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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS06005 [old locus tag: NWMN_1064 ]
  • pan locus tag?: SAUPAN003391000
  • symbol: NWMN_RS06005
  • pan gene symbol?: —
  • synonym:
  • product: non-canonical purine NTP pyrophosphatase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS06005 [old locus tag: NWMN_1064 ]
  • symbol: NWMN_RS06005
  • product: non-canonical purine NTP pyrophosphatase
  • replicon: chromosome
  • strand: +
  • coordinates: 1168817..1169404
  • length: 588
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (1168817..1169404) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1064

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
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    481
    541
    ATGAAAGAGATTGTTATTGCATCGAATAATCAAGGGAAAATAAATGACTTTAAAGTAATA
    TTTCCAGATTACCACGTAATAGGTATTTCAGAACTAATACCAGATTTTGATGTGGAAGAA
    ACAGGATCAACATTTGAAGAAAATGCTATATTAAAATCAGAAGCTGCTGCAAAAGCATTG
    AATAAAACGGTCATAGCTGATGACAGTGGACTAGAAGTTTTTGCATTAAATGGTGAGCCA
    GGTATATACTCTGCACGTTATGCTGGTGAAAATAAAAGCGATGAAGCAAATATTGAAAAA
    TTATTAAATAAGCTTGGTAATACAACTGATCGTCGTGCGCAATTTGTTTGTGTCATAAGT
    ATGAGTGGCCCTGATATGGAAACAAAAGTATTTAAAGGTACTGTTTCAGGTGAAATTGCA
    GATGGAAAATATGGCGAAAATGGTTTCGGATATGATCCGATATTTTATGTACCGAAATTA
    GATAAAACCATGGCTCAACTTTCAAAAGAACAAAAAGGGCAAATTAGTCATAGACGAAAT
    GCGATTAATTTACTTCAAGCTTTTCTTGAAGGTGATAAAAATGTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    588

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS06005 [old locus tag: NWMN_1064 ]
  • symbol: NWMN_RS06005
  • description: non-canonical purine NTP pyrophosphatase
  • length: 195
  • theoretical pI: 4.62754
  • theoretical MW: 21403
  • GRAVY: -0.36359

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.1.66?  ExPASy
    XTP/dITP diphosphatase XTP + H2O = XMP + diphosphate dITP + H2O = dIMP + diphosphate ITP + H2O = IMP + diphosphate
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family (TIGR00042; EC 3.6.1.-; HMM-score: 203.2)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Maf (CL0269) Ham1p_like; Ham1 family (PF01725; HMM-score: 188.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Mg2+
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018916
    • TAT(Tat/SPI): 0.000093
    • LIPO(Sec/SPII): 0.000192
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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