PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

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⊟Summary

• organism: Staphylococcus aureus NCTC8325
locus tag: SAOUHSC_01583
pan locus tag^?: SAUPAN003962000
symbol: SAOUHSC_01583
pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAOUHSC_01583
• symbol: SAOUHSC_01583
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 1508540..1510567
• length: 2028
• essential: no DEG other strains

⊟Accession numbers

• Gene ID: 3919999 NCBI
• RefSeq: YP_500098 NCBI
• BioCyc: G1I0R-1471 BioCyc
• MicrobesOnline: 1290012 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  481
  541
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  661
  721
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  901
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  1021
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  1141
  1201
  1261
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  1441
  1501
  1561
  1621
  1681
  1741
  1801
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  1981
  
  ATGAATAAAATTAATGATAGGGATTTAACAGAATTAAGTAGTTACTGGGTTTATCAAAAT
  ATTGATATAAAAAAAGAATTTAAAGTTAATGGAAAAAGGTTTAAACAAGTAGACAGTTAT
  AATGATGATAAGAATAGTAATTTGAATGGTGCTGCTGATATTAAAATATATGAGTTATTA
  GATGATAAAAGTAAACCAACTGGTCAACAGACAATAATTTATCAAGGAACATCTAATGAG
  GCAATTAATCCAAATAATCCATTAAAATCATCGGGGTTTGGAGATGATTGGCTCCAAAAT
  GCTAAATTAATGAATAATGATAATGAAAGCACAGATTATTTAAAGCAAACAGATCAATTA
  TCAAATCAATATAAAATAAAGTTAGAAGATGCAGATAGATTATCAAATAGTGATTTTTTA
  AAAAAATATAGAATGGAATCAAGTAACTTCAAAAACAAAACCATTGTGGCGGATGGCGGT
  AATTCGGAAGGCGGTGCAGGAGCAAAATATCAAGGAGCGAAACATCCGAATGAAAAAGTT
  GTTGCTACTGACTCAGCAATGATTCCTTATGCTGCTTGGCAGAAATTTGCTAGACCACGC
  TTTGATAATATGATTAGTTTTAATAGTACCAACGATTTATTAACATGGTTACAAGATCCA
  TTCATCAAAGATATGCCAGGAAAACGCGTTAACATTAATGATGGTGTGCCCAGGTTAGAT
  ACTTTAATAGACAGCCATGTAGGTTATAAAAGGAAGTTAAATAGAAAAGATAACACATAC
  GATACTGTACCACTAATCAAAATAAAGTCGGTAAAAGATACAGAAATTAAAAATGGAAAA
  AAAGTAAAAAAGACTATTAACATAACATTAGATATGGATGGGCGAATTCCAATAAATGTT
  TGGACAGGAGATTCGATTGCACGTTCTGGAAGAGGAACTTTAATTAAACTTAATTTAGAA
  AATCTTGATGCGTTGAGTAAACTGATTACTGGTGAAACAAGTGGTATGTTAGCAGAATGC
  GTAATCTTTTTAAATGAAAGTTTTAACATCTCAGAAAATGAAAATAAAAATTTTGCAGAT
  AGAAAGAAACAATTATCAGAAGGATTTAAGGATAAGATTAACTTATTTCAGTTAGAAGAA
  ATGGAAAGAACTTTAATTAGTAAAATAAACTCACTTGAAGAAGTTGCAGATGAAACAATA
  GAAAGTATTAGTGCTGTTAAACACTTATTACCTGATTTTGCATTGGATGCATTAAAAGAA
  AGAATTAATGAGTTGTTTAAAGGTATAAAATCTTTTATAGAAAAAGTGTATGATAGTATA
  GATAATGAAATTTTAGAAATTTTCAAAAATATAGATCACGACTTCAGAGATGGAGTATCT
  GAAGAAATGATGAAACATTTGAAAGTAGTGAAACAGAATATAGACCAAATAAAAAATCAA
  AATGATATTTATGGTAGGCAAATTGCAGATATTAGAAGTATTATGAAACAACAAGATGCA
  ACAATTTTAGATGGAAATTTTCAAATTAATTGTAGCGGCGAAAATATGGTACAGGGTCTA
  GTTATACCTTCTAATTATTTAGGAAGAAAAATGAAAATATTAAAAGACCATATCGATGAT
  GGTATTAAAAAAATAGCAGACTATGTTCAAGGTATATATGATGAATATGCATCGAAAATT
  GTCGATGTAATAAAATATTTGATTAATACAATTCCCAAAATACGTAAGAATTTAAGACAT
  GCAATTGAAATGTTAAATGTAAAAAAGAAAGAATTTTTGTCCCTGATTCCTAATGTAACT
  TGTAATTATATTAAAACTAAATTAGAAGAATTAGATAATACTTTAGGCAAATGGGAGCCT
  TTTCTTAATGATTTAAAAGCAGTGTCACCAATTTTAGATAACCATTTAGATGATATTGTT
  AAGAACATGAAGCCTTTGATTGTACAAATGATATTTGAACCATCACATTATGACGATATG
  TTTAATTCAAGAAAAGCTTTAACGCCAGTGTTCTCAAGCGTTTTATAA
  60
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  2028
  

