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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_000142
- pan locus tag?: SAUPAN001056000
- symbol: JSNZ_000142
- pan gene symbol?: gisA
- synonym:
- product: ABC transporter ATP-binding protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_000142
- symbol: JSNZ_000142
- product: ABC transporter ATP-binding protein
- replicon: chromosome
- strand: -
- coordinates: 170019..171611
- length: 1593
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1561ATGTCAAATTTATTAGAAGTCAACAGTCTGAATGTACAATTCAATTATGATGAAACTACA
GTTCAAGCGGTAAAAAACGTCTCTTTCGAATTACGAAAAAAACATATCCTAGGTATTGTT
GGTGAATCAGGATCAGGAAAAAGTATTACTGCTAAATCTATTTTAGGGCTACTACCAGAT
TATCCAGATCACACATTAACAGGAGAAATTATTTTTAATGGGCAATCGTTAACTAATTTA
TCAACTTCAGCGTTACAACAAATTCGAGGCAAGGATATTTCAATGATTTTTCAAGATCCA
CTCTCTTCGTTGAATCCAAGATTAACGATTGGCAAACAAATTACAGAAGTACTATTTCAA
CATAAACGTGTATCTAAATCTGAAGCAAAGTCGATGACAATAGACATTTTAGAAAAAGTA
GGTATAAAACATGCAACTCGACAATTTGATGCTTATCCACATGAACTTTCTGGTGGTATG
CGTCAACGTGTCATGATAGCAATGGCATTGATTTTAAAGCCACAAATTTTAATCGCAGAT
GAACCAACAACGGCATTAGATGCCAGTACACAAAATCAATTACTGCAGTTAATGAAGTCC
CTTTATGAGTACACCGAAACGTCTATTATTTTTATCACTCACGATTTAGGCGCTGTGTAT
CAATTTTGCGACGATGTGATTGTAATGAAAGATGGAAGTGTCGTTGAAAGTGGCACGGTT
GAAAGTATTTTTAAATCGCCACAACATACCTATACGAAACGCTTAATAGATGCGATTCCT
GATATTCATCAAACGCGTCCGCCAAGACCGTTAAACAATGATATTTTATTAAAATTCGAT
CGCGTGAGCGTGGATTACAAGTCACCAAGTGGCAGCCTATACCGAGCAGTTAATGATATT
AACTTGGCTATTAGAAAGGGCGAAACATTAGGCATTGTCGGTGAATCAGGGTCAGGGAAA
TCGACATTAGCTAAGACGGTCGTCGGTCTAAAGGAAGTGTCAGAAGGCTTTATTTGGTAT
AATGAATTACCATTAAGTTTATTTAAAGATGATGAATTGAAATCTTTACGACAAGAGATA
CAAATGATTTTTCAAGATCCATTCGCATCTATTAACCCAAGATTTAAAGTCATTGATGTG
ATTAAACGACCACTAATCATTCATGGAAAAGTCAAAGATAATGATGACATTATTAAAACT
GTCGTATCGTTGTTAGAAAAAGTTGGCCTAGATCAAAGTTTCTTATATCGCTATCCACAC
GAATTATCTGGTGGGCAACGTCAGCGTGTAAGTATCGCGAGAGCACTTGCTGTAGAACCT
AAAGTGATTGTTTGCGACGAGGCAGTGTCCGCTTTAGACGTTTCAATTCAAAAAGATATC
ATCGAGTTATTAAAACAATTACAGTTAGACTTCGGCATCACTTATTTATTCATCACACAT
GACATGGGTGTTATCAATGAAATATGTGATCGCGTAGCAGTTATGAAAAATGGCGAAATC
GTTGAACTGAATAACACAGAAGATATTATCAAACATCCGCAATCAGACTATGCAAAGCAA
CTTATTTCAGAAGTAGCAGTTATTGCTAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_000142
- symbol: JSNZ_000142
- description: ABC transporter ATP-binding protein
- length: 530
- theoretical pI: 6.38931
- theoretical MW: 59175.9
- GRAVY: -0.0822641
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 445.7)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 413.8)and 79 moreD-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 335.5)Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 326.6)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 326.1)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 306.1)Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 290.2)Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 290.2)Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 279.9)Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 278.9)Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 278.4)ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 271.2)ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 266.8)Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 262.2)Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 259.4)Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 248)Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 234.3)Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 234.3)2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 233.4)Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 230.3)Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 225.1)Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 218.7)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 218.7)Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 216.8)Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 212.6)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 212.6)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 212.3)Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 212.3)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 212.3)Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 208.9)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 200.7)Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 200.7)Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 195)Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 195)Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 195)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 192.1)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 191.7)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 189.1)Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 189.1)Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 185.4)Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 185.4)Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 184)Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 183.4)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 182)Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 180.1)proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 178.6)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 177.5)Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 177.3)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 175.3)Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 169.6)Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 165.4)phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 163.6)thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 159.2)gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 154.3)Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 143.7)Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 143.7)lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 141.8)Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 136.3)Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 