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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0824 [new locus tag: NWMN_RS04655 ]
  • pan locus tag?: SAUPAN003055000
  • symbol: ppi
  • pan gene symbol?: ppiB
  • synonym:
  • product: cyclophilin type peptidyl-prolyl cis-trans isomerase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_0824 [new locus tag: NWMN_RS04655 ]
  • symbol: ppi
  • product: cyclophilin type peptidyl-prolyl cis-trans isomerase
  • replicon: chromosome
  • strand: +
  • coordinates: 911319..911912
  • length: 594
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGCTAACTATCCACAGTTAAACAAAGAAGTACAACAAGGTGAAATCAAAGTGGTTATG
    CACACAAATAAAGGTGACATGACATTCAAATTATTTCCAAATATTGCACCAAAAACAGTT
    GAAAATTTTGTGACACATGCAAAAAATGGTTATTATGATGGAATCACATTCCACCGTGTC
    ATTAATGACTTCATGATTCAAGGTGGCGATCCAACAGCTACTGGTATGGGTGGCGAAAGT
    ATTTATGGCGGTGCTTTTGAAGATGAATTTTCATTAAATGCATTTAACTTATATGGCGCA
    TTATCAATGGCTAACTCAGGACCTAATACTAATGGTTCACAATTTTTCATTGTTCAAATG
    AAAGAAGTACCTCAAAATATGTTAAGTCAACTTGCAGATGGTGGCTGGCCTCAACCAATC
    GTTGATGCATATGGCGAAAAGGGTGGTACACCATGGTTAGATCAAAAACATACAGTATTC
    GGTCAAATCATTGATGGTGAAACTACATTAGAAGATATTGCAAATACAAAAGTGGGACCA
    CAAGATAAACCACTTCATGATGTTGTAATTGAATCTATTGATGTTGAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    594

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_0824 [new locus tag: NWMN_RS04655 ]
  • symbol: Ppi
  • description: cyclophilin type peptidyl-prolyl cis-trans isomerase
  • length: 197
  • theoretical pI: 4.29012
  • theoretical MW: 21619.1
  • GRAVY: -0.380711

⊟Function[edit | edit source]

  • reaction:
    EC 5.2.1.8?  ExPASy
    Peptidylprolyl isomerase Peptidylproline (omega=180) = peptidylproline (omega=0)
  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Cyclophil-like (CL0475) Pro_isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD (PF00160; HMM-score: 161.7)
    and 1 more
    TPR (CL0020) CRM1_C; CRM1 C terminal (PF08767; HMM-score: 13.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011423
    • TAT(Tat/SPI): 0.000242
    • LIPO(Sec/SPII): 0.00117
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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