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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS11140 [old locus tag: SA1939 ]
  • pan locus tag?: SAUPAN005434000
  • symbol: SA_RS11140
  • pan gene symbol?: deoC2
  • synonym:
  • product: 2-deoxyribose-5-phosphate aldolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS11140 [old locus tag: SA1939 ]
  • symbol: SA_RS11140
  • product: 2-deoxyribose-5-phosphate aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2188926..2189588
  • length: 663
  • essential: yes [1] DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2188926..2189588) NCBI
  • BioCyc: SA_RS11140 BioCyc
  • MicrobesOnline: see SA1939

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAATAGTGCAAAATTGATTGATCACACTTTATTGAAGCCTGAGTCAACACGTACGCAA
    ATCGATCAAATCATCGATGAAGCGAAAGCATACCATTTTAAATCTGTATGTGTGAATCCA
    ACGCATGTTAAATATGCAGCAGAGCGACTAGCTGATTCAGAGGTGTTAGTTTGTACGGTA
    ATAGGATTCCCATTAGGTGCATCGACAACTGCGACGAAAGCATTTGAAACAGAAGATGCG
    ATTCAAAATGGTGCAGATGAAATTGACATGGTCATCAACATCGGCGCATTAAAAGATGGA
    CGTTTTGATGATGTACAACAAGACATTGAAGCAGTGGTGAAAGCTGCGAAAGGTCACACA
    GTAAAAGTGATTATTGAGACGGTATTGTTGGACCATGACGAAATCGTAAAAGCGAGTGAA
    TTAACAAAAGTGGCTGGTGCGGACTTCGTTAAAACTTCAACAGGTTTTGCAGGTGGCGGT
    GCGACTGCAGAAGACGTTAAATTAATGAAAGATACAGTAGGTGCTGATGTAGAAGTAAAA
    GCATCAGGTGGCGTACGTAATTTAGAAGATTTCAATAAAATGGTTGAAGCAGGTGCGACA
    CGTATTGGTGCGAGCGCAGGCGTTCAAATTATGCAAGGTTTAGAAGCAGATTCAGATTAC
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    663

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS11140 [old locus tag: SA1939 ]
  • symbol: SA_RS11140
  • description: 2-deoxyribose-5-phosphate aldolase
  • length: 220
  • theoretical pI: 4.47623
  • theoretical MW: 23341.2
  • GRAVY: -0.0640909

⊟Function[edit | edit source]

  • ⊞⊞reaction:
    EC 4.1.2.4?  ExPASy
    Deoxyribose-phosphate aldolase 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
  • ⊞⊞TIGRFAM:
    Metabolism Energy metabolism Other deoxyribose-phosphate aldolase (TIGR00126; EC 4.1.2.4; HMM-score: 286.3)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other deoxyribose-phosphate aldolase (TIGR00126; EC 4.1.2.4; HMM-score: 286.3)
    and 1 more
    predicted phospho-2-dehydro-3-deoxyheptonate aldolase (TIGR01949; EC 4.2.1.-; HMM-score: 18.5)
  • TheSEED: see SA1939
  • ⊞⊞PFAM:
    TIM_barrel (CL0036) DeoC; DeoC/LacD family aldolase (PF01791; HMM-score: 92.2)
    and 2 more
    His_biosynth; Histidine biosynthesis protein (PF00977; HMM-score: 16.3)
    G3P_antiterm; Glycerol-3-phosphate responsive antiterminator (PF04309; HMM-score: 14.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9987
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0011
  • LocateP:
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014554
    • TAT(Tat/SPI): 0.000358
    • LIPO(Sec/SPII): 0.000808
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ R Allyn Forsyth, Robert J Haselbeck, Kari L Ohlsen, Robert T Yamamoto, Howard Xu, John D Trawick, Daniel Wall, Liangsu Wang, Vickie Brown-Driver, Jamie M Froelich, Kedar G C, Paula King, Melissa McCarthy, Cheryl Malone, Brian Misiner, David Robbins, Zehui Tan, Zhan-yang Zhu Zy, Grant Carr, Deborah A Mosca, Carlos Zamudio, J Gordon Foulkes, Judith W Zyskind
    A genome-wide strategy for the identification of essential genes in Staphylococcus aureus.
    Mol Microbiol: 2002, 43(6);1387-400
    [PubMed:11952893] [WorldCat.org] [DOI] (P p)

⊟Relevant publications[edit | edit source]

Retrieved from "http://fungenwikiserver.biologie.uni-greifswald.de/aureowiki/index.php?title=SA_RS11140&oldid=90055"
Insert paragraph

