (TIGR01883; HMM-score: 31.3)
    Xaa-His dipeptidase (TIGR01893; EC 3.4.13.20; HMM-score: 29.2)
  • TheSEED: see NWMN_1929
  • PFAM:
    ZnExoPePases (CL0865) Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 133.6)
    and 2 more
    no clan defined M20_dimer; Peptidase dimerisation domain (PF07687; HMM-score: 78.6)
    ZnExoPePases (CL0865) Peptidase_M28; Peptidase family M28 (PF04389; HMM-score: 27.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9635
    • Cytoplasmic Membrane Score: 0.0242
    • Cell wall & surface Score: 0.0025
    • Extracellular Score: 0.0097
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003302
    • TAT(Tat/SPI): 0.000133
    • LIPO(Sec/SPII): 0.000511
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLTDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWSYPPFQLTEKDGKLYGRGTTDMKGGLMALVVSLIELKEQNELPHGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNLFKEKYSELKQQDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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