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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002540
  • pan locus tag?: SAUPAN006224000
  • symbol: JSNZ_002540
  • pan gene symbol?: —
  • synonym:
  • product: aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002540
  • symbol: JSNZ_002540
  • product: aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
  • replicon: chromosome
  • strand: -
  • coordinates: 2548355..2549509
  • length: 1155
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGATCTCTAACAAATTAGCAAATATCCCTGATAGTTATTTCGGGAAAACGATGGGACGT
    AAAATCGAATATGGACCATTGCCATTAATTAATATGGCAGTTGGAATCCCTGATGGGCCC
    ACGCCACAAGGTATTATTGATCATTTTCAAAAAGCACTAACTATTCCTGAAAATCAAAAA
    TATGGTGCTTTTCATGGTAAAGAAGCGTTCAAGCAAGCTATTGTAGATTTTTATCAAAGA
    CAATATAATGTGACGTTAGATAAAGAAGATGAAGTATGCATTTTATATGGTACAAAAAAT
    GGATTAGTGGCAGTACCAACATGTGTTATCAATCCAGGAGACTATGTATTACTACCTGAT
    CCAGGCTACACGGACTATTTAGCAGGTGTACTTTTAGCTGATGGCAAGCCAGTTCCGCTT
    AATTTAGAACCGCCACATTATTTGCCAGATTGGTCCACAGTTGATTCACAAATAATAGAT
    AAAACAAAACTCATTTATTTAACGTATCCAAATAATCCAACTGGATCGACAGCTACGAAA
    GAAGTTTTTGATGAAGCGATAGCTAAATTTAAAGATACAGACACTAAAATCGTGCATGAT
    TTTGCTTATGGTGCTTTCGGTTTCGACGCTAAAAATCCTAGTATACTTGCTTCGGAAAAT
    GGGAAAGATGTTGCGATTGAAATTTATTCCTTGTCTAAAGGTTATAACATGTCAGGTTTT
    AGAGTCGGTTTTGCAGTTGGTAATAAAGATATGATTCAAGCTTTGAAAAAGTACCAAACG
    CACACAAATGCTGGGATGTTTGGTGCATTACAAGATGCCGCAATATATGCTTTGAATCAT
    TATGATGATTTTTTAGAAGAACAAAGCAATGTATTTAAAACACGTCGTGACCGATTCGAA
    GCCATGCTTGCAAAAGCTGATTTGCCATTTGTTCATGCTAAAGGTGGCATATATGTATGG
    TTGGAAACACCGCCTGGTTATGACAGCGAGCAATTTGAGCAATTTTTAGTGCAAGAGAAG
    TCAATACTTGTTGCTCCAGGGAAACCATTTGGAGAGAATGGTAATCGTTATGTGAGAATT
    TCATTGGCGTTAGATGACCAGAAATTAGATGAAGCTGCAATAAGATTAACAGAACTAGCA
    TATTTATATGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1155

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002540
  • symbol: JSNZ_002540
  • description: aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
  • length: 384
  • theoretical pI: 4.84961
  • theoretical MW: 42791.3
  • GRAVY: -0.275

⊟Function[edit | edit source]

  • TIGRFAM:
    LL-diaminopimelate aminotransferase (TIGR03540; EC 2.6.1.83; HMM-score: 368.8)
    and 14 more
    succinyldiaminopimelate transaminase (TIGR03537; EC 2.6.1.17; HMM-score: 198)
    succinyldiaminopimelate transaminase (TIGR03539; EC 2.6.1.17; HMM-score: 167.3)
    succinyldiaminopimelate transaminase (TIGR03538; EC 2.6.1.17; HMM-score: 156.7)
    LL-diaminopimelate aminotransferase (TIGR03542; EC 2.6.1.83; HMM-score: 115.2)
    putative C-S lyase (TIGR04350; EC 4.4.-.-; HMM-score: 105.9)
    Metabolism Amino acid biosynthesis Histidine family histidinol-phosphate transaminase (TIGR01141; EC 2.6.1.9; HMM-score: 101.6)
    tyrosine/nicotianamine family aminotransferase (TIGR01265; HMM-score: 100.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin threonine-phosphate decarboxylase (TIGR01140; EC 4.1.1.81; HMM-score: 96.3)
    Cellular processes Cellular processes Biosynthesis of natural products capreomycidine synthase (TIGR03947; HMM-score: 93.4)
    Metabolism Energy metabolism Amino acids and amines tyrosine aminotransferase (TIGR01264; EC 2.6.1.5; HMM-score: 91.9)
    beta-methylarginine biosynthesis bifunctional aminotransferase (TIGR04544; EC 2.6.-.-; HMM-score: 90.8)
    enduracididine biosynthesis enzyme MppQ (TIGR04461; EC 2.-.-.-; HMM-score: 69.6)
    Metabolism Energy metabolism Amino acids and amines aspartate 4-decarboxylase (TIGR03801; EC 4.1.1.12; HMM-score: 24.4)
    enduracididine biosynthesis enzyme MppP (TIGR04462; EC 2.-.-.-; HMM-score: 13.7)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    PLP_aminotran (CL0061) Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 219.1)
    and 3 more
    Alliinase_C; Allinase (PF04864; HMM-score: 24.6)
    DegT_DnrJ_EryC1; DegT/DnrJ/EryC1/StrS aminotransferase family (PF01041; HMM-score: 17.6)
    SH3 (CL0010) PAZ; PAZ domain (PF02170; HMM-score: 15.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9961
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0034
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011945
    • TAT(Tat/SPI): 0.00074
    • LIPO(Sec/SPII): 0.003186
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MISNKLANIPDSYFGKTMGRKIEYGPLPLINMAVGIPDGPTPQGIIDHFQKALTIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSTVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTELAYLYE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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