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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000987
  • pan locus tag?: SAUPAN003212000
  • symbol: JSNZ_000987
  • pan gene symbol?:
  • synonym:
  • product: IDEAL domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000987
  • symbol: JSNZ_000987
  • product: IDEAL domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 995444..995662
  • length: 219
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGAAATACAATACTAATGTTAAACATACAACTTTAGAAGCGTTTGTCACAACTGTCAAT
    GATTTGGGTATTGAATTAATTATCAATGAAGCACTTCGAGAGGTAAGAAAACGACAGCTC
    ATAGAACTTATAGATGACGCACTCGTCAATAAAGATGAAGCAGCATTTAATCAATATACG
    GCAGAATACAAAAATTTGGAGGCATTTCTCGGTGAATAA
    60
    120
    180
    219

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_000987
  • symbol: JSNZ_000987
  • description: IDEAL domain-containing protein
  • length: 72
  • theoretical pI: 4.41444
  • theoretical MW: 8302.34
  • GRAVY: -0.298611

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined IDEAL; IDEAL domain (PF08858; HMM-score: 50.6)
    and 3 more
    Ac76; Orf76 (Ac76) (PF05814; HMM-score: 13.3)
    DarP; Dual-action ribosomal maturation protein DarP (PF04751; HMM-score: 13.2)
    DUF4903; Domain of unknown function (DUF4903) (PF16246; HMM-score: 13.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9306
    • Cytoplasmic Membrane Score: 0.0274
    • Cell wall & surface Score: 0.0032
    • Extracellular Score: 0.0388
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003559
    • TAT(Tat/SPI): 0.000123
    • LIPO(Sec/SPII): 0.000257
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MKYNTNVKHTTLEAFVTTVNDLGIELIINEALREVRKRQLIELIDDALVNKDEAAFNQYTAEYKNLEAFLGE

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism;  regulation predicted or transferred from N315 and NCTC 8325  [1]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]