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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002146
  • pan locus tag?: SAUPAN005567000
  • symbol: JSNZ_002146
  • pan gene symbol?: htsA
  • synonym:
  • product: Fe(3+) dicitrate ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002146
  • symbol: JSNZ_002146
  • product: Fe(3+) dicitrate ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2162753..2163736
  • length: 984
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGAGGTCTAAAAACTTTTAGTATATTGGGATTAATAGTTGCCTTACTTTTAGTTGCA
    GGTTGTGGTAATACGGATAATTCAAGTAAAAAAGAATCATCAACTAAAGATACTATTTCG
    GTAAAAGATGAAAATGGTACAGTAAAAGTACCTAAAGATGCAAAACGTATCGTTGTATTA
    GAGTACTCATTTGCAGATGCATTAGCAGCATTAGACGTTAAACCAGTTGGTATTGCTGAT
    GATGGTAAGAAAAAACGTATCATTAAACCAGTTAGAGAAAAAATTGGGGATTATACTTCT
    GTAGGTACACGTAAACAGCCAAACTTAGAGGAAATTAGTAAATTAAAACCGGATTTAATT
    ATCGCTGATAGCAGTAGACATAAAGGTATTAATAAAGAATTAAACAAAATTGCACCAACA
    TTATCATTAAAGAGTTTTGATGGAGACTACAAACAAAATATTAATTCGTTCAAAACAATT
    GCTAAAGCTTTAAATAAAGAAAAAGAAGGCGAAAAACGTCTTGCTGAGCATGATAAATTA
    ATCAATAAGTATAAAGATGAAATTAAATTTGATAGAAATCAAAAAGTGCTTCCAGCAGTA
    GTTGCTAAAGCTGGTTTATTAGCACATCCAAACTATTCATATGTTGGACAATTTTTAAAC
    GAACTAGGATTTAAAAATGCATTAAGTGACGATGTAACAAAAGGTTTAAGTAAATATTTG
    AAAGGACCTTACTTACAATTAGACACTGAACATTTAGCTGATTTAAATCCAGAGCGTATG
    ATCATTATGACAGATCATGCTAAAAAAGATTCTGCTGAATTCAAGAAGTTACAAGAAGAT
    GCAACATGGAAAAAGTTGAATGCAGTTAAAAATAATCGCGTGGATATTGTTGACCGTGAT
    GTTTGGGCAAGATCTCGTGGCTTAATTTCTTCTGAAGAAATGGCTAAAGAACTTGTTGAA
    TTATCAAAAAAAGAACAAAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    984

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002146
  • symbol: JSNZ_002146
  • description: Fe(3+) dicitrate ABC transporter substrate-binding protein
  • length: 327
  • theoretical pI: 10.05
  • theoretical MW: 36576.9
  • GRAVY: -0.569113

⊟Function[edit | edit source]

  • TIGRFAM:
    heme ABC transporter, heme-binding protein isdE (TIGR03659; HMM-score: 95.6)
    and 2 more
    putative ABC transporter PGF-CTERM-modified substrate-binding protein (TIGR04281; HMM-score: 15.7)
    proposed F420-0 ABC transporter, periplasmic F420-0 binding protein (TIGR03868; HMM-score: 13.4)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Chelatase (CL0043) Peripla_BP_2; Periplasmic binding protein (PF01497; HMM-score: 116.5)
    and 4 more
    no clan defined DUF6556; Family of unknown function (DUF6556) (PF20193; HMM-score: 15.3)
    OML_zippers (CL0590) FadA; Adhesion protein FadA (PF09403; HMM-score: 15.2)
    no clan defined CCDC66; Coiled-coil domain-containing protein 66 (PF15236; HMM-score: 14.1)
    LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 10.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 9.68
    • Cellwall Score: 0.17
    • Extracellular Score: 0.16
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9883
    • Cell wall & surface Score: 0.0044
    • Extracellular Score: 0.0073
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 21 aa
    • SP(Sec/SPI): 0.000436
    • TAT(Tat/SPI): 0.000177
    • LIPO(Sec/SPII): 0.999108
    • Cleavage Site: CS pos: 21-22. VAG-CG. Pr: 0.9998
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRGLKTFSILGLIVALLLVAGCGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIADDGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTIAKALNKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYLKGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVELSKKEQK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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