⊟Protein

⊟General

• locus tag: SAOUHSC_01583
• symbol: SAOUHSC_01583
• description: hypothetical protein
• length: 675
• theoretical pI: 6.81306
• theoretical MW: 77180.5
• GRAVY: -0.56637

⊟Function

• ⊞TIGRFAM:
  Cellular processes Cellular processes Detoxification formyl-CoA transferase (TIGR03253; EC 2.8.3.16; HMM-score: 16.5)
  and 1 more
  Cellular processes Cellular processes Sporulation and germination sporulation integral membrane protein YtvI (TIGR02872; HMM-score: 11.7)
• TheSEED  :
  • hypothetical protein within a prophage
• ⊞PFAM:
  no clan defined Baculo_PEP_C; Baculovirus polyhedron envelope protein, PEP, C terminus (PF04513; HMM-score: 24.9)
  and 7 more
  Prominin; Prominin (PF05478; HMM-score: 17)
  DUF7217; Domain of unknown function (DUF7217) (PF23854; HMM-score: 16.6)
  PsbQ-like (CL0752) CYP38_PsbQ-like; Peptidyl-prolyl cis-trans isomerase CYP38-like, PsbQ-like domain (PF21329; HMM-score: 10.4)
  no clan defined DUF4709; Domain of unknown function (DUF4709) (PF15821; HMM-score: 9.7)
  Lipoprotein_7; Adhesin lipoprotein (PF01540; HMM-score: 8.7)
  VPS23_C (CL0596) Mod_r; Modifier of rudimentary (Mod(r)) protein (PF07200; HMM-score: 8.1)
  RdRP (CL0027) Mitovir_RNA_pol; Mitovirus RNA-dependent RNA polymerase (PF05919; HMM-score: 7.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• ⊞DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.0002
  • Cytoplasmic Membrane Score: 0.0002
  • Cell wall & surface Score: 0.0003
  • Extracellular Score: 0.9992
• ⊞LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• ⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.019107
  • TAT(Tat/SPI): 0.001276
  • LIPO(Sec/SPII): 0.003102
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 88195294 NCBI
• RefSeq: YP_500098 NCBI
• UniProt: Q2FY82 UniProt
• STRING: 93061.SAOUHSC_01583 STRING

⊟Protein sequence

• MNKINDRDLTELSSYWVYQNIDIKKEFKVNGKRFKQVDSYNDDKNSNLNGAADIKIYELLDDKSKPTGQQTIIYQGTSNEAINPNNPLKSSGFGDDWLQNAKLMNNDNESTDYLKQTDQLSNQYKIKLEDADRLSNSDFLKKYRMESSNFKNKTIVADGGNSEGGAGAKYQGAKHPNEKVVATDSAMIPYAAWQKFARPRFDNMISFNSTNDLLTWLQDPFIKDMPGKRVNINDGVPRLDTLIDSHVGYKRKLNRKDNTYDTVPLIKIKSVKDTEIKNGKKVKKTINITLDMDGRIPINVWTGDSIARSGRGTLIKLNLENLDALSKLITGETSGMLAECVIFLNESFNISENENKNFADRKKQLSEGFKDKINLFQLEEMERTLISKINSLEEVADETIESISAVKHLLPDFALDALKERINELFKGIKSFIEKVYDSIDNEILEIFKNIDHDFRDGVSEEMMKHLKVVKQNIDQIKNQNDIYGRQIADIRSIMKQQDATILDGNFQINCSGENMVQGLVIPSNYLGRKMKILKDHIDDGIKKIADYVQGIYDEYASKIVDVIKYLINTIPKIRKNLRHAIEMLNVKKKEFLSLIPNVTCNYIKTKLEELDNTLGKWEPFLNDLKAVSPILDNHLDDIVKNMKPLIVQMIFEPSHYDDMFNSRKALTPVFSSVL

⊟Experimental data

• experimentally validated: data available for COL
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• predicted SigA promoter  : S636 < SAOUHSC_01583 < SAOUHSC_01584 < S637

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser:   
  
  ⊟Multi-gene expression profiles

  Compare with:

  Conditions

  Select all flucRPMI-exp RPMI-exp-A2 vancRPMI-exp RPMI-exp-A1 TSB-exp-A TSB-exp-C ciproTSB-exp T/SmxTSB-exp clindTSB-exp lineTSB-exp eryTSB-exp TSB-exp-B3 flucTSB-exp TSB-exp-B2 vancTSB-exp TSB-exp-B1 RPMI/FCS-exp colist-exp intTHP1-2h intTHP1-6h intS9-6h intS9-2h TSB-t2-C TSB-t4-C flucTSB-t4 TSB-t2-B1 TSB-t4-B1 CDM-t2 CDM-t4 T/SmxTSB-t4 TSB-t4-B3 lineTSB-t4 TSB-t4-B2 vancTSB-t4 eryTSB-t4 clindTSB-t4 ciproTSB-t4 pMEM-t2-C1 pMEM-t4-C1 CO2-6h CO2-2h anaer-2h nonad50-1h CO2-1h nonad25-1h pMEM-exp-C2 pMEM-exp-C1 CDM-exp plasma-t4 vancRPMI-t4 flucRPMI-t4 RPMI-t4-A2 RPMI-t2-A1 plasma-exp

  
  
  Click on any data point to display a description of the corresponding condition!

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications