PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_RS14385 [old locus tag: SAUSA300_2587 ]
• pan locus tag^?: SAUPAN006387000
• symbol: SAUSA300_RS14385
• pan gene symbol^?: asp1
• synonym:
• product: accessory Sec system protein Asp1

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_RS14385 [old locus tag: SAUSA300_2587 ]
• symbol: SAUSA300_RS14385
• product: accessory Sec system protein Asp1
• replicon: chromosome
• strand: -
• coordinates: 2808462..2810015
• length: 1554
• essential: unknown other strains

⊟Accession numbers

• Location: NC_007793 (2808462..2810015) NCBI
• BioCyc: SAUSA300_RS14385 BioCyc
• MicrobesOnline: see SAUSA300_2587

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  1501
  
  ATGAAATACTTTATTCCAGCTTGGTACGATGACCAACGATGGTGGCAAGACACGACTGTG
  CCGTATTATCAACTACAAAATAAGACGGAATTTGACGATATGATTAGTTTAATGGGAATG
  CACCTTGAAAATGACTTAGATTATCAACTGATTGTTCTCAATCATGCACCAAATTTAAGA
  ACATTTTTACATCGATATGACTTATATGAGACAAAGTATTCGTCTGTGTTTGATGAAATT
  CAAGGATTCAGTCACCATGCGCCACAAGCGATTAATTATCATCACTTAAAATGGCCGGAT
  GATGTTGAGTTTGTGTACACACCGTATTTATTAAAATGTGTGACGAGTGAACAGACCTAT
  ACAAATATTTATTTTAGTCAAGAAGGGTATTCAATTTGGTTTGAAGAATTTGAAAGAGAT
  CAGTTACAACGGCGTTATATTTTTGATGACAGAGGTTATTTATCAGCGATACGTTATTTT
  GATGATCAGGGAGAGGCTTCTTACCAAGAATATTTAACGATTAATGGAGATTGTGTACTT
  CATGAAGATTTGAAAAATGGCAGAGTCACTGTTTCAAAAAGATATCAACATCACTATCAA
  CAAACAGAATATAACAATATGGCTCAACTAATTGAAGAAAAATTTCAAGCAATGATTGCA
  CAACAAATACATGAAGATGATCATGTGATTGTGGCTTCAGATGCTAGGCACAATCGACAA
  ATAGCCAATCATATTCCAGCGAAATCATTAAGTTATTCATTTTTTAAAAATAGAAATGAA
  ACTGTGTCAGATGAGGAATATCAATCTATCGTAAAGAATGCCCATTTAATTGTTGATAGT
  GTGCAACTAGAACGTGATTTAATTAGTCATCAAGAGAAGTATCAGCGGGAGAATACAATG
  ATTCGAATCACACCATTTGAAACGAGACAATCACCTAATATAAGTAGTCAATTGATGGAA
  ACATTTATAGGTGTATGGATAGATGGTATGAGTGACGCTGATTTGCAACAAATGATGCAA
  CGACTTGTGGATTATATCGCACAGGAAGATTATTACCGTTTAATTTTATTATCGCGCCAT
  CAAAATGACATACCGATGTGGCTTCGTGAATGTATTACGTCGGTAAATGAGGAATACCAA
  GCTAAACAGAATGCGGATGTTAATGTTTCAGCATTAATGACACCTGAAGATCAAGATGAC
  ATCATTGCTGTTAAGACGATACATGCTGAACATGATGTTGTAGAAGCATTGCGGACGTTG
  CGACTTGTGATAGATATGTCAAAAGAACCTGACTTGTATTTACAAATTAGTGCAATTAGC
  GCTGGGATTCCACAAATTAATGGTCAACAAACAGATTACGTCTCTGATTATGACAATGGC
  CGTATTATAAATACAGTTGATGAATTAGATGATGCGTTAAATTATTATTTATTTTATTTG
  AAAAATTGGAATTATGCGTACGCCTATTCTTTAAAATTAATAGATGCATATGCTTCTAAG
  AATATTATTAATCAGCTCGATGAGTTAATAGAAGGTGAAAATGATGCCACGTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1380
  1440
  1500
  1554
  

⊟Protein

⊟General

• locus tag: SAUSA300_RS14385 [old locus tag: SAUSA300_2587 ]
• symbol: SAUSA300_RS14385
• description: accessory Sec system protein Asp1
• length: 517
• theoretical pI: 4.43636
• theoretical MW: 61258.8
• GRAVY: -0.585493

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Pathogenesis accessory Sec system protein Asp1 (TIGR03713; HMM-score: 733.4)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking accessory Sec system protein Asp1 (TIGR03713; HMM-score: 733.4)
• TheSEED: see SAUSA300_2587
• PFAM:
  GT-B (CL0113) Asp1; Accessory Sec system protein Asp1 (PF16993; HMM-score: 359.9)
  and 1 more
  Peptidase_CA (CL0125) Vasohibin; Vasohibin (PF14822; HMM-score: 13.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9387
  • Cytoplasmic Membrane Score: 0.0486
  • Cell wall & surface Score: 0.0006
  • Extracellular Score: 0.0121
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.003065
  • TAT(Tat/SPI): 0.000073
  • LIPO(Sec/SPII): 0.000422
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446795941 NCBI
• RefSeq: WP_000873197 NCBI
• UniProt: see SAUSA300_2587

⊟Protein sequence

• MKYFIPAWYDDQRWWQDTTVPYYQLQNKTEFDDMISLMGMHLENDLDYQLIVLNHAPNLRTFLHRYDLYETKYSSVFDEIQGFSHHAPQAINYHHLKWPDDVEFVYTPYLLKCVTSEQTYTNIYFSQEGYSIWFEEFERDQLQRRYIFDDRGYLSAIRYFDDQGEASYQEYLTINGDCVLHEDLKNGRVTVSKRYQHHYQQTEYNNMAQLIEEKFQAMIAQQIHEDDHVIVASDARHNRQIANHIPAKSLSYSFFKNRNETVSDEEYQSIVKNAHLIVDSVQLERDLISHQEKYQRENTMIRITPFETRQSPNISSQLMETFIGVWIDGMSDADLQQMMQRLVDYIAQEDYYRLILLSRHQNDIPMWLRECITSVNEEYQAKQNADVNVSALMTPEDQDDIIAVKTIHAEHDVVEALRTLRLVIDMSKEPDLYLQISAISAGIPQINGQQTDYVSDYDNGRIINTVDELDDALNYYLFYLKNWNYAYAYSLKLIDAYASKNIINQLDELIEGENDAT

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications