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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000259
  • pan locus tag?: SAUPAN001224000
  • symbol: brnQ
  • pan gene symbol?: brnQ2
  • synonym:
  • product: branched-chain amino acid transport system II carrier protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000259
  • symbol: brnQ
  • product: branched-chain amino acid transport system II carrier protein
  • replicon: chromosome
  • strand: -
  • coordinates: 293374..294681
  • length: 1308
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    TTGAAAAAACAAGTTATTATTTCGGGCCTCATGTTATTTTCACTATTTTTTGGAGCCGGA
    AATTTAATATTCCCGCCCATGCTTGGCCATACAGCGGGTCAAAATATGTGGATTGGTATG
    CTAGGCTTTGCCCTTACAGGCATATTACTCCCCTTTATTACTGTTATTGTTGTTGCATTT
    TATGATGAAGGTGTTGAAAGTGTAGGCAATCGTATACATCCATGGTTCGGGTTTATTTTT
    GCTGTCGTGATTTACATGTCTATCGGAGCATTTTACGGTATTCCACGTGCTGCAAATGTC
    GCGTACGAAATTGGTACAAGACACATTTTACCTGTGCACAACCAATGGACTTTAATTATA
    TTCGCAGCAATCTTTTTTGCCATCGTTTACTGGATTAGTTTAAATCCATCGAAAATCGTT
    GATAATTTAGGTAAATTATTAACACCGTTATTACTATTAATGGTCGCTCTATTAAGTATT
    GCTGTCATTTTCAACCCTGAATCTGCACTAAGTGCACCTAAGGATAAATATATAACACAT
    CCTTTCATTTCAGGAAGTTTGGAAGGCTATTTTACAATGGATCTTGTTGCTGCGTTAGCT
    TTTTCCGTTGTCATTGTCAATGGCTATAAGTTTAAAGGCCTCACAGATCGCATGAAAATT
    TTAAAATATGTCTGCTTTTCAGGTCTTATTGCAGCCATATTACTTGGAATGATTTACTTT
    GCACTTGCATACGTTGGGGCATCAACAGCTCCAGGAAACTTTAAAGATGGTACAGATATA
    TTGACGTACAACTCATTACGCGTATTTGGTTCGTTCGGTAACCTCGTATTTGGAATGACG
    GTTATTCTTGCATGCCTAACAACATGTATAGGACTCGTCAACGCTTGTGCAACATTTACT
    AAGAAACACGTACCTAAGTTTTCTTATAAAATATTTGCACTTATTTTCTCTATCATAGGG
    TTCTTATTTACAACACTTGGTTTAGAAATGATTTTAAAAATTGCTGTACCATTATTGACT
    TTAATTTATCCCGTGTCTATTGCACTTGTACTGATATCATTTGCTAACATGTTTAGCACA
    TTCAGATTCAGTTGGGCCTATCGACTCGCAACTGTTATTACATTGATTATTTCAATTTTA
    CAAATACTAAATAGTTTTAACTTATTACACGGTGTTATTTTGAAATCGTTTATGATGTTA
    CCTTTAGCAGATATCGATTTAGCTTGGCTTGTACCATTCATGCTCTTTGCTATTATCGGT
    TTCATAATCGATGTATTTATACGCCGTCCGAAACAAGCTACAACTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1308

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000259
  • symbol: BrnQ
  • description: branched-chain amino acid transport system II carrier protein
  • length: 435
  • theoretical pI: 9.76448
  • theoretical MW: 48018.6
  • GRAVY: 1.04391

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines branched-chain amino acid transport system II carrier protein (TIGR00796; HMM-score: 404.8)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    APC (CL0062) Branch_AA_trans; Branched-chain amino acid transport protein (PF05525; HMM-score: 446.1)
    and 1 more
    no clan defined Plant_vir_prot; Plant viral movement protein (PF01307; HMM-score: 18.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.083359
    • TAT(Tat/SPI): 0.00327
    • LIPO(Sec/SPII): 0.187431
  • predicted transmembrane helices (TMHMM): 12

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKQVIISGLMLFSLFFGAGNLIFPPMLGHTAGQNMWIGMLGFALTGILLPFITVIVVAFYDEGVESVGNRIHPWFGFIFAVVIYMSIGAFYGIPRAANVAYEIGTRHILPVHNQWTLIIFAAIFFAIVYWISLNPSKIVDNLGKLLTPLLLLMVALLSIAVIFNPESALSAPKDKYITHPFISGSLEGYFTMDLVAALAFSVVIVNGYKFKGLTDRMKILKYVCFSGLIAAILLGMIYFALAYVGASTAPGNFKDGTDILTYNSLRVFGSFGNLVFGMTVILACLTTCIGLVNACATFTKKHVPKFSYKIFALIFSIIGFLFTTLGLEMILKIAVPLLTLIYPVSIALVLISFANMFSTFRFSWAYRLATVITLIISILQILNSFNLLHGVILKSFMMLPLADIDLAWLVPFMLFAIIGFIIDVFIRRPKQATT

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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