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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_001678
- pan locus tag?: SAUPAN004317000
- symbol: JSNZ_001678
- pan gene symbol?: phoP
- synonym:
- product: winged helix-turn-helix domain-containing protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_001678
- symbol: JSNZ_001678
- product: winged helix-turn-helix domain-containing protein
- replicon: chromosome
- strand: -
- coordinates: 1714828..1715532
- length: 705
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGTCGCAAAAAGTGTTGGTAGTAGATGACGAACATTCAATCGTAACATTACTTAAATAT
AACTTAGAAACAGCTGGTTATGAAGTTGTTGTCGCATTTGATGGTGATGAGGCTTTAGAA
AAGGTAGAAAGTGAACAGTCAGATTTAATTATTTTAGATGTTATGCTACCTAAAAAAGAT
GGCATTGACGTATGTAAGACTGTAAGAACAAATAAAAATTTAGTCCCTATATTAATGTTA
ACGGCGAAAAATGATGAGTTTGATCGGGTATTAGGTTTAGAATTAGGTGCCGATGACTAT
ATGACTAAGCCTTTTTCACCTAGAGAAGTTGTTGCCCGTGTGAAAGCCATTTTAAGACGT
TCTCAATTTGTAAAAGAAGTAGAAGAGATTGATGATGATATTACCATCGGATCGATACGT
ATTAGACCCGATTATTTTGAAGTATATAAGCATAATGAGTTATTGGAGCTAACACCGAAA
GAATTTGAACTCTTGCTTTATTTGATAGAAAGACAAGGCAGAGTCATTACGAGAGAGCAT
ATGTTAAATACGGTATGGAATTATGAATTTGCAGGAGACTCAAGAATTGTTGATGTACAT
ATCAGTCATTTAAGAGATAAATTAGAAGATAATCCTAAGAAGCCACAACTTATTAAAACT
GTGCGTGGCTTAGGCTATAAATTGGAAAGACCTAAAGAACAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_001678
- symbol: JSNZ_001678
- description: winged helix-turn-helix domain-containing protein
- length: 234
- theoretical pI: 4.90242
- theoretical MW: 27112
- GRAVY: -0.34188
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions phosphate regulon transcriptional regulatory protein PhoB (TIGR02154; HMM-score: 237.2)Signal transduction Two-component systems phosphate regulon transcriptional regulatory protein PhoB (TIGR02154; HMM-score: 237.2)Regulatory functions DNA interactions heavy metal response regulator (TIGR01387; HMM-score: 191.6)and 7 moreproteobacterial dedicated sortase system response regulator (TIGR03787; HMM-score: 134.9)Central intermediary metabolism Nitrogen metabolism nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 74.5)Regulatory functions DNA interactions nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 74.5)Signal transduction Two-component systems nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 74.5)Cellular processes Sporulation and germination sporulation transcription factor Spo0A (TIGR02875; HMM-score: 60.2)Regulatory functions DNA interactions PEP-CTERM-box response regulator transcription factor (TIGR02915; HMM-score: 40.4)Signal transduction Two-component systems TMAO reductase sytem sensor TorS (TIGR02956; EC 2.7.13.3; HMM-score: 39.2)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: HTH (CL0123) Trans_reg_C; Transcriptional regulatory protein, C terminal (PF00486; HMM-score: 107.8)CheY (CL0304) Response_reg; Response regulator receiver domain (PF00072; HMM-score: 106.9)and 5 morePDE8A_N; PDE8A-like, N-terminal domain (PF23198; HMM-score: 22.8)GlnR_1st; Transcription regulator GlnR, N-terminal domain (PF21695; HMM-score: 18)NADP_Rossmann (CL0063) TrkA_N; TrkA-N domain (PF02254; HMM-score: 13.5)CheY (CL0304) FleQ; Flagellar regulatory protein FleQ (PF06490; HMM-score: 13.2)NADP_Rossmann (CL0063) Cons_hypoth95; Conserved hypothetical protein 95 (PF03602; HMM-score: 11.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9795
- Cytoplasmic Membrane Score: 0.0159
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0045
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001926
- TAT(Tat/SPI): 0.000095
- LIPO(Sec/SPII): 0.000223
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MSQKVLVVDDEHSIVTLLKYNLETAGYEVVVAFDGDEALEKVESEQSDLIILDVMLPKKDGIDVCKTVRTNKNLVPILMLTAKNDEFDRVLGLELGADDYMTKPFSPREVVARVKAILRRSQFVKEVEEIDDDITIGSIRIRPDYFEVYKHNELLELTPKEFELLLYLIERQGRVITREHMLNTVWNYEFAGDSRIVDVHISHLRDKLEDNPKKPQLIKTVRGLGYKLERPKEQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : pnpS < JSNZ_001678
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p)