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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06455 [old locus tag: SA1143 ]
  • pan locus tag?: SAUPAN003615000
  • symbol: SA_RS06455
  • pan gene symbol?: —
  • synonym:
  • product: alpha/beta hydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS06455 [old locus tag: SA1143 ]
  • symbol: SA_RS06455
  • product: alpha/beta hydrolase
  • replicon: chromosome
  • strand: +
  • coordinates: 1301115..1302029
  • length: 915
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1301115..1302029) NCBI
  • BioCyc: SA_RS06455 BioCyc
  • MicrobesOnline: see SA1143

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGACTGAAAAACAATTTAAATTAACTGTACAAGATAATACGAATATTGAAGTTAAAGTG
    AATTTTACAGATGTAGATTCAAAAGGAATTATTCATATATTTCATGGTATGGCTGAACAT
    ATGGAACGTTACGATAAATTAGCACATGCACTTTCAAAGCATGGCTTCGATGTGATACGT
    CATAATCATCGAGGACATGGTATTAATATTGATGAATCAACAAGAGGGCATTACGATGAT
    ATGAAACGAGTTATCGGTGATGCCTTTGAAGTAGCGCAAACAGTGAGAGGCAATGTTGAT
    AAACCATACATTATAATCGGACATTCAATGGGATCCGTTATAGCTAGATTGTTTGTAGAA
    ACATATCCGCAATATGTTGATGGTCTAATTTTAAGTGGTACTGGTATGTATTCATTATGG
    AAAGGTTTACCAACCGTTAAAGTGTTACAACTGATTACAAAAATTTATGGTGCTGAGAAA
    CGAGTTGAATGGGTTAACCAGTTAGTATCAAATAGTTTTAATAAAAAAATACGTCCATTA
    CGTACACAAAGTGATTGGATTTCTAGTAATCCAATTGAAGTAGATAACTTTATTAAAGAT
    CCATATAGTGGATTTAATGTGTCAAATCAATTATTATATCAAACAGCCTATTATATGCTA
    CATACATCACAATTAAAAAATATGAAAATGTTAAATCATGCCATGCCTATATTATTAGTT
    TCAGGATATGACGATTCTTTAGGTGATTATGGTAAAGGGATTTTAAAATTGGCGAATATA
    TATAGAAAAGCTGGCATTAAAAATGTTAAAGTGAATCTTTATCATCATAAACGTCATGAA
    GTGTTATTTGAAAAAGATCATGACAAAATTTGGGAAGACTTGTTTAAATGGTTGAATCAA
    TTTTATAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    915

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS06455 [old locus tag: SA1143 ]
  • symbol: SA_RS06455
  • description: alpha/beta hydrolase
  • length: 304
  • theoretical pI: 9.65305
  • theoretical MW: 35245.2
  • GRAVY: -0.416776

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (TIGR03695; EC 4.2.99.20; HMM-score: 35)
    and 5 more
    Metabolism Energy metabolism Other 3-oxoadipate enol-lactonase (TIGR02427; EC 3.1.1.24; HMM-score: 25)
    2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (TIGR03343; EC 3.7.1.-; HMM-score: 24.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin pimelyl-[acyl-carrier protein] methyl ester esterase (TIGR01738; EC 3.1.1.85; HMM-score: 24)
    proline-specific peptidase (TIGR01250; HMM-score: 23.1)
    Metabolism Energy metabolism Photosynthesis putative magnesium chelatase accessory protein (TIGR03056; HMM-score: 14.4)
  • TheSEED: see SA1143
  • ⊞PFAM:
    AB_hydrolase (CL0028) Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 158.7)
    and 12 more
    Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 79.5)
    Abhydrolase_6; Alpha/beta hydrolase family (PF12697; HMM-score: 30.9)
    Abhydrolase_11; Alpha/beta hydrolase domain (PF20408; HMM-score: 28.8)
    Palm_thioest; Palmitoyl protein thioesterase (PF02089; HMM-score: 22.3)
    Peptidase_S28; Serine carboxypeptidase S28 (PF05577; HMM-score: 18.1)
    LIDHydrolase; Lipid-droplet associated hydrolase (PF10230; HMM-score: 17.2)
    Abhydrolase_5; Alpha/beta hydrolase family (PF12695; HMM-score: 16.4)
    PGAP1; PGAP1-like alpha/beta domain (PF07819; HMM-score: 16.1)
    Thioesterase; Thioesterase domain (PF00975; HMM-score: 16)
    Cas9_WED-like (CL0790) CRISPR_Cas9_WED; CRISPR-Cas9 WED domain (PF18061; HMM-score: 15.6)
    AB_hydrolase (CL0028) Acyl_transf_2; Acyl transferase (PF02273; HMM-score: 15)
    LCAT; Lecithin:cholesterol acyltransferase (PF02450; HMM-score: 14.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.4317
    • Cytoplasmic Membrane Score: 0.4939
    • Cell wall & surface Score: 0.0044
    • Extracellular Score: 0.0699
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004024
    • TAT(Tat/SPI): 0.00026
    • LIPO(Sec/SPII): 0.000268
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTEKQFKLTVQDNTNIEVKVNFTDVDSKGIIHIFHGMAEHMERYDKLAHALSKHGFDVIRHNHRGHGINIDESTRGHYDDMKRVIGDAFEVAQTVRGNVDKPYIIIGHSMGSVIARLFVETYPQYVDGLILSGTGMYSLWKGLPTVKVLQLITKIYGAEKRVEWVNQLVSNSFNKKIRPLRTQSDWISSNPIEVDNFIKDPYSGFNVSNQLLYQTAYYMLHTSQLKNMKMLNHAMPILLVSGYDDSLGDYGKGILKLANIYRKAGIKNVKVNLYHHKRHEVLFEKDHDKIWEDLFKWLNQFYKK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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