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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000494
  • pan locus tag?: SAUPAN002305000
  • symbol: nusG
  • pan gene symbol?: nusG
  • synonym:
  • product: transcription termination/antitermination protein NusG

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000494
  • symbol: nusG
  • product: transcription termination/antitermination protein NusG
  • replicon: chromosome
  • strand: +
  • coordinates: 523411..523959
  • length: 549
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTCTGAAGAAGTTGGCGCAAAGCGTTGGTATGCAGTGCATACATATTCTGGATATGAA
    AATAAAGTTAAAAAGAATTTAGAAAAAAGAGTAGAATCTATGAATATGACTGAACAAATC
    TTTAGAGTAGTCATACCGGAAGAAGAAGAAACTCAAGTAAAAGATGGCAAAGCTAAAACG
    ACTGTTAAAAAAACATTCCCTGGATATGTTTTAGTGGAATTAATCATGACAGATGAATCA
    TGGTATGTGGTAAGAAATACACCAGGCGTTACTGGTTTTGTAGGTTCTGCAGGTGCAGGG
    TCTAAGCCAAATCCATTGTTACCAGAAGAAGTTCGCTTCATCTTAAAACAAATGGGTCTT
    AAAGAAAAGACTATCGATGTTGAACTCGAAGTTGGCGAGCAAGTTCGTATTAAATCAGGT
    CCATTTGCGAATCAAGTTGGTGAAATTCAAGAAATTGAAACAGATAAGTTTAAGCTAACA
    GTATTAGTAGATATGTTTGGCCGAGAAACACCAGTAGAAGTTGAATTCGATCAAATAGAA
    AAGCTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    549

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000494
  • symbol: NusG
  • description: transcription termination/antitermination protein NusG
  • length: 182
  • theoretical pI: 4.78638
  • theoretical MW: 20677.6
  • GRAVY: -0.421978

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Transcription Transcription factors transcription termination/antitermination factor NusG (TIGR00922; HMM-score: 203.2)
    and 3 more
    NusG family protein (TIGR01956; HMM-score: 108.3)
    Genetic information processing Transcription Transcription factors transcription elongation factor/antiterminator RfaH (TIGR01955; HMM-score: 61.6)
    transcription elongation factor Spt5 (TIGR00405; HMM-score: 25.7)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NusG-like (CL0439) NusG; Transcription termination factor nusG (PF02357; HMM-score: 103.5)
    and 5 more
    SH3 (CL0010) KOW; KOW motif (PF00467; HMM-score: 30.5)
    DUF150_C; RimP C-terminal SH3 domain (PF17384; HMM-score: 16.2)
    SH3_KIN17_C; KIN17 C-terminal SH3 domain (PF25092; HMM-score: 15)
    no clan defined DUF3912; Protein of unknown function (DUF3912) (PF13051; HMM-score: 14.2)
    SH3 (CL0010) KOW5_SPT5; Transcription elongation factor SPT5, fifth KOW domain (PF23290; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9855
    • Cytoplasmic Membrane Score: 0.0012
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0132
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005909
    • TAT(Tat/SPI): 0.000544
    • LIPO(Sec/SPII): 0.00119
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEIQEIETDKFKLTVLVDMFGRETPVEVEFDQIEKL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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