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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001337
  • pan locus tag?: SAUPAN003740000
  • symbol: plsY
  • pan gene symbol?: plsY
  • synonym:
  • product: glycerol-3-phosphate 1-O-acyltransferase PlsY

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001337
  • symbol: plsY
  • product: glycerol-3-phosphate 1-O-acyltransferase PlsY
  • replicon: chromosome
  • strand: -
  • coordinates: 1347199..1347807
  • length: 609
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGATGATAATCGTCATGTTACTACTAAGTTATCTTATCGGCGCTTTCCCAAGTGGATTC
    GTAATTGGAAAATTATTTTTCAAAAAAGATATTAGACAATTTGGTAGTGGTAATACTGGC
    GCTACTAATAGCTTTAGAGTATTAGGTCGTCCTGCAGGATTCTTGGTAACATTTCTAGAT
    ATTTTCAAAGGGTTCATAACTGTTTTCTTCCCTTTATGGTTACCAGTTCACGCAGATGGC
    CCTATTAGTACTTTTTTTACAAATGGTTTAATTGTTGGCTTATTCGCTATACTTGGACAC
    GTTTATCCTGTTTATTTAAAATTCCAAGGTGGCAAAGCTGTTGCAACTAGTGCAGGTGTC
    GTCTTGGGAGTCAATCCGATACTTTTACTAATACTTGCAATTATCTTCTTTATTGTATTG
    AAGATTTTTAAATATGTTTCTTTAGCAAGTATCGTTGCAGCAATTTGCTGTGTGATTGGC
    TCGCTTATCATTCAAGACTATATTTTATTAGTCGTTAGTTTCTTAGTTTCAATCATATTG
    ATAATTAGACATCGCTCTAATATCGCAAGGATTTTTAGAGGCGAAGAACCTAAAATAAAA
    TGGATGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    609

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001337
  • symbol: PlsY
  • description: glycerol-3-phosphate 1-O-acyltransferase PlsY
  • length: 202
  • theoretical pI: 10.6347
  • theoretical MW: 22231.9
  • GRAVY: 1.16733

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.1.15?  ExPASy
    Glycerol-3-phosphate 1-O-acyltransferase Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate
  • TIGRFAM:
    Metabolism Fatty acid and phospholipid metabolism Biosynthesis acyl-phosphate glycerol 3-phosphate acyltransferase (TIGR00023; EC 2.3.1.-; HMM-score: 199.7)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined G3P_acyltransf; Glycerol-3-phosphate acyltransferase (PF02660; HMM-score: 181.3)
    and 1 more
    Ribophorin_II_C; Ribophorin_II, C-terminal domain (PF25147; HMM-score: 8.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.047773
    • TAT(Tat/SPI): 0.000894
    • LIPO(Sec/SPII): 0.040964
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MMIIVMLLLSYLIGAFPSGFVIGKLFFKKDIRQFGSGNTGATNSFRVLGRPAGFLVTFLDIFKGFITVFFPLWLPVHADGPISTFFTNGLIVGLFAILGHVYPVYLKFQGGKAVATSAGVVLGVNPILLLILAIIFFIVLKIFKYVSLASIVAAICCVIGSLIIQDYILLVVSFLVSIILIIRHRSNIARIFRGEEPKIKWM

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: LexA (repression) regulon
    LexA(TF)important in SOS response;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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