135.9)Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 133.9)Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 112.8)Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 112.8)Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 111)ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 96.2)Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 88.4)Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 88.4)Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 80.6)Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 74.7)Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 67.7)Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 65.3)DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 64)Transport and binding proteins Amino acids, peptides and amines oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain (TIGR01727; HMM-score: 42)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 19.2)P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 17.5)Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 15.1)Protein fate Degradation of proteins, peptides, and glycopeptides putative ATP-dependent protease (TIGR00764; HMM-score: 14.6)Unknown function General Mg chelatase-like protein (TIGR00368; HMM-score: 14.3)Protein fate Protein and peptide secretion and trafficking type VII secretion protein EssC (TIGR03928; HMM-score: 13)Central intermediary metabolism Nitrogen fixation Nif-specific regulatory protein (TIGR01817; HMM-score: 11.4)Regulatory functions DNA interactions Nif-specific regulatory protein (TIGR01817; HMM-score: 11.4)Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 8.7)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 222.5)and 49 moreSMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 53.8)AAA_22; AAA domain (PF13401; HMM-score: 41.9)no clan defined oligo_HPY; Oligopeptide/dipeptide transporter, C-terminal region (PF08352; HMM-score: 40.2)P-loop_NTPase (CL0023) AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 34.6)nSTAND3; Novel STAND NTPase 3 (PF20720; HMM-score: 29.2)AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 26.5)NB-ARC; NB-ARC domain (PF00931; HMM-score: 26)DUF87; Helicase HerA, central domain (PF01935; HMM-score: 25)Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 24.7)ABC_ATPase; P-loop domain (PF09818; HMM-score: 23.7)AAA_16; AAA ATPase domain (PF13191; HMM-score: 23)Sigma54_activat; Sigma-54 interaction domain (PF00158; HMM-score: 22.8)RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 22.7)nSTAND1; Novel STAND NTPase 1 (PF20703; HMM-score: 22.5)AAA_23; AAA domain (PF13476; HMM-score: 22)NPHP3_N; Nephrocystin 3, N-terminal (PF24883; HMM-score: 22)TniB; Bacterial TniB protein (PF05621; HMM-score: 21.3)NACHT; NACHT domain (PF05729; HMM-score: 20.3)AAA_33; AAA domain (PF13671; HMM-score: 19.2)AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 19)AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 18.8)AAA_19; AAA domain (PF13245; HMM-score: 17.6)DUF5906; Family of unknown function (DUF5906) (PF19263; HMM-score: 17.4)AAA_18; AAA domain (PF13238; HMM-score: 17.3)AAA_24; AAA domain (PF13479; HMM-score: 17.1)ATP-synt_ab; ATP synthase alpha/beta family, nucleotide-binding domain (PF00006; HMM-score: 16.8)RNA_helicase; RNA helicase (PF00910; HMM-score: 16.5)AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 16.3)ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 16)PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 15.8)Rad17; Rad17 P-loop domain (PF03215; HMM-score: 15.8)Sigma54_activ_2; Sigma-54 interaction domain (PF14532; HMM-score: 15.4)SbcC_Walker_B; SbcC/RAD50-like, Walker B motif (PF13558; HMM-score: 15)PhoH; PhoH-like protein (PF02562; HMM-score: 14.3)ATPase; KaiC (PF06745; HMM-score: 13.7)TsaE; Threonylcarbamoyl adenosine biosynthesis protein TsaE (PF02367; HMM-score: 13.4)FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 13.2)AIG1; AIG1 family (PF04548; HMM-score: 12.9)HTH (CL0123) DUF6262; Family of unknown function (DUF6262) (PF19776; HMM-score: 12.9)P-loop_NTPase (CL0023) MobB; Molybdopterin guanine dinucleotide synthesis protein B (PF03205; HMM-score: 12.6)MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 12.3)T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 12.1)G-alpha; G-protein alpha subunit (PF00503; HMM-score: 11.5)AAA_13; AAA domain (PF13166; HMM-score: 11.4)Cache (CL0165) dCache_2; Cache domain (PF08269; HMM-score: 11.3)no clan defined DUF3987; Protein of unknown function (DUF3987) (PF13148; HMM-score: 10.6)P-loop_NTPase (CL0023) SLFN-g3_helicase; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 9.9)AAA_10; AAA-like domain (PF12846; HMM-score: 9.9)AAA_15; AAA ATPase domain (PF13175; HMM-score: 9.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.04
- Cytoplasmic Membrane Score: 9.96
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 0
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.1194
- Cytoplasmic Membrane Score: 0.8621
- Cell wall & surface Score: 0.0007
- Extracellular Score: 0.0178
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006678
- TAT(Tat/SPI): 0.000447
- LIPO(Sec/SPII): 0.000277
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MSNLLEVNSLNVQFNYDETTVQAVKNVSFELRKKHILGIVGESGSGKSITAKSILGLLPDYPDHTLTGEIIFNGQSLTNLSTSALQQIRGKDISMIFQDPLSSLNPRLTIGKQITEVLFQHKRVSKSEAKSMTIDILEKVGIKHATRQFDAYPHELSGGMRQRVMIAMALILKPQILIADEPTTALDASTQNQLLQLMKSLYEYTETSIIFITHDLGAVYQFCDDVIVMKDGSVVESGTVESIFKSPQHTYTKRLIDAIPDIHQTRPPRPLNNDILLKFDRVSVDYKSPSGSLYRAVNDINLAIRKGETLGIVGESGSGKSTLAKTVVGLKEVSEGFIWYNELPLSLFKDDELKSLRQEIQMIFQDPFASINPRFKVIDVIKRPLIIHGKVKDNDDIIKTVVSLLEKVGLDQSFLYRYPHELSGGQRQRVSIARALAVEPKVIVCDEAVSALDVSIQKDIIELLKQLQLDFGITYLFITHDMGVINEICDRVAVMKNGEIVELNNTEDIIKHPQSDYAKQLISEVAVIAK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
Curr Res Microb Sci: 2025, 9;100489
[PubMed:41146725] [WorldCat.org] [DOI] (I e)