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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000807
  • pan locus tag?: SAUPAN001455000
  • symbol: JSNZ_000807
  • pan gene symbol?: —
  • synonym:
  • product: type II toxin-antitoxin system PemK/MazF family toxin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000807
  • symbol: JSNZ_000807
  • product: type II toxin-antitoxin system PemK/MazF family toxin
  • replicon: chromosome
  • strand: -
  • coordinates: 837924..838628
  • length: 705
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGAAAGAAATTCCACCAAAAAAAGTAGCAAAGATAAAATATTAAAAGCTGTAAATAAC
    TTTGAAGAGGTTTGCAATAGCGGAAAATTCAAATTTAAATATTTGGATGACTGGCTTTTT
    ACAAAATCAATAATTTTTAAAAATGAAACAACCTTAACTAACCAAAAAAACTTTAAAGTG
    TATCCAAGAGGTACTATTGTATACGCTAAACTTGGTGTTAACATTGGTTCTGAATTCTCA
    GGGAATCATTTTTGCGTCGTTTTAAATAAAAATGACAACAAACGCAATGAGCTAATTACT
    ATAGTTCCACTTACTTCAAAAGACACCAAATTTTCTTTAAAATTACAAGAGAATTTAATA
    CTAAAAGCTTTAGAAAAAATGAAAACTGACCACAAAACTTTACGATTCGATTTGGATAGA
    ATAAAAGAAATGCACGCAAGATCCACAAAAGTAAAAAACTTAAATTCAGCAATCGAAAAA
    GAACTTGATGAGATTGAAAATAATTATATGCAACTCGCAAAAATAATTGAGCGTTACGAA
    AGGTTTGTAGGCAAACAAACTTATGCAATTCCATCTCAAGTTATCACTATCAGTAAAAAA
    AGAATAAGCACACTTAATGATTACGATCCAACTGGCCATATATCTTTCAATGAAGAAACT
    TTAAAAATTATAGAAGATTTTATGAAAGCTAACATTTTATCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    705

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000807
  • symbol: JSNZ_000807
  • description: type II toxin-antitoxin system PemK/MazF family toxin
  • length: 234
  • theoretical pI: 10.0448
  • theoretical MW: 27231.3
  • GRAVY: -0.564957

⊟Function[edit | edit source]

  • TIGRFAM:
    SH3 domain protein (TIGR04211; HMM-score: 13.5)
    flagellar motor stator protein MotA (TIGR03818; HMM-score: 12.6)
    type VI secretion-associated protein, ImpA family (TIGR03363; HMM-score: 12.5)
  • TheSEED:
  • PFAM:
    SH3 (CL0010) PemK_toxin; PemK-like, MazF-like toxin of type II toxin-antitoxin system (PF02452; HMM-score: 37.9)
    and 6 more
    no clan defined Nsp1_C; Nsp1-like C-terminal region (PF05064; HMM-score: 23.2)
    SH3 (CL0010) MTR4_beta-barrel; Mtr4-like, beta-barrel domain (PF13234; HMM-score: 16.7)
    no clan defined Fzo_mitofusin; fzo-like conserved region (PF04799; HMM-score: 14.7)
    Enkurin; Calmodulin-binding (PF13864; HMM-score: 14.6)
    Ferritin (CL0044) DUF892; Domain of unknown function (DUF892) (PF05974; HMM-score: 13.7)
    no clan defined HEF_HK; HEF_HK domain (PF19191; HMM-score: 12.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.6402
    • Cytoplasmic Membrane Score: 0.0988
    • Cell wall & surface Score: 0.0142
    • Extracellular Score: 0.2469
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011301
    • TAT(Tat/SPI): 0.00065
    • LIPO(Sec/SPII): 0.00178
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MERNSTKKSSKDKILKAVNNFEEVCNSGKFKFKYLDDWLFTKSIIFKNETTLTNQKNFKVYPRGTIVYAKLGVNIGSEFSGNHFCVVLNKNDNKRNELITIVPLTSKDTKFSLKLQENLILKALEKMKTDHKTLRFDLDRIKEMHARSTKVKNLNSAIEKELDEIENNYMQLAKIIERYERFVGKQTYAIPSQVITISKKRISTLNDYDPTGHISFNEETLKIIEDFMKANILS

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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