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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000648
  • pan locus tag?: SAUPAN002564000
  • symbol: JSNZ_000648
  • pan gene symbol?:
  • synonym:
  • product: TIGR00730 family Rossman fold protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000648
  • symbol: JSNZ_000648
  • product: TIGR00730 family Rossman fold protein
  • replicon: chromosome
  • strand: -
  • coordinates: 681545..682111
  • length: 567
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGAAACGAATCGCAGTTTATTGTGGTGCAAGCAAAGGTCATGACCCTTCATATGTACAA
    AAAGCATACGATTTAGGTAACTATTTTGCTGAACAAGGTTATGAATTAGTATTTGGTGCA
    GGGTCAATTGGTATTATGGGTGCCATTCAAGATGGTGTATTAGATCATGGCGGCAAAGCT
    ATTGGCGTCATGCCTAAAATGTTAGATGAACATGAAATCACAAGCCAACGTTTAACTGAA
    TTAATTTTAGTTGATTCTATGCATGAACGTAAAAATAAAATGGCAGAACTTGCAGATGCA
    TTTGTCATGGCTCCTGGTGGCGCAGGTTCACTAGAAGAATTTTTCGAAATGTATAGTTGG
    GCTCAAATAGGTATCCATGAAAAGCCTATTGCCATTTATAATATTAATGGCTTTTTCAAT
    CCACTACAAACAATGATTGACCATATGATTGAGGAAGGTTTTATTGATCCTAAGTATCGT
    GCTCTTGCACCGTTATGCGACACTAAGGAATCATTAATAGAATCAATATTAAATTTCAAA
    CCTCTGGGTACTCGTTCATACGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    567

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_000648
  • symbol: JSNZ_000648
  • description: TIGR00730 family Rossman fold protein
  • length: 188
  • theoretical pI: 4.75801
  • theoretical MW: 20874.8
  • GRAVY: -0.112766

Function[edit | edit source]

  • TIGRFAM:
    Hypothetical proteins Conserved TIGR00730 family protein (TIGR00730; HMM-score: 197.3)
    and 3 more
    Hypothetical proteins Conserved TIGR00725 family protein (TIGR00725; HMM-score: 36.3)
    Cellular processes Cellular processes DNA transformation DNA protecting protein DprA (TIGR00732; HMM-score: 12.3)
    gliding motility-associated lipoprotein GldK (TIGR03525; HMM-score: 10.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    SLOG (CL0349) Lysine_decarbox; Possible lysine decarboxylase (PF03641; HMM-score: 165.3)
    and 1 more
    LDcluster4; SLOG cluster4 family (PF18306; HMM-score: 57.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9918
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0079
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017622
    • TAT(Tat/SPI): 0.000218
    • LIPO(Sec/SPII): 0.000939
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MKRIAVYCGASKGHDPSYVQKAYDLGNYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: SigB (activation) regulon
    SigB(sigma factor)controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026)   other strains

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here.

Literature[edit | edit source]

References[edit | edit source]

  1. Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

Relevant publications[edit | edit source]