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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000157
  • pan locus tag?: SAUPAN001073000
  • symbol: JSNZ_000157
  • pan gene symbol?: —
  • synonym:
  • product: isoprenylcysteine carboxyl methyltransferase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000157
  • symbol: JSNZ_000157
  • product: isoprenylcysteine carboxyl methyltransferase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 189200..189694
  • length: 495
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGATTCTATCTATATTACTTATCTTTTTCTGTATCAGACTTGTCAGCTTAAAGATATCT
    ATTAATCACTCAAAACAATTAAAAGCAGACGGTGCAGTTGAATATGGCGTTAAAAATTCG
    AAGTTTTTAGCAATAACACACGTTTTAATTTATGTATTGGCTGGTGTAGAGGCATTTATT
    AATAAAGATACATTTAGCTTTGCAAATGGTATTGGCTTAGTTATATTAATCTTTGCTTAT
    ATCATGTTATTTATGGTTATTAAAACTTTAGGTGGTATTTGGACATTAAAATTATTCATT
    TTACCTAACCATCCTATTATTAAATCTGGATTATATAAAATTACAAAACACCCAAATTAC
    TTCTTAAACATCATTCCTGAATTAATCGGTGTATTATTATTAACACACGCAACATATACA
    ACTATTTTATTAGTACCGTATGCGTATTTCTTATATGTACGTATTAAACAAGAAGAGAAA
    TTAATGAATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    495

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000157
  • symbol: JSNZ_000157
  • description: isoprenylcysteine carboxyl methyltransferase family protein
  • length: 164
  • theoretical pI: 10.0337
  • theoretical MW: 18648.6
  • GRAVY: 0.87378

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Steroid_dh (CL0115) ICMT; Isoprenylcysteine carboxyl methyltransferase (ICMT) family (PF04140; HMM-score: 104.7)
    and 3 more
    PEMT; Phospholipid methyltransferase (PF04191; HMM-score: 28.8)
    DUF1295; Protein of unknown function (DUF1295) (PF06966; HMM-score: 19.5)
    no clan defined DUF6773; Family of unknown function (DUF6773) (PF20563; HMM-score: 6.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9979
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.002
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.128804
    • TAT(Tat/SPI): 0.003604
    • LIPO(Sec/SPII): 0.017005
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MILSILLIFFCIRLVSLKISINHSKQLKADGAVEYGVKNSKFLAITHVLIYVLAGVEAFINKDTFSFANGIGLVILIFAYIMLFMVIKTLGGIWTLKLFILPNHPIIKSGLYKITKHPNYFLNIIPELIGVLLLTHATYTTILLVPYAYFLYVRIKQEEKLMNI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • data available for N315

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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