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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002543
  • pan locus tag?: SAUPAN006227000
  • symbol: crtQ
  • pan gene symbol?: crtQ
  • synonym:
  • product: 4,4'-diaponeurosporenoate glycosyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002543
  • symbol: crtQ
  • product: 4,4'-diaponeurosporenoate glycosyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 2552356..2553483
  • length: 1128
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAAATGGTTATCACGAATATTAACAGTAATAGTGACCATGTCTATGGCGTGTGGTGCA
    TTGATATTTAATCGTAGACATCAGCTAAAGGCGAAAACGCTGAACTTCAATCATAAAGCA
    TTAACAATTATTATTCCGGCTAGAAACGAAGAAAAAAGAATAGGTCATTTACTACATTCG
    ATAATACAACAGCAAGTTCCAGTAGATGTCATTGTTATGAATGACGGATCGACAGATGAA
    ACAGCACGTGTAGCACGTTCATATGGTGCGACTGTAGTAGATGTTGTTGATGATACTGAC
    GGCAAATGGTATGGGAAATCACATGCTTGTTATCAAGGTGTGACGCATGCATGTACGAAT
    CGTATTGCCTTTGTAGATGCTGATGTAACTTTCTTAAGGAAAGATGCTGTTGAAACGTTG
    ATTAATCAGTATCAATTACAAGGTGAAAAAGGATTGTTAAGCGTACAGCCTTATCATATA
    ACAAAGCGTTTCTACGAAGGGTTTTCAGCAATATTTAATTTAATGACAGTCGTTGGTATG
    AATGTATTTTCTACCTTAGACGACGGTCGGACTAACCAGCATGCATTTGGACCGGTGACA
    TTAACAAATAAAGAAGATTATTATGCAACTGGAGGTCATAAAAGTGCAAACCGTCATATT
    ATTGAAGGATTTGCTTTAGGAAGTGCATATACTTCACAATCATTGCCCGTAACAGTTTAT
    GAAGGATTTCCATTTGTTGCATTTCGCATGTATCAAGAAGGATTTCAGTCATTACAAGAA
    GGATGGACAAAGCATTTGTCAACTGGGGCAGGTGGCACAAAGCCTAAGATCATGACAGCA
    ATTGTGTTGTGGTTGTTCGGTTCTATAGCGAGTATTTTAGGGTTATGTCTTAGTTTAAAA
    TATCGCCAAATGTCTGTAAGAAAAATGGTAGCACTTTACTTGAGCTATACTACACAATTT
    ATTTATCTGCATCGAAGGGTCGGCCAATTTTCTAATTTATTAATGGTATGTCATCCATTG
    TTATTTATGTTTTTTACTAAAATTTTCATCCAATCTTGGAAAGAAACGCATCGTTATGGT
    GTAGTTGAATGGAAAGGTCGTCAATATTCTATATCTAAAGAACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1128

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002543
  • symbol: CrtQ
  • description: 4,4'-diaponeurosporenoate glycosyltransferase
  • length: 375
  • theoretical pI: 9.77608
  • theoretical MW: 42544.9
  • GRAVY: -0.044

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.1.-?  ExPASy
  • TIGRFAM:
    hopene-associated glycosyltransferase HpnB (TIGR03469; HMM-score: 60.3)
    and 8 more
    Unknown function Enzymes of unknown specificity transferase 2, rSAM/selenodomain-associated (TIGR04283; EC 2.-.-.-; HMM-score: 47.4)
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 45.9)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 42.4)
    mycofactocin system glycosyltransferase (TIGR03965; HMM-score: 42.2)
    putative glycosyltransferase, exosortase G-associated (TIGR03111; HMM-score: 29.9)
    hopanoid biosynthesis associated glycosyl transferase protein HpnI (TIGR03472; HMM-score: 15)
    Hypothetical proteins Conserved TIGR00454 family protein (TIGR00454; HMM-score: 13.1)
    glycosyltransferase domain (TIGR04440; EC 2.-.-.-; HMM-score: 12.8)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    GT-A (CL0110) Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 64.1)
    and 6 more
    Glyco_tranf_2_3; Glycosyltransferase like family 2 (PF13641; HMM-score: 39.7)
    Glyco_tranf_2_2; Glycosyltransferase like family 2 (PF10111; HMM-score: 37.4)
    NTP_transf_3; MobA-like NTP transferase domain (PF12804; HMM-score: 21.8)
    Glyco_transf_21; Glycosyl transferase family 21 (PF13506; HMM-score: 16.1)
    Glyco_tranf_2_4; Glycosyl transferase family 2 (PF13704; HMM-score: 13.2)
    C2H2-zf (CL0361) zf-WIZ; Zinc finger found in WIZ protein (PF23015; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0044
    • Cytoplasmic Membrane Score: 0.9948
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0007
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 17 aa
    • SP(Sec/SPI): 0.019225
    • TAT(Tat/SPI): 0.003522
    • LIPO(Sec/SPII): 0.936878
    • Cleavage Site: CS pos: 17-18. SMA-CG. Pr: 0.9397
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKETHRYGVVEWKGRQYSISKEQ

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: SigB (activation) regulon
    SigB(sigma factor)controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026)   other strains

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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