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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000261
  • pan locus tag?: SAUPAN001230000
  • symbol: JSNZ_000261
  • pan gene symbol?: —
  • synonym:
  • product: FtsX-like permease family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000261
  • symbol: JSNZ_000261
  • product: FtsX-like permease family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 296404..297453
  • length: 1050
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGTTTTTAGCTTGGAATGAAATACGGCGCAACAAATTGAAGTTTGGACTGATTATTGGT
    GTGTTGGCAATGATAAGTTACTTACTTTTTCTATTGTCGGGATTGGCTAATGGTTTAATT
    AATATGAATAAAGAAGGTATTGATAAGTGGCATGCGAATGCCATTGTGTTAAATAAGGAT
    GCTAATCAAACTGTGCAACAATCTGTTTTTAACAAGAAAGATATTGAAAATAAATACAAG
    AAGCAAGCTACTTTGAAGCAAACAGGGGAAATTGTGTCTAATGGCCATCAAAAAGACAAT
    GTTTTAGTGTTCGGTGTTGAAAAGTCATCATTTTTAGTTCCGAGTTTAATAGAAGGGCAT
    AAAGCGACTAAAGATAATGAAGTGTTAGCTGATGAAACGCTTAAAAATAAAGGATTTAAA
    ATTGGTGACACATTATCACTATCTCAATCAGATGAAAAATTGCATATCGTAGGTTTTACA
    GAAAGTGCAAAATATAATGCGTCACCAGTCATTTTCACGAATGACGCTACCATTGCCAAA
    ATCAATCCTAGATTGACTGGAGATAAAATTAATGCAGTTGTTGTACGTGATACAAATTGG
    AAAGACAAAAAATTAAACCAAGAGCTTGAAGCGGTAAGTATTAATGACTTTATTGAAAAT
    TTACCAGGTTATAAACCACAGAACTTAACATTAAACTTTATGATTTCATTCTTATTTGTC
    ATTTCAGCTACAGTTATAGGTATATTCTTATATGTCATGACATTACAAAAAACAAGTTTA
    TTTGGCATATTAAAGGCTCAAGGATTTACGAATGGCTATTTAGCGAACGTAGTTATTTCG
    CAGACGCTCATATTAGCATTATTTGGTACGGCATTTGGCTTACTGTTAACAGGCGTTACA
    GGTGCATTTTTACCTGATGCAGTACCTGTCAAATTCGATGTACTAACATTGCTCGTATTT
    GCAATTGTGTTAATGATTGTCTCTGTATTAGGAAGTTTATTCTCCATTTTAACAATTAGA
    AAAATAGATCCGTTAAAGGCGATTGGGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1050

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000261
  • symbol: JSNZ_000261
  • description: FtsX-like permease family protein
  • length: 349
  • theoretical pI: 9.92337
  • theoretical MW: 38426.8
  • GRAVY: 0.289685

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other ABC exporter transmembrane subunit, DevC protein (TIGR01185; HMM-score: 27.3)
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 24.5)
    and 2 more
    Metabolism Energy metabolism Photosynthesis 2-vinyl bacteriochlorophyllide hydratase (TIGR02020; EC 4.2.1.-; HMM-score: 10.7)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 9.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease C-terminal (PF02687; HMM-score: 40.9)
    and 1 more
    ABC-2 (CL0181) PDR_CDR; CDR ABC transporter (PF06422; HMM-score: 11.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.289997
    • TAT(Tat/SPI): 0.008746
    • LIPO(Sec/SPII): 0.06477
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFLAWNEIRRNKLKFGLIIGVLAMISYLLFLLSGLANGLINMNKEGIDKWHANAIVLNKDANQTVQQSVFNKKDIENKYKKQATLKQTGEIVSNGHQKDNVLVFGVEKSSFLVPSLIEGHKATKDNEVLADETLKNKGFKIGDTLSLSQSDEKLHIVGFTESAKYNASPVIFTNDATIAKINPRLTGDKINAVVVRDTNWKDKKLNQELEAVSINDFIENLPGYKPQNLTLNFMISFLFVISATVIGIFLYVMTLQKTSLFGILKAQGFTNGYLANVVISQTLILALFGTAFGLLLTGVTGAFLPDAVPVKFDVLTLLVFAIVLMIVSVLGSLFSILTIRKIDPLKAIG

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: SigB (activation) regulon
    SigB(sigma factor)controlling a large regulon involved in stress/starvation response and adaptation; transcription unit predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026)   other strains

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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