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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000705
  • pan locus tag?: SAUPAN002638000
  • symbol: JSNZ_000705
  • pan gene symbol?: sstB
  • synonym:
  • product: iron chelate uptake ABC transporter family permease subunit

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000705
  • symbol: JSNZ_000705
  • product: iron chelate uptake ABC transporter family permease subunit
  • replicon: chromosome
  • strand: +
  • coordinates: 740290..741246
  • length: 957
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCGCAACAATAATAAAAAAATAATGCTTTTAATTGCAGTAACGTTATTAATTAGTATG
    CTGTACTTATTTGTAGGTATTGATTTTGAAATATTTGAATATCAATTTTCAAGTCGTTTA
    AGAAAGTTCATATTAATTATTTTAGTAGGTGCTGCCATTGCAACTTCAGTGGTGATTTTT
    CAAGCGATTACAAATAACCGTCTATTGACACCATCAATAATGGGGTTAGATGCAGTTTAT
    TTATTTATCAAAGTATTGCCAGTCTTTTTATTTGGAATTCAATCGGTATGGGTTACTAAT
    GTATATTTGAACTTTATATTAACACTTATAACGATGGTGTTATTCGCACTAATCCTATTC
    CAAGGTATCTTTAAAATCGGACATTTTTCAATTTATTTTATCTTACTTATTGGTGTCCTT
    TTAGGAACATTTTTTAGAAGCATAACAGGTTTTATTCAACTGATTATGGATCCTGAGTCA
    TTTTTAGCAATACAAAGTAGTATGTTTGCTAATTTTAATGCTTCTAATTCGAATTTAGTT
    ACTTTCTCAGCAGTGCTATTAGTAATCTTATTAGTCATTACAATTTTACTATTGCCTTAT
    TTAGATGTATTGCTTTTAGGTCGTGCTGAAGCAATTAATCTGGGGATATCGTATGAAAAA
    TTAACGCGAATTCTACTTGTAATAGTCTCAGTTTTAGTTTCTGTGTCAACTGCATTAGTA
    GGACCAATTACATTTTTAGGTTTATTAACTGTAAATCTAGCGCATGAACTAATGAAGACG
    TATGAACATAAGTATATTTTAATTGCGACAATTTGCTTGAGTTGGATTAGTTTATTTAGT
    GCGCAATGGGTAGTTGAAAATGTGTTTGAAGCTACGACAGAAATGAGTATACTTATTGAT
    TTGATTGGTGGAAGTTATTTCATTTATCTATTAGTTAGAAGGAGAAATGCGCAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    957

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_000705
  • symbol: JSNZ_000705
  • description: iron chelate uptake ABC transporter family permease subunit
  • length: 318
  • theoretical pI: 9.18406
  • theoretical MW: 35777
  • GRAVY: 1.17138

Function[edit | edit source]

  • TIGRFAM:
    proposed F420-0 ABC transporter, permease protein (TIGR03869; HMM-score: 45.3)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Membrane_trans (CL0142) FecCD; FecCD transport family (PF01032; HMM-score: 171.2)
    and 1 more
    no clan defined TMEM141; TMEM141 protein family (PF15110; HMM-score: 14)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 1
    • Cell wall & surface Score: 0
    • Extracellular Score: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008382
    • TAT(Tat/SPI): 0.001361
    • LIPO(Sec/SPII): 0.005901
  • predicted transmembrane helices (TMHMM): 9

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFILIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVYLNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPESFLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISYEKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWISLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator: Fur* (repression) regulon
    Fur*(TF)important in Iron homeostasis;  regulation predicted or transferred from N315 and NCTC 8325  [2]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]