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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002427
- pan locus tag?: SAUPAN006007000
- symbol: JSNZ_002427
- pan gene symbol?: pnbA
- synonym:
- product: carboxylesterase family protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002427
- symbol: JSNZ_002427
- product: carboxylesterase family protein
- replicon: chromosome
- strand: +
- coordinates: 2427852..2429204
- length: 1353
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1321ATGAAGATTAATACTACAGGTGGTCAAATTCATGGTATTACACAAGATGGTTTAGATATC
TTCTTAGGCATTCCTTATGCAGAACCACCAGTTCATGACAATCGCTTTAAACATTCTACG
TTAAAAACACAATGGTCAGAGCCAATTGATGCAACTGAAATACAACCCATCCCACCGCAA
CCAGACAACAAATTAGAAGATTTTTTCTCCTCACAATCTACAACTTTTACTGAACATGAA
GACTGTTTATATCTAAATATTTGGAAACAACATAATGATCAGACGAAGAAACCTGTCATC
ATTTATTTTTATGGTGGTAGTTTTGAAAATGGTCATGGTACAGCCGAACTCTATCAACCA
GCACATTTAGTACAAAATAACGACATTATCGTTATTACATGCAATTATCGTTTAGGCGCA
TTAGGATATTTAAACTGGTCATATTTTAATAAAGATTTTCATTCCAATAATGGCCTTTCA
GATCAAATCAATGTCATAAAATGGGTGCATCAATTTATTGAATCCTTCGGTGGCGACGCT
AATAACATTACTTTAATGGGTCAGTCTGCAGGCAGTATGAGCATTTTGACTTTACTTAAA
ATACCTGACATTGAGCCATACTTCCATAAAGTCGTTCTACTAAGTGGCGCACTACGATTA
GACACCCTTGAGAGTGCACGCAATAAAGCACAACATTTCCAAAAAATGATGCTCGATTAT
TTAGATACAGATGATGTTACATCATTATCGACAAATGATATTCTTATGCTGATGGCGAAG
CTAAAACAATCTCGAGGACCTTCTAAAGGGCTTGATTTAATATATGCGCCTATTAAAACA
GATTATATACAAAATAATTATCCAACAACGAAACCAATTTTTGCATGTTATACAAAAGAT
GAAGGCGATATTTATATTACTAGTGAACAGAAAAAATTATCGCCGCAACGCTTTATCGAC
ATTATGGAATTAAATGATATTCCTTTAAAATACGAAGATGTTCAGACGGCGAAGCAACAA
TCTTTAGCGATTACACATTGTTATTTCAAACAGCCGATGAAGCAATTTTTACAACAACTC
AATATACAAGATTCAAACGCACAACTATGGCTTGCTGAATTTGCATGGCATGATACTTCT
AACGCACACTATCGCAGTGCTTACCATATTCTAGATATGGTGTTTTGGTTCGGAAACTTA
CAAATATTAGCAGCACATCAATATCCAACAACTGCTCACCTTAAATTTTTAAGTCGACAA
ATGCAAAATGATTTAGCTAATTTTGCTAAAAGCGGTAAAATGCCTTGGCCGATGTATCAT
AATGAACGTCGCTATTATCGCACATATCAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002427
- symbol: JSNZ_002427
- description: carboxylesterase family protein
- length: 450
- theoretical pI: 6.60126
- theoretical MW: 51994.6
- GRAVY: -0.467111
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: AB_hydrolase (CL0028) COesterase; Carboxylesterase family (PF00135; HMM-score: 251.7)and 4 moreBD-FAE; BD-FAE (PF20434; HMM-score: 33.3)Abhydrolase_3; alpha/beta hydrolase fold (PF07859; HMM-score: 30)Peptidase_S9; Prolyl oligopeptidase family (PF00326; HMM-score: 20)Say1_Mug180; Steryl acetyl hydrolase (PF10340; HMM-score: 14.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.67
- Cytoplasmic Membrane Score: 0.01
- Cellwall Score: 0.15
- Extracellular Score: 0.17
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.7169
- Cytoplasmic Membrane Score: 0.0033
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.2794
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.01266
- TAT(Tat/SPI): 0.001294
- LIPO(Sec/SPII): 0.002138
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MKINTTGGQIHGITQDGLDIFLGIPYAEPPVHDNRFKHSTLKTQWSEPIDATEIQPIPPQPDNKLEDFFSSQSTTFTEHEDCLYLNIWKQHNDQTKKPVIIYFYGGSFENGHGTAELYQPAHLVQNNDIIVITCNYRLGALGYLNWSYFNKDFHSNNGLSDQINVIKWVHQFIESFGGDANNITLMGQSAGSMSILTLLKIPDIEPYFHKVVLLSGALRLDTLESARNKAQHFQKMMLDYLDTDDVTSLSTNDILMLMAKLKQSRGPSKGLDLIYAPIKTDYIQNNYPTTKPIFACYTKDEGDIYITSEQKKLSPQRFIDIMELNDIPLKYEDVQTAKQQSLAITHCYFKQPMKQFLQQLNIQDSNAQLWLAEFAWHDTSNAHYRSAYHILDMVFWFGNLQILAAHQYPTTAHLKFLSRQMQNDLANFAKSGKMPWPMYHNERRYYRTYQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: SigB (activation) regulon
SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]