PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_RS10255 [old locus tag: NWMN_1795 ]
• pan locus tag^?: SAUPAN001719000
• symbol: NWMN_RS10255
• pan gene symbol^?: rinA
• synonym:
• product: transcriptional regulator

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_RS10255 [old locus tag: NWMN_1795 ]
• symbol: NWMN_RS10255
• product: transcriptional regulator
• replicon: chromosome
• strand: -
• coordinates: 2006826..2007248
• length: 423
• essential: unknown other strains

⊟Accession numbers

• Location: NC_009641 (2006826..2007248) NCBI
• BioCyc:
• MicrobesOnline: see NWMN_1795

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  421
  
  ATGACTAAAAAGAAATACGGATTAAAATTATCAACAGTTCGAAAGTTAGAAGATGAGTTG
  TGTGATTATCCTAATTATCATAAACAACTTGAAGATTTAAGAAGTGAAATAATGACACCG
  TGGATTCCAACAGATACAAATATAGGCGGGGAGTTTGTACCGTCTAATACATCAAAAACA
  GAAATGGCAGTAACTAATTATCTTTGTAGTATACGAAGAGGTAAAATTCTTGAGTTTAAG
  AGTGCGATTGAACGTATAATCAACACATCAAGTAGGAAAGAACGCGAATTCATTCAAGAG
  TATTATTTTAATAAAAAGACTTTGATTGCGGTTTGTTATGACATACACATCTCTGAAAGT
  ACAGCGCATAGAATCAAGAAGAAAATAGTGTCTAAACTAGCCGAAGAATTAGGAGAATGC
  TAA
  60
  120
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  240
  300
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  420
  423
  

⊟Protein

⊟General

• locus tag: NWMN_RS10255 [old locus tag: NWMN_1795 ]
• symbol: NWMN_RS10255
• description: transcriptional regulator
• length: 140
• theoretical pI: 8.86509
• theoretical MW: 16329.8
• GRAVY: -0.565714

⊟Function

• TIGRFAM:
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage transcriptional regulator, RinA family (TIGR01636; HMM-score: 201.3)
  Signal transduction Regulatory functions DNA interactions phage transcriptional regulator, RinA family (TIGR01636; HMM-score: 201.3)
  and 9 more
  RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 29.3)
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage transcriptional regulator, ArpU family (TIGR01637; HMM-score: 27.3)
  Signal transduction Regulatory functions DNA interactions phage transcriptional regulator, ArpU family (TIGR01637; HMM-score: 27.3)
  Cellular processes Cellular processes Sporulation and germination RNA polymerase sigma-F factor (TIGR02885; HMM-score: 21.4)
  Genetic information processing Transcription Transcription factors RNA polymerase sigma-F factor (TIGR02885; HMM-score: 21.4)
  RNA polymerase sigma-70 factor, sigma-B/F/G subfamily (TIGR02980; HMM-score: 20.5)
  RNA polymerase sigma factor, FliA/WhiG family (TIGR02479; HMM-score: 16)
  Cellular processes Cellular processes Sporulation and germination RNA polymerase sigma-G factor (TIGR02850; HMM-score: 12.3)
  Genetic information processing Transcription Transcription factors RNA polymerase sigma-G factor (TIGR02850; HMM-score: 12.3)
• TheSEED: data available for NCTC8325
• PFAM:
  HTH (CL0123) DUF1492; Protein of unknown function (DUF1492) (PF07374; HMM-score: 24.6)
  Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 21.8)
  and 3 more
  HTH_Tnp_4; Helix-turn-helix of DDE superfamily endonuclease (PF13613; HMM-score: 15.3)
  EF_hand (CL0220) Ca_chan_IQ; Voltage gated calcium channel IQ domain (PF08763; HMM-score: 13.5)
  SOCS_box (CL0642) VHL_C; VHL box domain (PF17211; HMM-score: 12.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.024404
  • TAT(Tat/SPI): 0.00058
  • LIPO(Sec/SPII): 0.002147
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446084845 NCBI
• RefSeq: WP_000162700 NCBI
• UniProt: see NWMN_1795

⊟Protein sequence

• MTKKKYGLKLSTVRKLEDELCDYPNYHKQLEDLRSEIMTPWIPTDTNIGGEFVPSNTSKTEMAVTNYLCSIRRGKILEFKSAIERIINTSSRKEREFIQEYYFNKKTLIAVCYDIHISESTAHRIKKKIVSKLAEELGEC

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications