From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06790 [old locus tag: SA1194 ]
  • pan locus tag?: SAUPAN003750000
  • symbol: SA_RS06790
  • pan gene symbol?: msrA2
  • synonym:
  • product: peptide-methionine (S)-S-oxide reductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS06790 [old locus tag: SA1194 ]
  • symbol: SA_RS06790
  • product: peptide-methionine (S)-S-oxide reductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1366337..1366846
  • length: 510
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1366337..1366846) NCBI
  • BioCyc: SA_RS06790 BioCyc
  • MicrobesOnline: see SA1194

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATATTAATACAGCTTATTTTGCCGGAGGTTGCTTTTGGTGTATGACGAAACCATTT
    GACACCTTTGACGGCATAGAAAAAGTAACTTCTGGATATATGGGCGGACATATTGAAAAT
    CCTACTTACGAACAAGTAAAATCAGGTACGAGTGGTCATTTAGAAACTGTTGAAATTCAA
    TATGATGTTGCATTATTCTCATACAATAAGTTATTAGAAATATTTTTCTCAGTCATTGAC
    CCATTAGATACAGGTGGTCAATATCAAGACCGTGGTCCTCAATATCAAACAGCTATTTTC
    TACACTAATGATCATCAAAAAGAACTCGCTGAGACATATATCGAGCAGCTTAAAAATACG
    ATTAATGCTGATAAGGCAATTGCAACAAAAATATTACCAGCGTCACAATTTTACAAAGCC
    GAAGACTATCACCAAGATTTTTATAAGAAAAATCCAGAGCGCTATGCAGAAGAACAAAAA
    ATACGCCAAGAATACAAAAATAAGCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    510

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS06790 [old locus tag: SA1194 ]
  • symbol: SA_RS06790
  • description: peptide-methionine (S)-S-oxide reductase
  • length: 169
  • theoretical pI: 4.86349
  • theoretical MW: 19610.7
  • GRAVY: -0.739645

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 1.8.4.11?  ExPASy
    Peptide-methionine (S)-S-oxide reductase Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin
  • TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions peptide-methionine (S)-S-oxide reductase (TIGR00401; EC 1.8.4.11; HMM-score: 188.7)
    Genetic information processing Protein fate Protein modification and repair peptide-methionine (S)-S-oxide reductase (TIGR00401; EC 1.8.4.11; HMM-score: 188.7)
  • TheSEED: see SA1194
  • ⊞PFAM:
    no clan defined PMSR; Peptide methionine sulfoxide reductase (PF01625; HMM-score: 207)
    and 2 more
    RCDG1; Renal cancer differentiation gene 1 protein (PF15725; HMM-score: 14.4)
    DUF4298; Domain of unknown function (DUF4298) (PF14131; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.992
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0073
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.047787
    • TAT(Tat/SPI): 0.000356
    • LIPO(Sec/SPII): 0.012765
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQKIRQEYKNKQ

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://fungenwikiserver.biologie.uni-greifswald.de/aureowiki/index.php?title=SA_RS06790&oldid=86462"