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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS08895 [old locus tag: NWMN_1586 ]
- pan locus tag?: SAUPAN004317000
- symbol: NWMN_RS08895
- pan gene symbol?: phoP
- synonym:
- product: DNA-binding response regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS08895 [old locus tag: NWMN_1586 ]
- symbol: NWMN_RS08895
- product: DNA-binding response regulator
- replicon: chromosome
- strand: -
- coordinates: 1757199..1757903
- length: 705
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGTCGCAAAAAGTGTTGGTAGTAGATGACGAACATTCAATCGTAACATTACTTAAATAT
AACTTAGAAACAGCTGGTTATGAAGTTGTTGTCGCATTTGATGGTGATGAGGCTTTAGAA
AAGGTAGAAAGTGAACAGCCAGATTTAATTATTTTAGATGTTATGCTACCTAAAAAAGAT
GGCATTGACGTATGTAAGACTGTAAGAACAAATAAAAATTTAGTCCCTATATTAATGTTA
ACGGCGAAAAATGATGAATTTGATCGGGTATTAGGTTTAGAATTAGGTGCCGATGACTAT
ATGACTAAGCCTTTTTCACCTAGAGAAGTTGTTGCCCGTGTGAAAGCCATTTTAAGACGT
TCTCAATTTGTAAAAGAAGTAGAAGAGATTGACGATGATATTACCATCGGATCGATACGT
ATTAGACCCGATTATTTTGAAGTATATAAGCATAATGAGTTATTGGAGCTAACACCGAAA
GAATTTGAACTCTTGCTTTATTTGATAGAAAGACAAGGCAGAGTCATTACGAGAGAGCAT
ATGTTAAATACGGTATGGAATTATGAATTTGCAGGAGACTCAAGAATTGTTGATGTACAT
ATCAGTCATTTAAGAGATAAATTAGAAGATAATCCTAAGAAGCCACAACTTATTAAAACT
GTGCGTGGCTTAGGCTATAAATTGGAAAGACCTAAAGAACAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS08895 [old locus tag: NWMN_1586 ]
- symbol: NWMN_RS08895
- description: DNA-binding response regulator
- length: 234
- theoretical pI: 4.90242
- theoretical MW: 27122.1
- GRAVY: -0.345299
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions phosphate regulon transcriptional regulatory protein PhoB (TIGR02154; HMM-score: 241.6)Signal transduction Two-component systems phosphate regulon transcriptional regulatory protein PhoB (TIGR02154; HMM-score: 241.6)and 8 moreRegulatory functions DNA interactions heavy metal response regulator (TIGR01387; HMM-score: 191.2)proteobacterial dedicated sortase system response regulator (TIGR03787; HMM-score: 138.6)Central intermediary metabolism Nitrogen metabolism nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 76.9)Regulatory functions DNA interactions nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 76.9)Signal transduction Two-component systems nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 76.9)Cellular processes Sporulation and germination sporulation transcription factor Spo0A (TIGR02875; HMM-score: 64.1)Regulatory functions DNA interactions PEP-CTERM-box response regulator transcription factor (TIGR02915; HMM-score: 44.3)Signal transduction Two-component systems TMAO reductase sytem sensor TorS (TIGR02956; EC 2.7.13.3; HMM-score: 38.6)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: CheY (CL0304) Response_reg; Response regulator receiver domain (PF00072; HMM-score: 106.2)HTH (CL0123) Trans_reg_C; Transcriptional regulatory protein, C terminal (PF00486; HMM-score: 104)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001974
- TAT(Tat/SPI): 0.000101
- LIPO(Sec/SPII): 0.000244
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSQKVLVVDDEHSIVTLLKYNLETAGYEVVVAFDGDEALEKVESEQPDLIILDVMLPKKDGIDVCKTVRTNKNLVPILMLTAKNDEFDRVLGLELGADDYMTKPFSPREVVARVKAILRRSQFVKEVEEIDDDITIGSIRIRPDYFEVYKHNELLELTPKEFELLLYLIERQGRVITREHMLNTVWNYEFAGDSRIVDVHISHLRDKLEDNPKKPQLIKTVRGLGYKLERPKEQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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