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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000149
  • pan locus tag?: SAUPAN001063000
  • symbol: JSNZ_000149
  • pan gene symbol?: —
  • synonym:
  • product: M23 family metallopeptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000149
  • symbol: JSNZ_000149
  • product: M23 family metallopeptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 180146..180724
  • length: 579
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGACAAAGCGACCAAAACGTATTTTGGCAACAATTATCATTTTTCTTTCACTATTATTT
    ACGATTATTTATATAGATGACATTCAAAAATGGTTTAACCAATATACCGATAAATTGACA
    CAAAATTATAAAGGACAAGGACACTCAAAATGGGAAGACTTTTTTAGAGGGAGTCGGATT
    ACTGAGACTTTTGGTAAATATCAACATTCACCATTTGATGGTAAGCATTATGGCGTTGAT
    TTTGCATTGCCAAAAGGTACACCAATTAAAGCGCCGACGAATGGTAAAGTAACACGTATC
    TTTAATAATGAATTAGGCGGCAAGGTATTACAGATTGCCGAAGACAATGGAGAATATCAC
    CAGTGGTATCTACACTTAGACAAATATAATGTCAAAGTAGGTGATCGAGTCAAAGCAGGT
    GATATTATTGCATATTCAGGCAATACAGGTAAACAAACGACAGGCGCACATTTACATTTT
    CAAAGAATGAAGGGTGGCGTAGGTAATGCATATGCAGAAGATCCAAAACCGTTTATCGAT
    CAGTTACCTGATGGGGAACGTAGCCTATATGATTTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    579

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000149
  • symbol: JSNZ_000149
  • description: M23 family metallopeptidase
  • length: 192
  • theoretical pI: 9.65057
  • theoretical MW: 21962.7
  • GRAVY: -0.621875

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.24.-?  ExPASy
  • TIGRFAM:
    ABC exporter membrane fusion protein, DevB family (TIGR02971; HMM-score: 10.2)
    Genetic information processing Transcription DNA-dependent RNA polymerase DNA-directed RNA polymerase, beta' subunit (TIGR02386; EC 2.7.7.6; HMM-score: 9.1)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Hybrid (CL0105) Peptidase_M23; Peptidase family M23 (PF01551; HMM-score: 95.6)
    and 6 more
    Biotin_lipoyl_2; Biotin-lipoyl like (PF13533; HMM-score: 20.7)
    Apocytochr_F_C; Apocytochrome F, C-terminal (PF01333; HMM-score: 17)
    Biotin_lipoyl; Biotin-requiring enzyme (PF00364; HMM-score: 15.8)
    RnfC_N; RnfC Barrel sandwich hybrid domain (PF13375; HMM-score: 14.3)
    no clan defined DUF2232; Predicted membrane protein (DUF2232) (PF09991; HMM-score: 12.3)
    HPIH; N-terminal domain with HPIH motif (PF13323; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0034
    • Cytoplasmic Membrane Score: 0.6058
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.3904
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.193253
    • TAT(Tat/SPI): 0.000752
    • LIPO(Sec/SPII): 0.012006
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNYKGQGHSKWEDFFRGSRITETFGKYQHSPFDGKHYGVDFALPKGTPIKAPTNGKVTRIFNNELGGKVLQIAEDNGEYHQWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHFQRMKGGVGNAYAEDPKPFIDQLPDGERSLYDL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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