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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS12435 [old locus tag: SACOL2368 ]
  • pan locus tag?: SAUPAN005889000
  • symbol: SACOL_RS12435
  • pan gene symbol?: —
  • synonym:
  • product: N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS12435 [old locus tag: SACOL2368 ]
  • symbol: SACOL_RS12435
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 2428786..2429121
  • length: 336
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2428786..2429121) NCBI
  • BioCyc: SACOL_RS12435 BioCyc
  • MicrobesOnline: see SACOL2368

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGAGTCCAAAGACGCGCGAAGCAGCTGAAAAAGGATTACCTAATGCCTTATTTACAGTA
    ACCTTGTATGATAAAGATCGGTTAATTGGTATGGGTAGAGTGATTGGCGATGGCGGAACT
    GTTTTTCAAATTGTTGATATTGCAGTTTTGAAAAGTTACCAAGGTCAAGGTTACGGCAGT
    CTAATTATGGAGCATATTATGCAATATATTAAAGGTGTGGCTGTTGAGAGTACATACGTT
    AGTCTGATTGCAGACTACCCAGCGGATAAATTATATACAAAATTTGGATTTATACCTACC
    GAACCAGATTCAGGCGGTATGTATATCAAATACTAA
    60
    120
    180
    240
    300
    336

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS12435 [old locus tag: SACOL2368 ]
  • symbol: SACOL_RS12435
  • description: N-acetyltransferase
  • length: 111
  • theoretical pI: 5.83017
  • theoretical MW: 12225.1
  • GRAVY: 0.0027027

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 30.9)
  • TheSEED: see SACOL2368
  • ⊞PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 49.9)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 49.6)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 46.5)
    and 5 more
    FR47; FR47-like protein (PF08445; HMM-score: 24)
    GNAT_acetyltr_2; GNAT acetyltransferase 2 (PF13718; HMM-score: 20.7)
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 17)
    IDM1_C; Increased DNA methylation 1, C-terminal (PF23209; HMM-score: 14.8)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 13.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9288
    • Cytoplasmic Membrane Score: 0.002
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.069
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005718
    • TAT(Tat/SPI): 0.000247
    • LIPO(Sec/SPII): 0.000712
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSPKTREAAEKGLPNALFTVTLYDKDRLIGMGRVIGDGGTVFQIVDIAVLKSYQGQGYGSLIMEHIMQYIKGVAVESTYVSLIADYPADKLYTKFGFIPTEPDSGGMYIKY

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2368
  • protein localization: see SACOL2368
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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