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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2173 [new locus tag: NWMN_RS12560 ]
  • pan locus tag?: SAUPAN005734000
  • symbol: moeA
  • pan gene symbol?: moeA
  • synonym:
  • product: molybdopterin biosynthesis protein MoeA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2173 [new locus tag: NWMN_RS12560 ]
  • symbol: moeA
  • product: molybdopterin biosynthesis protein MoeA
  • replicon: chromosome
  • strand: -
  • coordinates: 2396601..2397860
  • length: 1260
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGTAGTAGAAAAAAGAAACCCAATCCCAGTTAAAGAAGCAATTCAACGTATCGTTAAT
    CAGCAGAGTTCAATGCCGGCAATTACGGTAGCACTTGAAAAAAGTCTAAATCATATCTTA
    GCAGAAGATATTGTAGCTACTTATGATATACCAAGGTTTGATAAATCACCTTATGATGGT
    TTTGCAATTCGCAGTGTTGATTCACAAGGGGCAAGTGGTCAGAATCGCATTGAGTTTAAA
    GTGATTGATCATATTGGTGCAGGTTCAGTTTCTGATAAATTAGTTGGGGATCACGAAGCG
    GTGCGTATTATGACTGGAGCACAAATACCTAATGGCGCAGATGCTGTTGTTATGTTTGAA
    CAAACGATTGAACTAGAAGATACATTTACAATTCGTAAACCATTTTCAAAAAATGAAAAT
    ATATCTTTAAAAGGTGAAGAAACAAAGACAGGCGATGTTGTTCTAAAAAAAGGACAAGTA
    ATTAATCCAGGGGCTATCGCGGTCCTTGCAACATATGGCTATGCAGAGGTTAAAGTTATT
    AAGCAACCGAGTGTCGCTGTTATTGCAACAGGAAGCGAATTATTAGATGTTAATGATGTA
    TTAGAAGATGGAAAAATTCGTAACTCTAATGGCCCAATGATTCGTGCCTTAGCAGAAAAA
    TTAGGTCTTGAAGTTGGTATTTACAAAACACAAAAAGATGATTTAGATAGTGGCATCCAA
    GTCGTTAAAGAAGCTATGGAAAAACATGATATCGTTATTACAACGGGCGGAGTTTCTGTT
    GGAGATTTTGACTATTTACCTGAGATTTATAAGGCTGTAAAGGCGGAAGTGTTATTTAAT
    AAAGTAGCAATGCGTCCTGGTAGCGTAACAACGGTTGCATTTGTAGATGGAAAGTATTTG
    TTTGGATTATCTGGAAATCCATCAGCTTGTTTTACAGGATTTGAACTATTTGTGAAACCA
    GCTGTTAAACATATGTGTGGCGCACTAGAAGTCTTCCCGCAAATAATTAAAGCAACATTA
    ATGGAAGATTTTACCAAGGCAAACCCATTCACACGATTTATACGTGCTAAAGCAACGTTA
    ACAAGTGCTGGAGCTACTGTAGTACCTTCAGGATTCAATAAATCAGGTGCGGTTGTAGCG
    ATTGCACATGCTAACTGTATGGTCATGTTACCAGGAGGGTCACGTGGTTTTAAAGCGGGG
    CATACAGTAGATATTATATTGACTGAATCTGACGCTGCTGAAGAGGAACTTCTTTTATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2173 [new locus tag: NWMN_RS12560 ]
  • symbol: MoeA
  • description: molybdopterin biosynthesis protein MoeA
  • length: 419
  • theoretical pI: 5.50634
  • theoretical MW: 45016.5
  • GRAVY: 0.0575179

⊟Function[edit | edit source]

  • TIGRFAM:
    molybdenum cofactor synthesis domain (TIGR00177; HMM-score: 113.2)
    and 1 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair competence/damage-inducible protein CinA N-terminal domain (TIGR00200; HMM-score: 23.5)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined MoeA_N; MoeA N-terminal region (domain I and II) (PF03453; HMM-score: 139.4)
    and 2 more
    MoCF_biosynth; Probable molybdopterin binding domain (PF00994; HMM-score: 94)
    MoeA_C; MoeA C-terminal region (domain IV) (PF03454; HMM-score: 59.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009777
    • TAT(Tat/SPI): 0.00108
    • LIPO(Sec/SPII): 0.00068
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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