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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0403 [new locus tag: SA_RS02305 ]
  • pan locus tag?: SAUPAN002142000
  • symbol: lpl7
  • pan gene symbol?: lpl3
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA0403 [new locus tag: SA_RS02305 ]
  • symbol: lpl7
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 462906..463706
  • length: 801
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGGGATATTTTAAAAGAGTTGTACTTTACATAATTGTTATGGTTGTGAGTGTTTTTATA
    ATAGGTTGCAATAAATCAAGCGATACTTCAGAAAAGCCAAAAGAAGATTCAAAAGAAACA
    CAAATCAAAAAGAGCTTTGCGAAAACGTTAGATATGTATCCAATTAAGAATCTCGAGGAC
    TTATATGATAAAGAAGGATACCGTGATGGCGAATTTAAAAAGGGTGACAAAGGAATGTGG
    ACTATATATACAGATTTTGCTAAAAGTAATAAACAAGGTGGATTGAGTAATGAAGGTATG
    GTCTTATACTTAGATAGAAATACACGGACTGCAAAGGGACATTATTTTGTTAAGACATTC
    TATAATAAGGGCAAATTCCCAGATAGAAAAAATTATAAAGTTGAAATGAAAAATAATAAA
    ATTATCTTATTAGATAAAGTAGAAGATATAAATCTAAAAAAGAGAATAGAAAACTTTAAA
    TTTTTTGGACAATATGCAAATCTTAAAGAATTGAAAAATTACAGCAATGGTGATGTCTCA
    ATTAATGAGAATGTTCCAAGTTATGACGCAAAATTTAAAATGAGCAATAAAGATGAAAAT
    GTTAAGCAATTAAGAAGTCGTTATAATATTCCTACTGATAAAGCACCGGTATTAAAAATG
    CATATTGATGGTGATTTGAAAGGAAGTTCTGTGGGTTATAAAAAGTTGGAAATTGACTTT
    TCAAAAGGTGAAAAAAGCGATTTGTCAGTAATAGATTCTTTAAATTTCCAGCCGGCGAAG
    GTGGATGAAGATGATGAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    801

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA0403 [new locus tag: SA_RS02305 ]
  • symbol: Lpl7
  • description: hypothetical protein
  • length: 266
  • theoretical pI: 9.60985
  • theoretical MW: 30767.9
  • GRAVY: -0.796617

⊟Function[edit | edit source]

  • TIGRFAM:
    Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 404.4)
  • TheSEED  :
    • Tandem lipoprotein within Pathogenicity island
  • ⊞PFAM:
    LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 332.5)
    and 3 more
    no clan defined DUF4972; Domain of unknown function (DUF4972) (PF16342; HMM-score: 13.5)
    PsbI; Photosystem II reaction centre I protein (PSII 4.8 kDa protein) (PF02532; HMM-score: 12.1)
    P-loop_NTPase (CL0023) Bac_DnaA; Bacterial DnaA ATPAse domain (PF00308; HMM-score: 10.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • ⊞DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0003
    • Cytoplasmic Membrane Score: 0.3237
    • Cell wall & surface Score: 0.0006
    • Extracellular Score: 0.6755
  • ⊞LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: VFIIGCN
  • ⊞SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
    • SP(Sec/SPI): 0.000512
    • TAT(Tat/SPI): 0.000057
    • LIPO(Sec/SPII): 0.999206
    • Cleavage Site: CS pos: 22-23. IIG-CN. Pr: 0.9997
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MGYFKRVVLYIIVMVVSVFIIGCNKSSDTSEKPKEDSKETQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGMWTIYTDFAKSNKQGGLSNEGMVLYLDRNTRTAKGHYFVKTFYNKGKFPDRKNYKVEMKNNKIILLDKVEDINLKKRIENFKFFGQYANLKELKNYSNGDVSINENVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPVLKMHIDGDLKGSSVGYKKLEIDFSKGEKSDLSVIDSLNFQPAKVDEDDE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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