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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000300
  • pan locus tag?: SAUPAN001888000
  • symbol: tatC
  • pan gene symbol?: tatC
  • synonym:
  • product: twin-arginine translocase subunit TatC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000300
  • symbol: tatC
  • product: twin-arginine translocase subunit TatC
  • replicon: chromosome
  • strand: -
  • coordinates: 337818..338480
  • length: 663
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATACTATTGTCGTTCGTCGTCACAGTCATCGTCGTATATGTTTCATCATTTTGGTGGATG
    ACACCATTCATAACGTATATTACCCGTGCACATGTGTCCTTACATGCATTTTCATTCACA
    GAAATGATCCAAATATACGTGATGATTATATTTTTCATCGCGTTTTGTTTCATTTCACCA
    GTCATGTTTTATCAATTGTGGGCATTCATTGCACCTGGATTACATAATAATGAACGTCAA
    TTTATTTATAAATATAGTTTTTTCAGCGTGTTATTATTCTGTGCTGGCGTCGCTTTTGCA
    TTTTATGTTGGCTTTCCAATAATCATTCAATTCGCGTTAAAATTATCATTAACTTTAAAC
    ATTTCGCCTGTCATTGGCTTTAAAGCATATTTGATTGAACTCATACGTTGGTTATTCACA
    TTTGGTCTTCTATTTCAATTACCAATATTATTTATGGGTCTTGCAAAATTCGGTCTTATA
    GATACCACATCATTGAAACATTATCGTAAATATATTTATTTTGCTTGCTTTGTGCTGGCG
    AGTATAATTGCACCACCAGACATAACATTAAATATATTACTCACATTGCCACTCATATTG
    CTCTTTGAGTTCAGTATGTTCATTGTTAAGTTCACATGCCGAGGCAAACCGCCAACACAT
    TGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    663

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000300
  • symbol: TatC
  • description: twin-arginine translocase subunit TatC
  • length: 220
  • theoretical pI: 9.48042
  • theoretical MW: 25576.8
  • GRAVY: 1.13455

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking twin arginine-targeting protein translocase TatC (TIGR00945; HMM-score: 149.5)
    Sec-independent protein translocase TatC (TIGR01912; HMM-score: 120.1)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined TatC; Sec-independent protein translocase protein (TatC) (PF00902; HMM-score: 146.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 7
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9989
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0009
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00329
    • TAT(Tat/SPI): 0.000325
    • LIPO(Sec/SPII): 0.064301
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLLSFVVTVIVVYVSSFWWMTPFITYITRAHVSLHAFSFTEMIQIYVMIIFFIAFCFISPVMFYQLWAFIAPGLHNNERQFIYKYSFFSVLLFCAGVAFAFYVGFPIIIQFALKLSLTLNISPVIGFKAYLIELIRWLFTFGLLFQLPILFMGLAKFGLIDTTSLKHYRKYIYFACFVLASIIAPPDITLNILLTLPLILLFEFSMFIVKFTCRGKPPTH

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: Fur* (repression) regulon
    Fur*(TF)important in Iron homeostasis;  regulation predicted or transferred from N315 and NCTC 8325  [2]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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