PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS12980 [old locus tag: SA2261 ]
• pan locus tag^?: SAUPAN006037000
• symbol: SA_RS12980
• pan gene symbol^?: —
• synonym:
• product: aminobenzoyl-glutamate transporter

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS12980 [old locus tag: SA2261 ]
• symbol: SA_RS12980
• product: aminobenzoyl-glutamate transporter
• replicon: chromosome
• strand: +
• coordinates: 2538750..2540288
• length: 1539
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (2538750..2540288) NCBI
• BioCyc: SA_RS12980 BioCyc
• MicrobesOnline: see SA2261

⊟Phenotype

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⊟DNA sequence

• 1
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  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  1501
  
  ATGACATCAAAACATCAACAAAAGGGGTCTATCGTCAATCGTTTCTTGAATAGTGTTGAA
  AAAATTGGAAATAAATTGCCAGATCCTAGCGTCTTATTCTTTTTAATGTGTGTGGGCTTA
  GCCATTATGACGTGGGTTATCTCATTATTTAATGTATCTGTTAAGCATCCAGGTACGCAT
  CAAACCATTTATATTAAAAATATAATTAGCCATGATGGATTTACGATGATAATGAATGAT
  ACGATTAAAAATTTCTCAGAGTTCCCAGCATTAGGCTTAGTACTAGCAGTGATGATTGGT
  ATTGGTGTTGCAGAGAAAACAGGATACTTCGATAAGTTAATGATTTCTGTTGTGAATCGC
  GCACCACGATTTTTAATTTTACCGACTATTATATTAATTGGTATTTTAGGTAGTACAGCC
  GGCGATGCTGCGACAATTATCTTGCCGCCGCTTGCAGCAATGCTTTTTATTAAAATTGGC
  TATCACCCTATTGCTGGTTTAACGATGGCATATGCTTCCGCTGTTGGAGGATTTGCAGCA
  AATATAGTTGTTGGTATGCAAGATGCTTTGGTCTATTCATTTACAGAACCGGCAACACGT
  ATCGTTTCAGATTCTATTAAAACAAACGTTGCTATGAACTGGTACTTTATCGCAGCGAGT
  GTCGTTGTATTACTTCCTACGATATTGCTAGTTACAACTAAGCTCATTATTCCTAGATTA
  GGAAAATATGATGACAGTTTAATGCATGATGACCATGAAGAAGCATCTTCACATATTACT
  GACAAAGAAGCACATGCTTTAAAATGGGCAAATATCAGTTTCATAGTCACAATTATTTTA
  TTAATTATTACAGCTATTCCTGAACATAGTTTTTTAAGAAATGCTAAAACAGGCAGCTTA
  CTAGACGATGCGCCATTAATTAACGGTGTCGGATTAATTATTCTTGTCGTATTTTTAGTA
  CCTGGATTAGTTTATGGGATTTTAAGCAAAGAAATTAAAAATACAAAAGACTTAGGTAAA
  ATGTTCGGCGATGCTGTAGGATCAATGGGAACATTTATCGTTATTGTGTTTTTTGCAGCA
  CAGCTACTTGCGTATTTAAAGTGGAGTAATTTAGGAATTATCGCTGCTGTTAAAGGTGCC
  AAATTATTAGAACATCAAAACGGTATTGTATTGATACTAGGTATTATTGTACTGAGTGCA
  ATGGTCAACATGTTAATCGGAAGCGCATCGGCTAAATGGGGTATTTTAGGACCGATATTC
  GTACCAATGTTAATCCTTATCGGCTTTCATCCCGCATTTACGCAAGTCATTTACCGTGTA
  GGCGATTCAATTACCAATCCAATTACACCGATGATGCCGTACTTACCTTTATTATTAACT
  TATGCACAAAAATACGATAAACGCATGAAACTCGGAGCCTTACTTTCTAGTTTAATGCCG
  TATTCAATCGCGCTAAGCATTGTATGGACAGTATTTGTCATCATTTGGTTCTTATTAGGT
  ATCCCTGTTGGACCAGGTGGACCGATATTCGTTAAATAA
  60
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  1539
  

⊟Protein

⊟General

• locus tag: SA_RS12980 [old locus tag: SA2261 ]
• symbol: SA_RS12980
• description: aminobenzoyl-glutamate transporter
• length: 512
• theoretical pI: 9.7071
• theoretical MW: 55544.2
• GRAVY: 0.780273

⊟Function

• TIGRFAM:
  Hypothetical proteins Conserved AbgT transporter family (TIGR00819; HMM-score: 447.3)
• TheSEED: see SA2261
• PFAM:
  IT (CL0182) ABG_transport; AbgT putative transporter family (PF03806; HMM-score: 728.3)
  and 3 more
  Na_H_antiporter; Na+/H+ antiporter family (PF03553; HMM-score: 26.6)
  DcuC; C4-dicarboxylate anaerobic carrier (PF03606; HMM-score: 21.9)
  no clan defined DUF6338; Family of unknown function (DUF6338) (PF19865; HMM-score: 7.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 11
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9999
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0001
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.004399
  • TAT(Tat/SPI): 0.000242
  • LIPO(Sec/SPII): 0.001808
• predicted transmembrane helices (TMHMM): 12

⊟Accession numbers

• GI: 446124179 NCBI
• RefSeq: WP_000202034 NCBI
• UniProt: see SA2261

⊟Protein sequence

• MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTWVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIAASVVVLLPTILLVTTKLIIPRLGKYDDSLMHDDHEEASSHITDKEAHALKWANISFIVTIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: CodY see SA2261

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications