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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001950
  • pan locus tag?: SAUPAN004951000
  • symbol: JSNZ_001950
  • pan gene symbol?: sdcS
  • synonym:
  • product: SLC13 family permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001950
  • symbol: JSNZ_001950
  • product: SLC13 family permease
  • replicon: chromosome
  • strand: -
  • coordinates: 1965250..1966812
  • length: 1563
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGCTTATTTCAATCAACATCAATCAATGATATCGAAAAGGTATTTAACATTCTTTTCA
    AAATCAAAGAAAAAGAAACCGTTTAGTGCGGGACAACTTATTGGACTAATATTAGGTCCA
    TTACTTTTCCTATTAACATTATTGTTCTTTCATCCACAAGACTTACCTTGGAAAGGCGTA
    TATGTCTTAGCGATTACTTTATGGATTGCGACTTGGTGGATTACTGAAGCAATTCCTATT
    GCAGCAACGAGCTTATTACCAATTGTGTTATTACCATTAGGTCACATACTTACACCAGAA
    CAAGTATCATCCGAATATGGCAATGATATTATCTTTTTGTTTTTAGGTGGATTTATTTTG
    GCAATTGCAATGGAAAGATGGAATTTACATACGAGAGTAGCTTTGACTATTATTAATTTA
    ATTGGTGCAAGCACTTCAAAAATATTACTTGGATTCATGGTGGCAACAGGATTCTTATCT
    ATGTTTGTATCGAACACTGCAGCTGTAATGATTATGATTCCGATTGGTTTAGCAATTATT
    AAGGAAGCACATGATTTACAAGAAGCCAATACGAAACAAACAAGTATTCAAAAGTTTGAA
    AAATCTCTAGTTTTAGCAATTGGCTATGCAGGTACGATTGGTGGCTTGGGTACATTAATC
    GGAACCCCGCCATTAATTATTTTAAAAGGACAATACATGCAACATTTTGGACATGAAATT
    AGTTTTGCTAAATGGATGATTGTAGGGATTCCAACGGTCATTGTTTTGTTAGGTATTACT
    TGGCTCTATTTAAGATATGTTGCGTTTAGACATGATTTGAAATATTTACCTGGTGGTCAG
    ACGTTAATTAAACAAAAGTTAGACGAGCTTGGCAAAATGAAGTATGAAGAAAAGGTAGTA
    CAAACTATCTTTGTACTTGCCAGCTTATTATGGATTACAAGAGAGTTTCTTCTGAAAAAA
    TGGGAAGTTACGTCATCTGTTGCAGATGGTACGATTGCTATTTTTATATCAATATTATTA
    TTTATTATTCCAGCTAAAAATACTGAAAAACATCGCCGTATCATTGACTGGGAAGTTGCA
    AAAGAGCTCCCTTGGGGTGTATTAATTTTATTTGGTGGCGGTTTAGCATTAGCGAAAGGT
    ATTTCTGAAAGTGGTTTAGCAAAATGTTTAGGCGAACAGTTGAAATCATTAAATGGTGTT
    AGTCCGATTCTTATTGTAATTGTCATAACAATCTTTGTCTTATTTTTAACTGAAGTGACA
    TCTAATACTGCAACTGCAACGATGATTTTACCGATTTTAGCAACGTTGTCTGTTGCTGTT
    GGAGTACATCCATTACTACTTATGGCACCTGCAGCTATGGCGGCTAACTGTGCATACATG
    TTACCAGTAGGGACACCACCGAATGCAATTATCTTTGGTTCAGGTAAAATATCTATCAAA
    CAAATGGCATCAGTAGGATTCTGGGTAAACTTAATCAGTGCAATAATTATTATTTTAGTC
    GTGTATTATGTAATGCCTATAGTTTTAGGTATTGATATAAATCAACCACTGCCATTGAAA
    TAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1563

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001950
  • symbol: JSNZ_001950
  • description: SLC13 family permease
  • length: 520
  • theoretical pI: 9.94127
  • theoretical MW: 57102.4
  • GRAVY: 0.7725

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds transporter, divalent anion:Na+ symporter (DASS) family (TIGR00785; HMM-score: 289.2)
    Metabolism Transport and binding proteins Anions transporter, divalent anion:Na+ symporter (DASS) family (TIGR00785; HMM-score: 289.2)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    IT (CL0182) Na_sulph_symp; Sodium:sulfate symporter transmembrane region (PF00939; HMM-score: 276.8)
    CitMHS; Citrate transporter (PF03600; HMM-score: 236.4)
    and 2 more
    DctM; Tripartite ATP-independent periplasmic transporter, DctM component (PF06808; HMM-score: 15.8)
    no clan defined DUF6234; Family of unknown function (DUF6234) (PF19747; HMM-score: 8.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002163
    • TAT(Tat/SPI): 0.000336
    • LIPO(Sec/SPII): 0.020447
  • predicted transmembrane helices (TMHMM): 14

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEANTKQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKCLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Carbon catabolism;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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