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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1413 [new locus tag: NWMN_RS07975 ]
  • pan locus tag?: SAUPAN004041000
  • symbol: NWMN_1413
  • pan gene symbol?:
  • synonym:
  • product: transcriptional regulator AraC family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1413 [new locus tag: NWMN_RS07975 ]
  • symbol: NWMN_1413
  • product: transcriptional regulator AraC family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1582034..1582927
  • length: 894
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATTGAATTAATTGGAGTGAAAGTTTTGGACGTTATCAAGCAAATACAACAGGCAATT
    GTTTATATTGAAGATCGTTTATTAGAGCCTTTCAATTTGCAAGAATTAAGTGATTACGTT
    GGTCTTTCGCCATACCATCTTGATCAATCATTTAAAATGATTGTCGGCTTATCTCCAGAA
    GCTTATGCACGCGCGCGTAAAATGACACTCGCTGCAAATGATGTGATTAATGGTGCTACA
    CGACTTGTAGATATCGCTAAAAAATATCACTATGCAAATTCAAATGATTTTGCAAATGAT
    TTTAGTGATTTTCACGGCGTATCACCTATTCAAGCCTCTACTAAAAAAGATGAATTACAA
    ATTCAAGAGCGATTATATATCAAATTATCAACTACTGAGAGAGCACCTTATCCATACAGA
    TTAGAAGAGACAGATGATATTTCATTGGTTGGATATGCACGATTTATAGACACTAAGTAT
    TTGTCACATCCTTTTAATGTTCCGGATTTTTTAGAAGACTTGCTCATTGATGGTAAAATT
    AAAGAGTTACGACGATATAATGACGTTAGTCCATTTGAACTATTTGTTATTAGTTGTCCT
    CTTGAAAATGGTTTAGAAATATTTGTAGGTGTACCAAGTGAACGTTATCCTGCACACTTA
    GAAAGTCGATTTTTACCTGGCAAACATTGTGCGAAATTCAATTTACAAGGTGAAATTGAT
    TATGCAACTAATGAAGCTTGGTACTATATTGAATCAAGTTTGCAGTTAACATTGCCATAT
    GAACGAAATGATTTATATGTTGAAGTGTACCCTCTCGATATTTCATTTAATGACCCATTC
    ACTAAAATTCAGCTTTGGATTCCTGTTAAACAGAGTCCTTATGACGAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    894

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_1413 [new locus tag: NWMN_RS07975 ]
  • symbol: NWMN_1413
  • description: transcriptional regulator AraC family protein
  • length: 297
  • theoretical pI: 4.5112
  • theoretical MW: 34373.7
  • GRAVY: -0.282828

Function[edit | edit source]

  • TIGRFAM:
    YSIRK-targeted surface antigen transcriptional regulator (TIGR04094; HMM-score: 35.6)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    SHS2 (CL0319) Cass2; Integron-associated effector binding protein (PF14526; HMM-score: 79.6)
    and 2 more
    HTH (CL0123) HTH_18; Helix-turn-helix domain (PF12833; HMM-score: 45.9)
    HTH_AraC; Bacterial regulatory helix-turn-helix proteins, AraC family (PF00165; HMM-score: 23.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002234
    • TAT(Tat/SPI): 0.000602
    • LIPO(Sec/SPII): 0.000206
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MIELIGVKVLDVIKQIQQAIVYIEDRLLEPFNLQELSDYVGLSPYHLDQSFKMIVGLSPEAYARARKMTLAANDVINGATRLVDIAKKYHYANSNDFANDFSDFHGVSPIQASTKKDELQIQERLYIKLSTTERAPYPYRLEETDDISLVGYARFIDTKYLSHPFNVPDFLEDLLIDGKIKELRRYNDVSPFELFVISCPLENGLEIFVGVPSERYPAHLESRFLPGKHCAKFNLQGEIDYATNEAWYYIESSLQLTLPYERNDLYVEVYPLDISFNDPFTKIQLWIPVKQSPYDED

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]