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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001956
  • pan locus tag?: SAUPAN004958000
  • symbol: JSNZ_001956
  • pan gene symbol?: —
  • synonym:
  • product: beta-propeller fold lactonase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001956
  • symbol: JSNZ_001956
  • product: beta-propeller fold lactonase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1971945..1972973
  • length: 1029
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGACAAATGGATATATTGGTTCTTACACTAAAAAGAATGGTAAAGGGATTTATCGTTTT
    GAATTAAACGAAAATCAGTCACGTATTGATTTATTAGAAACAGGATTTGAATTAGAAGCG
    TCTACATATTTGGTGCGTAATAATGAAGTTTTATATGGAATCAACAAAGAAGGAGAACAA
    TGCGGTGTTGCAAGTTTGAAAATTGATGACAATGGTGAATTGCATTTATTAAATAAATGT
    TTGTCTTCAAAAGCTGGTACAGGTTGTTATGTATCGATTTCAGAAGATAAACGATATTTA
    TTTGAAGCGGTATATGGTGCTGGCATCATACGTATGTATGAATTAAATACGCACACAGGT
    GAAATTATACGTCTAATTCAAGAACTTGCACATGATTTTCCAACAGGTACACATGAAAGA
    CAAGATCATCCACACGCACATTATATTAATCAAACTCCAGATGGTAAGTACGTTGCAGTA
    ACAGATTTAGGTGCTGATCGTATCGTTACTTATAAATTTGATGACAACGGGTTTGAATTT
    TATAAAGAATCTTTATTTAAAGATAGTGATGGGACAAGACATATTGAATTTCATGATAAT
    GGAAAATTTGCTTATGTCGTACACGAATTATCAAATACTGTGAGTGTTGCAGAATATAAT
    GACGGTAAATTTGAAGAGCTCGAGCGTCATTTAACAATTCCTGAAAACTTTGATGGAGAT
    ACTAAACTTGCAGCAGTGCGTTTATCTCATGATCAACAATTCTTATATGTATCTAATAGA
    GGGCATGATAGCATTGCAATTTTTAAAGTTCTTGATAATGGTCAACACTTAGAACTAGTA
    ACAATTACTGAAAGTGGTGGTCAATTCCCAAGAGATTTTAATATTGCCTCATCAGATGAC
    CTTTTAGTTTGTGCTCATGAGCAAGGAGATTCAGTTGTAACTGTTTTCGAAAGAAATAAA
    GAAACAGGTAAAATTACGCTATGTGATAACACTCGTGTAGCATCTGAAGGTGTATGTGTC
    ATATTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1029

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001956
  • symbol: JSNZ_001956
  • description: beta-propeller fold lactonase family protein
  • length: 342
  • theoretical pI: 4.83508
  • theoretical MW: 38546.5
  • GRAVY: -0.460234

⊟Function[edit | edit source]

  • TIGRFAM:
    PQQ-dependent catabolism-associated beta-propeller protein (TIGR03866; HMM-score: 25.5)
    and 1 more
    40-residue YVTN family beta-propeller repeat (TIGR02276; HMM-score: 14.4)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Beta_propeller (CL0186) Lactonase; Lactonase, 7-bladed beta-propeller (PF10282; HMM-score: 381.2)
    and 1 more
    SBP56; 56kDa selenium binding protein (SBP56) (PF05694; HMM-score: 17.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9965
    • Cytoplasmic Membrane Score: 0.0006
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0026
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003768
    • TAT(Tat/SPI): 0.00012
    • LIPO(Sec/SPII): 0.000375
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLETGFELEASTYLVRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFEAVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAVTDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAEYNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQHLELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERNKETGKITLCDNTRVASEGVCVIF

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: LexA (repression) regulon
    LexA(TF)important in SOS response;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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