PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_002602
• pan locus tag^?: SAUPAN006323000
• symbol: JSNZ_002602
• pan gene symbol^?: citM
• synonym:
• product: CitMHS family transporter

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_002602
• symbol: JSNZ_002602
• product: CitMHS family transporter
• replicon: chromosome
• strand: -
• coordinates: 2608087..2609457
• length: 1371
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  
  ATGAATAGTGATAATATGTGGTTAACAGTAATGGGGCTCATTATTATTATTTCAATTGTA
  GGTTTACTCATTGCCAAAAAGATAAATCCAGTTGTAGGTATGACAATCATACCTTGCTTA
  GGGGCAATGATTTTAGGATATAGTGTGACAGATTTGGTTGGATTTTTTGCTAAAGGGTTA
  GACCAAGTCATCAACGTTGTTATTATGTTTATCTTTGCCATTATTTTCTTTGGCATCATG
  AACGATAGTGGTTTATTCAAGCCGCTTGTCAAACGCTTAATATTAATGACACGAGGCAAT
  GTCGTCATTGTCTGTGCAATGACAGCTTTAATTGGCACAATAGCCCAATTAGATGGTGCC
  GGTGCGGTAACATTTTTGCTTTCTATTCCTGCATTATTACCTTTATATAAAGCGTTAAAT
  ATGAATAAATATTTATTGATTCTACTATTAGCATTAAGTGCTGCAATTATGAACATGGTA
  CCTTGGGGAGGTCCGATGGCACGTGTAGCTGCAGTGTTAAAAGCCAAAAGTGTCAATGAA
  TTATGGTATGGATTAATTCCTATTCAAATAATAGGATTCATTCTTGTTATGTTGTTTGCG
  GTATATCTTGGATTTAAAGAACAAAAACGTATCAAAAAAGCAATTGCTAGCAATGAATTA
  CCGCAAACACAAGATATAGATGTACATAAATTAGTTGAAGTATATGAACGAGATCAAGAT
  GTAAGGTTTCCTGTAAAAGGACGTGCACGAACAAAACCATGGATAAAATGGGTGAATACA
  GCTTTAACTTTAGCTGTTATTCTAGCGATGTTAATAAATATTGCGCCACCTGAATTTGCA
  TTCATGATAGGTGTTTCGTTGGCACTTGTTATTAATTTTAAATCAGTGGATGAACAAATG
  GAACGATTAAGAGCGCATGCGCCGAATGCATTAATGATGGCTGCAGTGATTATTGCAGCA
  GGTATGTTTTTAGGTGTACTAAATGAAACCGGTATGCTTAAAGCGATTGCGACCAATTTA
  ATCAAAGTGATTCCTGCAGAAGTAGGACCATACTTGCATATTATTGTAGGTTTACTTGGC
  GTACCATTAGATTTACTAACTAGCACAGACGCTTATTATTTTGCTGTGTTACCGATTGTC
  GAACAAACAGCAGGGCAATTTGGTGTACCGTCTGTATCAACAGCTTATTCAATGGTCATA
  GGGAATATTATAGGTACATTTGTCAGCCCATTTTCACCAGCCTTATGGTTGGCAATTGGT
  TTAGCAGAGGCAAACATGGGCACGTATATTAAGTATGCATTCTTTTGGATTTGGGGATTC
  GCCATCGTTATGTTAGTAATTGCAATGTTGATGGGCATTGTGACGATTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1371
  

⊟Protein

⊟General

• locus tag: JSNZ_002602
• symbol: JSNZ_002602
• description: CitMHS family transporter
• length: 456
• theoretical pI: 9.61179
• theoretical MW: 49638
• GRAVY: 0.976097

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids citrate transporter (TIGR00784; HMM-score: 284)
  and 1 more
  Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 13.3)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  IT (CL0182) CitMHS; Citrate transporter (PF03600; HMM-score: 125.4)
  and 8 more
  DctM; Tripartite ATP-independent periplasmic transporter, DctM component (PF06808; HMM-score: 27.2)
  DcuC; C4-dicarboxylate anaerobic carrier (PF03606; HMM-score: 24.2)
  Na_H_antiporter; Na+/H+ antiporter family (PF03553; HMM-score: 22.8)
  Na_H_antiport_2; Na+-H+ antiporter family (PF13726; HMM-score: 16.6)
  no clan defined Caudo_bapla_N; Lactophage receptor-binding protein N-terminal shoulder domain (PF20747; HMM-score: 13.6)
  Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 11.1)
  RNF152_C; E3 ubiquitin-protein ligase RNF152 C-terminus (PF19325; HMM-score: 10.5)
  LapA_dom; Lipopolysaccharide assembly protein A domain (PF06305; HMM-score: 8.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 12
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9999
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0001
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.03563
  • TAT(Tat/SPI): 0.000627
  • LIPO(Sec/SPII): 0.011641
• predicted transmembrane helices (TMHMM): 12

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MNSDNMWLTVMGLIIIISIVGLLIAKKINPVVGMTIIPCLGAMILGYSVTDLVGFFAKGLDQVINVVIMFIFAIIFFGIMNDSGLFKPLVKRLILMTRGNVVIVCAMTALIGTIAQLDGAGAVTFLLSIPALLPLYKALNMNKYLLILLLALSAAIMNMVPWGGPMARVAAVLKAKSVNELWYGLIPIQIIGFILVMLFAVYLGFKEQKRIKKAIASNELPQTQDIDVHKLVEVYERDQDVRFPVKGRARTKPWIKWVNTALTLAVILAMLINIAPPEFAFMIGVSLALVINFKSVDEQMERLRAHAPNALMMAAVIIAAGMFLGVLNETGMLKAIATNLIKVIPAEVGPYLHIIVGLLGVPLDLLTSTDAYYFAVLPIVEQTAGQFGVPSVSTAYSMVIGNIIGTFVSPFSPALWLAIGLAEANMGTYIKYAFFWIWGFAIVMLVIAMLMGIVTI

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications