PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_RS07775 [old locus tag: SAUSA300_1425 ]
• pan locus tag^?: SAUPAN001437000
• symbol: SAUSA300_RS07775
• pan gene symbol^?: —
• synonym:
• product: DUF2800 domain-containing protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_RS07775 [old locus tag: SAUSA300_1425 ]
• symbol: SAUSA300_RS07775
• product: DUF2800 domain-containing protein
• replicon: chromosome
• strand: -
• coordinates: 1584001..1585167
• length: 1167
• essential: unknown other strains

⊟Accession numbers

• Location: NC_007793 (1584001..1585167) NCBI
• BioCyc: SAUSA300_RS07775 BioCyc
• MicrobesOnline: see SAUSA300_1425

⊟Phenotype

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⊟DNA sequence

• 1
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  ATGAAGCTAGATCACTCAAATAGAGCTCATGCAAAGCTTAGTGCAAGTGGAGCAAAACAA
  TGGCTAAACTGCCCACCGAGTATTAAGGCAAGTGAAGGTATTGCAGATAAAAGTACAGTT
  TTTGCCGAAGAAGGTACATTCGCCCATGAGTTAAGTGAGTTATATTTCAGCCTTAAATAT
  GAAGGCCTAACACAGTTTGAGTTTAATAAGGCTTTTCAAAATTATAAGAGAAATCAATAT
  TACAGCGAAGAATTGCGTGAATATGTGGAAGAGTATGTAGCTAATGTAGAAGAAAAATAT
  AACGAAGCTTTGAGTAGGGATAATGATGTAATAGCTTTATTTGAAACAAAATTAGATTTA
  GGTAAATACGTCCCTGAATCTTTTGGAACTGGTGATGTCATTATATTTTCAGGTGGTGTA
  CTTGAAATTATTGACCTTAAATATGGTAAAGGCATTGAAGTTTCAGCTATAGATAATCCT
  CAACTTAGATTATATGGCTTGGGCGCATATGAACTGCTTAGTTTAATGTATGACATTCAT
  ACAATTCGCATGACTATCATACAACCTCGAATAGATAACTTTTCTACTGAAGAGTTACCA
  ATATCAAGATTACTTCAATGGGGAGCCGATTTTGTTAAACCATTAGCCAGACTTGCTTAT
  AACGGTGGAGGAGAGTTTAAAGCAGGTAGTCATTGTAGATTCTGTAAGATAAATCATTCA
  TGTAGAACACGTGCAGAATACATGCAAAATGTGCCTCAAAAGCCACCACATTTGTTAAGT
  GATGAAGAGATTGCAGAACTTTTATATAAACTGCCTGATATCAAAAAATGGGCTGATGAA
  GTAGAACAATATGCACTAAATCAAGCGAAAGAAAATGATAAAAACTATCCTGGTTGGAAG
  CTTGTAGAAGGTCGTTCACGAAGAATGATAACTGATACAAAAGCAATGCTTGAAAAGTTA
  GTTGAAGCGGGTTATAAACCTGAAGATATTACAGAAACCAAGTTACTTAGCATTACGAAT
  TTAGAAAAATTAATTGGTAAAAAAGCATTTTCTAAAATTACAGAGGGTTTTATAGAAAAG
  CCGCAAGGTAAATTAACACTTGCTACCGAGTCGGATAAACGACCAGCTATAAAGCAATCT
  GCTGAAGATGATTTTGACAAACTATAA
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⊟Protein

⊟General

• locus tag: SAUSA300_RS07775 [old locus tag: SAUSA300_1425 ]
• symbol: SAUSA300_RS07775
• description: DUF2800 domain-containing protein
• length: 388
• theoretical pI: 5.40726
• theoretical MW: 44229.9
• GRAVY: -0.517526

⊟Function

• TIGRFAM:
• TheSEED: see SAUSA300_1425
• PFAM:
  PDDEXK (CL0236) DUF2800; Protein of unknown function (DUF2800) (PF10926; HMM-score: 441.2)
  and 1 more
  PDDEXK_1; PD-(D/E)XK nuclease superfamily (PF12705; HMM-score: 34.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.055436
  • TAT(Tat/SPI): 0.004146
  • LIPO(Sec/SPII): 0.011402
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446685206 NCBI
• RefSeq: WP_000762552 NCBI
• UniProt: see SAUSA300_1425

⊟Protein sequence

• MKLDHSNRAHAKLSASGAKQWLNCPPSIKASEGIADKSTVFAEEGTFAHELSELYFSLKYEGLTQFEFNKAFQNYKRNQYYSEELREYVEEYVANVEEKYNEALSRDNDVIALFETKLDLGKYVPESFGTGDVIIFSGGVLEIIDLKYGKGIEVSAIDNPQLRLYGLGAYELLSLMYDIHTIRMTIIQPRIDNFSTEELPISRLLQWGADFVKPLARLAYNGGGEFKAGSHCRFCKINHSCRTRAEYMQNVPQKPPHLLSDEEIAELLYKLPDIKKWADEVEQYALNQAKENDKNYPGWKLVEGRSRRMITDTKAMLEKLVEAGYKPEDITETKLLSITNLEKLIGKKAFSKITEGFIEKPQGKLTLATESDKRPAIKQSAEDDFDKL

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications