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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus COL

locus tag: SACOL_RS05970 [old locus tag: SACOL1168 ]

pan locus tag^?: SAUPAN003402000

symbol: SACOL_RS05970

pan gene symbol^?: efb

synonym:
product: fibrinogen-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SACOL_RS05970 [old locus tag: SACOL1168 ]
symbol: SACOL_RS05970
product: fibrinogen-binding protein
replicon: chromosome
strand: +
coordinates: 1176734..1177231
length: 498
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Location: NC_002951 (1176734..1177231) NCBI
BioCyc: SACOL_RS05970 BioCyc
MicrobesOnline: see SACOL1168

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

1
61
121
181
241
301
361
421
481
ATGAAAAATAAATTGATAGCAAAATCTTTATTAACATTAGCGGCAATAGGTATTACTACA
ACTACAATTGCGTCAACAGCAGATGCGAGCGAAGGATACGGTCCAAGAGAAAAGAAACCA
GTGAGTATTAATCACAATATCGTAGAGTACAATGATGGTACTTTTAAATATCAATCTAGA
CCAAAATTTAACTCAACACCTAAATATATTAAATTCAAACATGACTATAATATTTTAGAA
TTTAACGATGGTACATTCGAATATGGTGCACGTCCACAATTTAATAAACCAGCAGCGAAA
ACTGATGCAACTATTAAAAAAGAACAAAAATTGATTCAAGCTCAAAATCTTGTGAGAGAA
TTTGAAAAAACACATACTGTCAGTGCACACAGAAAAGCACAAAAGGCAGTCAACTTAGTT
TCGTTTGAATACAAAGTGAAGAAAATGGTCTTACAAGAGCGAATTGATAATGTATTAAAA
CAAGGATTAGTTAAATAA
60
120
180
240
300
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420
480
498

⊟Protein[edit | edit source]

Protein Data Bank: 1EFB

⊟General[edit | edit source]

locus tag: SACOL_RS05970 [old locus tag: SACOL1168 ]
symbol: SACOL_RS05970
description: fibrinogen-binding protein
length: 165
theoretical pI: 10.4514
theoretical MW: 18764.5
GRAVY: -0.632121

⊟Function[edit | edit source]

TIGRFAM:
TheSEED: see SACOL1168
PFAM:
no clan defined efb-c; Extracellular fibrinogen binding protein C terminal (PF12199; HMM-score: 130.8)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

⊞
PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.02
- Extracellular Score: 9.98
- Internal Helix: 1
⊞
DeepLocPro: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.0005
- Cell wall & surface Score: 0.1773
- Extracellular Score: 0.8221
LocateP:
⊞
SignalP: Signal peptide SP(Sec/SPI) length 29 aa
- SP(Sec/SPI): 0.991978
- TAT(Tat/SPI): 0.003351
- LIPO(Sec/SPII): 0.004114
- Cleavage Site: CS pos: 29-30. ADA-SE. Pr: 0.9025
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI: 446714256 NCBI
RefSeq: WP_000791587 NCBI
UniProt: see SACOL1168

⊟Protein sequence[edit | edit source]

MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK

⊟Experimental data[edit | edit source]

experimentally validated: see SACOL1168
protein localization: see SACOL1168
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator: SaeR see SACOL1168

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊞Biological Material[edit | edit source]

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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