PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

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⊟Summary

• organism: Staphylococcus aureus N315
locus tag: SA1750
pan locus tag^?: SAUPAN005008000
symbol: SA1750
pan gene symbol^?: map_2
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA1750
• symbol: SA1750
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 2003028..2003348
• length: 321
• essential: no DEG other strains

⊟Accession numbers

• Gene ID: 3251082 NCBI
• RefSeq: NP_375044 NCBI
• BioCyc:
• MicrobesOnline: 104070 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  
  ATCAAAAAAAAAATAAATAAATCTAATAATGTGAAATTCCCAGTAACAATAAATAAATTT
  GAAAACATAGTTTCAAATGAATTTGTGTTCTATAATGCAAGCAAAATTACAATTAATGAT
  TTAAGTATAAAACTTAAATCAGCAATGGCAAATGATCAAGGGATAACTAAACATGACATA
  GGACTTGCTGAACGCGCAGTGTATAAAGTGTATTTTAAAAATGGTTCGTCAAAATATGTA
  GACTTAAAAACTGAGTATAAAGATGAAAGAGTATTTAAAGCAACTGACATTAAAAAGGTA
  GATATTGAACTTAAATTCTAA
  60
  120
  180
  240
  300
  321
  

⊟Protein

⊟General

• locus tag: SA1750
• symbol: SA1750
• description: hypothetical protein
• length: 106
• theoretical pI: 10.2408
• theoretical MW: 12260.1
• GRAVY: -0.49717

⊟Function

• TIGRFAM:
• TheSEED  :
  • Extracellular adherence protein of broad specificity Eap/Map
  Virulence, Disease and Defense Adhesion Adhesins in Staphylococcus  Extracellular adherence protein of broad specificity Eap/Map
• ⊞PFAM:
  no clan defined MAP; MAP domain (PF03642; HMM-score: 121)
  and 1 more
  Ubiquitin (CL0072) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 16.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0.17
  • Cytoplasmic Membrane Score: 9.51
  • Cellwall Score: 0.16
  • Extracellular Score: 0.15
  • Internal Helices: 0
• ⊞DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.3465
  • Cytoplasmic Membrane Score: 0.0059
  • Cell wall & surface Score: 0.0008
  • Extracellular Score: 0.6467
• ⊞LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• ⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.048781
  • TAT(Tat/SPI): 0.000305
  • LIPO(Sec/SPII): 0.000494
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15927511 NCBI
• RefSeq: NP_375044 NCBI
• UniProt:

⊟Protein sequence

• MKKKINKSNNVKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDERVFKATDIKKVDIELKF

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SA1750 < SA1751

⊟Regulation

• ⊞regulator: SaeR (activation) regulon

  SaeR

  (TF)

  important in Virulence; RegPrecise

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications