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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2374 [new locus tag: NWMN_RS13680 ]
  • pan locus tag?: SAUPAN006049000
  • symbol: NWMN_2374
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2374 [new locus tag: NWMN_RS13680 ]
  • symbol: NWMN_2374
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2611566..2611988
  • length: 423
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAACAAAAAACATGTTTTTATAATTATTGGTGTCATTTTATGTATATGTATAGTTGCA
    TCAGTCATTTATTTAAAAGTGAAATATGACGAAAAAGAAAAACAAAAAGCAATATACTAT
    AAAGAACAACAGGAGCGTATTACACTCTATCTTAAGCATAATACTAAAGAACCCAATACC
    ATCAAAACTGTACATTTCACAAGTTTAAAAAGAGGACCTATGGGCGATGCAGTAATTGAA
    GGTTACATAAATGAAAATAAAGAAGATGATTTTGTTGCATATGGGTCTCCAGAACATAAT
    TATCAATTTGGTGGAAGTTTAATCAAAAGTAAAAATTTAAGCACGTTATTAAAACCAGTA
    CATCAAACCAAATCACCTGATGAGATAAAAAAGGAATTAGAGTCTAAAAAGAACGACCGC
    TAA
    60
    120
    180
    240
    300
    360
    420
    423

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_2374 [new locus tag: NWMN_RS13680 ]
  • symbol: NWMN_2374
  • description: hypothetical protein
  • length: 140
  • theoretical pI: 9.61055
  • theoretical MW: 16201.6
  • GRAVY: -0.617143

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 15.7)
    Cellular processes Cellular processes Adaptations to atypical conditions phage shock protein B (TIGR02976; HMM-score: 13.2)
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 12.8)
  • TheSEED  :
    • FIG01108221: hypothetical protein
  • PFAM:
    no clan defined DUF1433; Protein of unknown function (DUF1433) (PF07252; HMM-score: 134.6)
    and 8 more
    Viral_Beta_CD; Viral Beta C/D like family (PF04530; HMM-score: 15.7)
    DUF1310; Protein of unknown function (DUF1310) (PF07006; HMM-score: 14.9)
    Sec66; Preprotein translocase subunit Sec66 (PF09802; HMM-score: 14.8)
    TrbC_VirB2 (CL0690) T4SS_pilin; Type IV secretion system pilin (PF18895; HMM-score: 13.8)
    no clan defined DUF7299; Family of unknown function (DUF7299) (PF23973; HMM-score: 13.7)
    DUF3377; Domain of unknown function (DUF3377) (PF11857; HMM-score: 12.5)
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 11.7)
    no clan defined PMP1_2; ATPase proteolipid family (PF08114; HMM-score: 7.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.597
    • Cell wall & surface Score: 0.0017
    • Extracellular Score: 0.4012
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 2
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.225666
    • TAT(Tat/SPI): 0.002545
    • LIPO(Sec/SPII): 0.095256
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNKKHVFIIIGVILCICIVASVIYLKVKYDEKEKQKAIYYKEQQERITLYLKHNTKEPNTIKTVHFTSLKRGPMGDAVIEGYINENKEDDFVAYGSPEHNYQFGGSLIKSKNLSTLLKPVHQTKSPDEIKKELESKKNDR

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]