PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

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⊟Summary

• organism: Staphylococcus aureus NCTC8325
locus tag: SAOUHSC_00936
pan locus tag^?: SAUPAN003170000
symbol: SAOUHSC_00936
pan gene symbol^?: trfB
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAOUHSC_00936
• symbol: SAOUHSC_00936
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 908438..909424
• length: 987
• essential: no DEG other strains

⊟Accession numbers

• Gene ID: 3920765 NCBI
• RefSeq: YP_499489 NCBI
• BioCyc: G1I0R-878 BioCyc
• MicrobesOnline: 1289400 MicrobesOnline

⊟Phenotype

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⊟DNA sequence

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  ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTATTAGCAACTACTGCATTGAGAAAG
  ACACAATATTTTTGTCCGGTGTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTA
  ATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAATGTTTTAATAATGAAACGATT
  AAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
  GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAA
  TATGTTATTGAGCTACAGTATTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAA
  GGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAAATGATGTTGATTATTGTCAT
  AATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCATTCACTCGAAAACTT
  CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGC
  GGGCACAAATATGTCGCTGAAAAAAGAAATGCCAAAATTAGTGAGTTGTTTAATGAGGCG
  CCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCGCAATTAATCAATATATCAAA
  TATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
  TTAACTGATCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATT
  AAAAATCATCCTATTGAGTGGCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGC
  AAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAAAATTTATTGTTGCTCTAGAA
  AGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAAA
  GGTAATGACGTGCAAATTTTGTTCTAA
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⊟Protein

⊟General

• locus tag: SAOUHSC_00936
• symbol: SAOUHSC_00936
• description: hypothetical protein
• length: 328
• theoretical pI: 9.71608
• theoretical MW: 38840.3
• GRAVY: -0.335671

⊟Function

• TIGRFAM:
  acetoacetyl-CoA reductase (TIGR01829; EC 1.1.1.36; HMM-score: 14.3)
• TheSEED  :
  • Competence protein CoiA
  DNA Metabolism DNA uptake, competence Gram Positive Competence  Competence protein CoiA
• ⊞PFAM:
  PDDEXK (CL0236) CoiA; Competence protein CoiA-like family (PF06054; HMM-score: 103.5)
  and 3 more
  Zn_Beta_Ribbon (CL0167) HVO_2753_ZBP; Small zinc finger protein HVO_2753-like, Zn-binding pocket (PF07754; HMM-score: 13.2)
  Zn_ribbon_NOB1; Nin one binding (NOB1) Zn-ribbon like (PF08772; HMM-score: 13)
  C2H2-zf (CL0361) zf-Di19; Drought induced 19 protein (Di19), zinc-binding (PF05605; HMM-score: 12.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• ⊞DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9248
  • Cytoplasmic Membrane Score: 0.0388
  • Cell wall & surface Score: 0.003
  • Extracellular Score: 0.0335
• ⊞LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• ⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.006438
  • TAT(Tat/SPI): 0.001641
  • LIPO(Sec/SPII): 0.003812
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 88194693 NCBI
• RefSeq: YP_499489 NCBI
• UniProt: Q2G1U4 UniProt
• STRING: 93061.SAOUHSC_00936 STRING

⊟Protein sequence

• MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKVEIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPFTRKLHTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKISELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQLTDQEVVHNYGYIFPEQIYIKNHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDKGNDVQILF

⊟Experimental data

• experimentally validated:
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SAOUHSC_00936 > SAOUHSC_00937

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser:   
  
  ⊟Multi-gene expression profiles

  Compare with:

  Conditions

  Select all flucRPMI-exp RPMI-exp-A2 vancRPMI-exp RPMI-exp-A1 TSB-exp-A TSB-exp-C ciproTSB-exp T/SmxTSB-exp clindTSB-exp lineTSB-exp eryTSB-exp TSB-exp-B3 flucTSB-exp TSB-exp-B2 vancTSB-exp TSB-exp-B1 RPMI/FCS-exp colist-exp intTHP1-2h intTHP1-6h intS9-6h intS9-2h TSB-t2-C TSB-t4-C flucTSB-t4 TSB-t2-B1 TSB-t4-B1 CDM-t2 CDM-t4 T/SmxTSB-t4 TSB-t4-B3 lineTSB-t4 TSB-t4-B2 vancTSB-t4 eryTSB-t4 clindTSB-t4 ciproTSB-t4 pMEM-t2-C1 pMEM-t4-C1 CO2-6h CO2-2h anaer-2h nonad50-1h CO2-1h nonad25-1h pMEM-exp-C2 pMEM-exp-C1 CDM-exp plasma-t4 vancRPMI-t4 flucRPMI-t4 RPMI-t4-A2 RPMI-t2-A1 plasma-exp

  
  
  Click on any data point to display a description of the corresponding condition!

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications