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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS08590 [old locus tag: SA1526 ]
  • pan locus tag?: SAUPAN004352000
  • symbol: SA_RS08590
  • pan gene symbol?: pde2
  • synonym: nrnA
  • product: bifunctional oligoribonuclease/PAP phosphatase NrnA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS08590 [old locus tag: SA1526 ]
  • symbol: SA_RS08590
  • product: bifunctional oligoribonuclease/PAP phosphatase NrnA
  • replicon: chromosome
  • strand: -
  • coordinates: 1744166..1745107
  • length: 942
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1744166..1745107) NCBI
  • BioCyc: SA_RS08590 BioCyc
  • MicrobesOnline: see SA1526

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGATTAGTACTTTGAATGAAATTATGAAATGTATCGAAGACAACGATACAATTATTATA
    CACAGACATGTTAGACCAGATCCAGATGCATATGGTTCACAACTTGGTTTAAAATACTAT
    ATTCAGCAGAAATTTCCGCAAAAGCAAGTATTTGCAGTGGGTGAAGCGGAATCATCATTA
    AGTTTTATTGGAGAGTTGGATAACATTGATGATAAAACATATCAAGATGCGCTTGTAATT
    GTATGTGATACTGCCAATGCTCCACGAATTGACGATGAACGATATAGTACAGGTAGTAAA
    CTTATTAAAATAGATCATCATCCTGCAGTTGATCAGTATGGTGATATTAATTTAGTTAAT
    ACGAACGCGTCATCTACAAGTGAAATCATTTATGATTTAATCTCACATTTTAATGATGAA
    GCAATTGTTAATAAAGATATCGCGAGTGTTTTATACCTTGGTATCGTCGGTGATACTGGG
    CGATTCCTTTTTAACAATACCTCAGAACATACTATGGAAATTGCTGGAAAGTTAATTGGG
    CATGATATTGATCATAATGCGCTATTAAATAAAATGATGGAGAAGGACCCAAAAATGTTG
    CCGTTTCAAGGTTATGTTTTACAACATTTCGAACTTATGGATGATGGATTCTGCCAAGTT
    AAAATAACTGAAGATGTATTGGAGCAATTCGGTATTCAGCCAAATGAAGCATCTCAGTTT
    GTTAATACAATTGCTGACATCAAAGGTTTGAAAATATGGGTGTTTGCAGTTGATGAGGGT
    AGTGAAATAAGATGTCGCTTACGCTCTAAAGGGCAATTGATTATTAATGATATTGCGCAA
    GATTTTGGTGGCGGTGGCCATCCGAATGCGTCAGGAGTTTCAGTGAACAGCTGGGATGAA
    TTTGAGCAACTTGCTACAGCTTTACGCACAAAACTTAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    942

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS08590 [old locus tag: SA1526 ]
  • symbol: SA_RS08590
  • description: bifunctional oligoribonuclease/PAP phosphatase NrnA
  • length: 313
  • theoretical pI: 4.46314
  • theoretical MW: 34999.2
  • GRAVY: -0.254633

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan glutamate racemase (TIGR00067; EC 5.1.1.3; HMM-score: 12.7)
  • TheSEED: see SA1526
  • PFAM:
    HAD (CL0137) DHH; DHH family (PF01368; HMM-score: 53.6)
    no clan defined DHHA1; DHHA1 domain (PF02272; HMM-score: 44)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003663
    • TAT(Tat/SPI): 0.00018
    • LIPO(Sec/SPII): 0.000907
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGSKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVNSWDEFEQLATALRTKLN

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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