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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002688
- pan locus tag?: SAUPAN006464000
- symbol: JSNZ_002688
- pan gene symbol?: —
- synonym:
- product: HdeD family acid-resistance protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002688
- symbol: JSNZ_002688
- product: HdeD family acid-resistance protein
- replicon: chromosome
- strand: -
- coordinates: 2706630..2707142
- length: 513
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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121
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421
481ATGGCAAAAGGAAACCAAGGTATTAAATGGTCTAGTTTAATAATGGGTGTATTATTATTA
ATGTTGGCAGTCGTTATTTTTACATTTCCAATTGAAAATTTTTATGCTATTACCTGGTTG
ATTGGACTGTTTGTATTAATTAACGGTGTGATTCAAATCATTTACCGTAGAAAAGCAAAA
GCTTTAGTAGGTGGTAACCAAAATTGGATTCTGTTTATGGGGATTGTAGATATTCTCTTT
GGTCTTATTGTCATTTTTAATGTTGGCGCTAGCTCGGCATTTTTTATCTACATGTTTGCA
TTCTGGTTCATTTTTAGTTCTATTGCAGGATTATTTACGTTTACGGGTAGTGGTAGCTTA
AAACTAATTTCAGTGATTTTTAATTTATTAGGTATTGTTTTCGGTGTCATTTTATTATTT
AATCCATTAATGGGTATCGTCTTTATTTCGACGATGATTGCTATTGCATTTGTATTCGTA
GGTGTCATTTATGTTGTAGATGCACTTGCTTAA60
120
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480
513
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002688
- symbol: JSNZ_002688
- description: HdeD family acid-resistance protein
- length: 170
- theoretical pI: 10.1473
- theoretical MW: 18714.7
- GRAVY: 1.55647
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: no clan defined DUF308; Short repeat of unknown function (DUF308) (PF03729; HMM-score: 73.5)and 1 moreDUF2070; Predicted membrane protein (DUF2070) (PF09843; HMM-score: 7.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 6
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.9985
- Cell wall & surface Score: 0
- Extracellular Score: 0.0015
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004871
- TAT(Tat/SPI): 0.000192
- LIPO(Sec/SPII): 0.00552
- predicted transmembrane helices (TMHMM): 6
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MAKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLFVLINGVIQIIYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFWFIFSSIAGLFTFTGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFVFVGVIYVVDALA
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: SigB (activation) regulon
SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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