⊟Summary[edit | edit source]

PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
locus tag: SA_RS00205 [old locus tag: SA0012 ]
pan locus tag^?: SAUPAN000023000
symbol: SA_RS00205
pan gene symbol^?: —
• synonym:
• product: membrane protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS00205 [old locus tag: SA0012 ]
• symbol: SA_RS00205
• product: membrane protein
• replicon: chromosome
• strand: +
• coordinates: 17375..18313
• length: 939
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (17375..18313) NCBI
• BioCyc: SA_RS00205 BioCyc
• MicrobesOnline: see SA0012

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
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  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  
  ATGGGAGTGGCTTATGTGTTTTCAAAAATACAACCTAAAGCAACAATAATTGCAACGATT
  ACGTTGGTATTTGTCGCTTTAGCTTTATATCTAGTGCCTGGTTTGGGACTAATATTTGCA
  TTATTTGCAACCATACCAGGTATCGTTTTATGGAATAAATCAATACAATCTTTCGGGGTT
  AGTGCACTTATTACAGTAATTATAACAACTGTTTTAGGTAATACTTTCGTTTTAAGTGCC
  ATCATATTAGTCTTAATTGCAAGTTTAATTATTGGTCAATTGCTCAAAGAAAGAACGTCT
  AAAGAAAGAATGTTATACGTAACAACAGTAGCGATGAGCTTAATTTCATTAATCGCTTTT
  ATGTTACTACAAACATTCGGAAGGATTCCACCATCAGCGAGCATAGTAAAACCTTTCAAG
  CAAACATTACATGAAGCGATTACGATGAGCGGTGCCGATGCGAATATGACCCAAATATTA
  GAAGAAGGGTTTAGACAAGCGACCGTTCAATTACCAGGTTTCATCATTATCATTACATTT
  TTAATCGTCTTAATTAACTTAATCGTTACATTTCCGGTTTTACGAAAATTTAAAATCGCT
  ACACCTGTATTTAAGCCACTTTTCGCGTGGCAAATGAGCGGTATTTTATTATGGATATAC
  ATTATTGTTATCATATGTTTATTATTTACAGGTCAACCGAGTGTGTTCCAGAGCATTCTT
  TTAAACTTCCAACTTGTGTTATCATTAGTAATGTATATTCAAGGTTTAAGTGTTATTCAT
  TTCTTTGGTAAAGCGAAAGGTTTGCCGAATGCAGTAACGATTTTACTATTGATTATCGGT
  ACAATACTGACACCTACGACACATATTGTAGGACTACTTGGTGTTATCGATTTAAGTTTG
  AATTTGAAGCGAATCATGAAAAATAATTCTAAAAAGTGA
  60
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  939
  

⊟Protein

⊟General

• locus tag: SA_RS00205 [old locus tag: SA0012 ]
• symbol: SA_RS00205
• description: membrane protein
• length: 312
• theoretical pI: 10.8658
• theoretical MW: 34182.6
• GRAVY: 1.12821

⊟Function

• TIGRFAM:
• TheSEED: see SA0012
• ⊞⊞PFAM:
  no clan defined DUF2232; Predicted membrane protein (DUF2232) (PF09991; HMM-score: 218.2)
  and 1 more
  Herpes_US9; Alphaherpesvirus tegument protein US9 (PF06072; HMM-score: 9.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞⊞PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 7
• ⊞⊞DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0.0002
  • Cytoplasmic Membrane Score: 0.9985
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0012
• LocateP:
• ⊞⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.001869
  • TAT(Tat/SPI): 0.000192
  • LIPO(Sec/SPII): 0.006729
• predicted transmembrane helices (TMHMM): 7

⊟Accession numbers

• GI: 487716652 NCBI
• RefSeq: WP_001800884 NCBI
• UniProt: see SA0012

⊟Protein sequence

• MGVAYVFSKIQPKATIIATITLVFVALALYLVPGLGLIFALFATIPGIVLWNKSIQSFGVSALITVIITTVLGNTFVLSAIILVLIASLIIGQLLKERTSKERMLYVTTVAMSLISLIAFMLLQTFGRIPPSASIVKPFKQTLHEAITMSGADANMTQILEEGFRQATVQLPGFIIIITFLIVLINLIVTFPVLRKFKIATPVFKPLFAWQMSGILLWIYIIVIICLLFTGQPSVFQSILLNFQLVLSLVMYIQGLSVIHFFGKAKGLPNAVTILLLIIGTILTPTTHIVGLLGVIDLSLNLKRIMKNNSKK

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications