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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus COL

locus tag: SACOL_RS00625 [old locus tag: SACOL0124 ]

pan locus tag^?: SAUPAN000951000

symbol: SACOL_RS00625

pan gene symbol^?: deoB

synonym:
product: phosphopentomutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SACOL_RS00625 [old locus tag: SACOL0124 ]
symbol: SACOL_RS00625
product: phosphopentomutase
replicon: chromosome
strand: +
coordinates: 139111..140289
length: 1179
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Location: NC_002951 (139111..140289) NCBI
BioCyc: SACOL_RS00625 BioCyc
MicrobesOnline: see SACOL0124

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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ATGACAAGACCATTTAATCGTGTACATTTAATCGTAATGGATTCAGTAGGTATTGGTGAA
GCGCCAGACGCAGCTGATTTTAAAGATGAAGGTTCACATACTTTAAGACATACCTTAGAA
GGTTTCGATCAAACTTTACCAAACCTTGAAAAGTTAGGTCTAGGGAACATCGATAAATTA
CCAGTAGTAAATGCAGTTGAACAACCAGAAGCATACTATACTAAATTGAGTGAAGCTTCA
GTTGGTAAAGATACAATGACTGGTCACTGGGAAATTATGGGATTAAATATTATGCAACCT
TTTAAAGTATACCCTAATGGATTCCCTGAAGAGTTAATTCAACAAATTGAAGAAATGACA
GGTCGTAAAGTTGTTGCTAACAAACCGGCATCGGGTACGCAAATTATCGATGAGTGGGGC
GAGCACCAAATGAAAACTGGTGACTTAATTGTTTATACAAGTGCAGACCCAGTATTGCAA
ATTGCTGCACATGAAGACATTATCCCATTAGAAGAGTTATATGATATTTGTGAAAAGGTT
CGTGAGTTGACAAAAGACCCTAAATATTTAATTGGTCGTATTATCGCACGTCCATATGTT
GGTGAACCAGGAAACTTTACACGTACATCTAATCGACATGACTATGCGTTAAAACCTTTT
GGTAAAACTGTCTTAGATCATTTGAAAGACGGTGGTTATGATGTTATTGCCATCGGTAAA
ATTAATGACATTTATGATGGTGAAGGTGTAACAGAAGCGGTTCGTACGAAGAGTAACATG
GACGGTATGGATCAATTGATGAAAATTGTTAAGAAAGATTTCACAGGTATTAGCTTCTTA
AACTTAGTAGACTTTGATGCATTATACGGTCATCGTCGTGATAAACCAGGTTATGCACAA
GCAATTAAAGATTTCGATGATCGCTTGCCAGAACTGTTTAGCAACTTAAAAGAAGACGAT
TTAGTAATTATTACAGCAGACCATGGTAATGACCCGACAGCGCCAGGTACGGACCATACG
AGAGAATATATCCCAGTAATTATGTACAGTCCGAAATTTAAAGGTGGTCATGCACTAGAA
AGTGATACTACATTCAGTTCTATCGGTGCAACTATAGCAGATAATTTCAACGTAACATTA
CCAGAGTTCGGTAAAAGTTATTTAAAGGAATTGAAATAG
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SACOL_RS00625 [old locus tag: SACOL0124 ]
symbol: SACOL_RS00625
description: phosphopentomutase
length: 392
theoretical pI: 4.76649
theoretical MW: 43795.3
GRAVY: -0.406122

⊟Function[edit | edit source]

⊞reaction:
EC 5.4.2.7? ExPASy
Phosphopentomutase Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate 2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate?
⊞TIGRFAM:
Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other phosphopentomutase (TIGR01696; EC 5.4.2.7; HMM-score: 743.7)
and 2 more
Metabolism Energy metabolism Glycolysis/gluconeogenesis phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (TIGR01307; EC 5.4.2.12; HMM-score: 22.3)
Metabolism Energy metabolism Glycolysis/gluconeogenesis phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form (TIGR00306; EC 5.4.2.12; HMM-score: 21.9)
TheSEED: see SACOL0124
⊞PFAM:
Alk_phosphatase (CL0088) Metalloenzyme; Metalloenzyme superfamily (PF01676; HMM-score: 160.4)
and 2 more
Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase (PF01663; HMM-score: 20.4)
Sulfatase; Sulfatase (PF00884; HMM-score: 14.1)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors: Mn²⁺
effectors:

⊟Localization[edit | edit source]

⊞
PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
⊞
DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9786
- Cytoplasmic Membrane Score: 0.0008
- Cell wall & surface Score: 0
- Extracellular Score: 0.0206
LocateP:
⊞
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.01247
- TAT(Tat/SPI): 0.001408
- LIPO(Sec/SPII): 0.001664
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI: 446119951 NCBI
RefSeq: WP_000197806 NCBI
UniProt: see SACOL0124

⊟Protein sequence[edit | edit source]

MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQTLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTGISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTAPGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK

⊟Experimental data[edit | edit source]

experimentally validated: see SACOL0124
protein localization: see SACOL0124
quantitative data / protein copy number per cell: see SACOL0124
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: see SACOL0124

⊟Protein stability[edit | edit source]

half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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