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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_001989
- pan locus tag?: SAUPAN005275000
- symbol: JSNZ_001989
- pan gene symbol?: agrB
- synonym:
- product: accessory gene regulator AgrB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_001989
- symbol: JSNZ_001989
- product: accessory gene regulator AgrB
- replicon: chromosome
- strand: +
- coordinates: 2003643..2004206
- length: 564
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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481
541TTGAATTATTTTGATAACAAAATTGACCAGTTTGCCACGTATCTTCAAAAGAGAAATAAC
TTAGATCATATTCAATTTTTGCAAGTACGATTAGGGATGCAGGTCTTAGCTAAAAATATA
GGTAAATTAATTGTTATGTATACTATTGCCTATATTTTAAACATTTTTATCTTCACTTTA
ATTACTAATATATCGTTTTATCTAATTAGAAGGTATGCACATGGTGCACATGCACCTTCA
TCTTTTTGGTGTTATATAGAAAGCATTACACTTTTTATTGTGCTACCTCTATTAGTATTG
CATTTTCATATTAATGAAACACTAATGATGTTTTTAGCATTAATAAGTGTTGGAGTAGTG
ATTATATATGCACCTGCAGCCACTAAGAAGAAGCCTATCCCAGCGAGGCTTGTAAAGCAA
AAAAGATATTTTTCAATTATAATTAGTACAATTCTTTTCATTATCACACTTTTTGTAAAA
GAACCATATACCCAATTTATTCAACTGGGTATTATTATACAAGCTATTACATTACTACCA
ATATACTATTCAAAGGAGGACTAA60
120
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564
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_001989
- symbol: JSNZ_001989
- description: accessory gene regulator AgrB
- length: 187
- theoretical pI: 10.0232
- theoretical MW: 21786.1
- GRAVY: 0.665775
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: no clan defined AgrB; Accessory gene regulator B (PF04647; HMM-score: 113.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 5
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0002
- Cytoplasmic Membrane Score: 0.999
- Cell wall & surface Score: 0
- Extracellular Score: 0.0008
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002647
- TAT(Tat/SPI): 0.000092
- LIPO(Sec/SPII): 0.026483
- predicted transmembrane helices (TMHMM): 5
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFIFTLITNISFYLIRRYAHGAHAPSSFWCYIESITLFIVLPLLVLHFHINETLMMFLALISVGVVIIYAPAATKKKPIPARLVKQKRYFSIIISTILFIITLFVKEPYTQFIQLGIIIQAITLLPIYYSKED
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulators: AgrA (activation) regulon, CodY (repression) regulon
AgrA (TF) important in Virulence, Quorum sensing; transcription unit predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) CodY (TF) important in Amino acid metabolism; transcription unit predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026)
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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