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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2078 [new locus tag: SACOL_RS10870 ]
  • pan locus tag?: SAUPAN005363000
  • symbol: SACOL2078
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2078 [new locus tag: SACOL_RS10870 ]
  • symbol: SACOL2078
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2144193..2144486
  • length: 294
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGT
    TTAAATCGAATTGAAGGACAAGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTAT
    TGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGGCGTTAAACAGTGTTGCGATA
    AAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
    GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA
    60
    120
    180
    240
    294

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2078 [new locus tag: SACOL_RS10870 ]
  • symbol: SACOL2078
  • description: hypothetical protein
  • length: 97
  • theoretical pI: 6.24941
  • theoretical MW: 11197.8
  • GRAVY: -0.548454

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General zinc finger protein ZPR1 homolog (TIGR00340; HMM-score: 14.1)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage terminase, large subunit, PBSX family (TIGR01547; HMM-score: 12.8)
  • TheSEED  :
    • FIG01108056: hypothetical protein
  • ⊞PFAM:
    no clan defined Trns_repr_metal; Metal-sensitive transcriptional repressor (PF02583; HMM-score: 98.2)
    and 5 more
    TPR (CL0020) DHR-2_Lobe_C; DHR-2, Lobe C (PF20421; HMM-score: 16.7)
    SPO22; Meiosis protein SPO22/ZIP4 like (PF08631; HMM-score: 14.4)
    no clan defined CdaS_N; Diadenylate cyclase CdaS, N-terminal (PF10372; HMM-score: 14.1)
    Herpes_UL14; Herpesvirus UL14-like protein (PF03580; HMM-score: 12.8)
    AvrE_T3Es; AvrE-family Type-III effector proteins (T3Es) (PF11725; HMM-score: 10.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.986
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.0127
  • ⊞LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003419
    • TAT(Tat/SPI): 0.000516
    • LIPO(Sec/SPII): 0.000463
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVAIKLLEQHMKSCIMNKVNQGAQEEAMEELLVTFQKLIKD

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Cytoplasmic [1] [2]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)
  2. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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