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS11140 [old locus tag: SA1939 ]
  • pan locus tag?: SAUPAN005434000
  • symbol: SA_RS11140
  • pan gene symbol?: deoC2
  • synonym:
  • product: 2-deoxyribose-5-phosphate aldolase

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS11140 [old locus tag: SA1939 ]
  • symbol: SA_RS11140
  • product: 2-deoxyribose-5-phosphate aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2188926..2189588
  • length: 663
  • essential: yes [1] DEG other strains

  1. ↑ R Allyn Forsyth, Robert J Haselbeck, Kari L Ohlsen, Robert T Yamamoto, Howard Xu, John D Trawick, Daniel Wall, Liangsu Wang, Vickie Brown-Driver, Jamie M Froelich, Kedar G C, Paula King, Melissa McCarthy, Cheryl Malone, Brian Misiner, David Robbins, Zehui Tan, Zhan-yang Zhu Zy, Grant Carr, Deborah A Mosca, Carlos Zamudio, J Gordon Foulkes, Judith W Zyskind
    A genome-wide strategy for the identification of essential genes in Staphylococcus aureus.
    Mol Microbiol: 2002, 43(6);1387-400
    [PubMed:11952893] [WorldCat.org] [DOI] (P p)
Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2188926..2189588) NCBI
  • BioCyc: SA_RS11140 BioCyc
  • MicrobesOnline: see SA1939

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAATAGTGCAAAATTGATTGATCACACTTTATTGAAGCCTGAGTCAACACGTACGCAA
    ATCGATCAAATCATCGATGAAGCGAAAGCATACCATTTTAAATCTGTATGTGTGAATCCA
    ACGCATGTTAAATATGCAGCAGAGCGACTAGCTGATTCAGAGGTGTTAGTTTGTACGGTA
    ATAGGATTCCCATTAGGTGCATCGACAACTGCGACGAAAGCATTTGAAACAGAAGATGCG
    ATTCAAAATGGTGCAGATGAAATTGACATGGTCATCAACATCGGCGCATTAAAAGATGGA
    CGTTTTGATGATGTACAACAAGACATTGAAGCAGTGGTGAAAGCTGCGAAAGGTCACACA
    GTAAAAGTGATTATTGAGACGGTATTGTTGGACCATGACGAAATCGTAAAAGCGAGTGAA
    TTAACAAAAGTGGCTGGTGCGGACTTCGTTAAAACTTCAACAGGTTTTGCAGGTGGCGGT
    GCGACTGCAGAAGACGTTAAATTAATGAAAGATACAGTAGGTGCTGATGTAGAAGTAAAA
    GCATCAGGTGGCGTACGTAATTTAGAAGATTTCAATAAAATGGTTGAAGCAGGTGCGACA
    CGTATTGGTGCGAGCGCAGGCGTTCAAATTATGCAAGGTTTAGAAGCAGATTCAGATTAC
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    663

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS11140 [old locus tag: SA1939 ]
  • symbol: SA_RS11140
  • description: 2-deoxyribose-5-phosphate aldolase
  • length: 220
  • theoretical pI: 4.47623
  • theoretical MW: 23341.2
  • GRAVY: -0.0640909

Insert paragraph

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 4.1.2.4?  ExPASy
    Deoxyribose-phosphate aldolase 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
  • ⊞TIGRFAM:
    Metabolism Energy metabolism Other deoxyribose-phosphate aldolase (TIGR00126; EC 4.1.2.4; HMM-score: 286.3)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other deoxyribose-phosphate aldolase (TIGR00126; EC 4.1.2.4; HMM-score: 286.3)
    and 1 more
    predicted phospho-2-dehydro-3-deoxyheptonate aldolase (TIGR01949; EC 4.2.1.-; HMM-score: 18.5)
  • TheSEED: see SA1939
  • ⊞PFAM:
    TIM_barrel (CL0036) DeoC; DeoC/LacD family aldolase (PF01791; HMM-score: 92.2)
    and 2 more
    His_biosynth; Histidine biosynthesis protein (PF00977; HMM-score: 16.3)
    G3P_antiterm; Glycerol-3-phosphate responsive antiterminator (PF04309; HMM-score: 14.7)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9987
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0011
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014554
    • TAT(Tat/SPI): 0.000358
    • LIPO(Sec/SPII): 0.000808
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY

Insert paragraph

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

Insert paragraph

⊟Transcription pattern[edit | edit source]

Insert paragraph

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Insert paragraph

⊟Protein stability[edit | edit source]

  • half-life: no data available

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph